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Study on the piezoelectricity in bone in the MHz range

Research Project

Project/Area Number 24360161
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Measurement engineering
Research InstitutionDoshisha University

Principal Investigator

MATSUKAWA Mami  同志社大学, 理工学部, 教授 (60288602)

Co-Investigator(Kenkyū-buntansha) ATSUSHI Hosokawa  明石工業高等専門学校, 電気情報工学科, 准教授 (00321456)
長谷 芳樹  神戸市立工業高等専門学校, 電子工学科, 准教授 (60448769)
Co-Investigator(Renkei-kenkyūsha) YOSHIKI Nagatani  神戸市立工業高等専門学校, 電子工学科, 准教授 (60448769)
TAKAHIKO Yanagitani  早稲田大学先進理工学部, 電気・情報生命工学科, 准教授 (10450652)
HIRONOBU Hoshino  浜松医科大学, 医学部, 准教授 (70293636)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2012: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Keywords圧電 / 超音波 / 皮質骨 / 骨 / トランスデューサ / FDTD
Outline of Final Research Achievements

Ultrasonically induced electrical potentials in bone were studied experimentally. The potentials were observed by the irradiation of ultrasonic wave of 10 kPa and showed the existence of piezoelectricity in bone in the MHz range. This result indicates the possible contribution of piezoelectricity on the bone fracture curing process by the ultrasonic irradiation. The induced potentials were observed in the wet bone and did not depend on the alignment of HAp crystallites in bone. The polarity of induced potentials showed site dependence.
A piezoelectric FDTD simulation was performed to estimate the spatial distribution of electric fields during ultrasound propagation in bone. The results showed the dependence of the field on the bone fracture.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (36 results)

All 2015 2014 2013 2012

All Journal Article (14 results) (of which Peer Reviewed: 14 results,  Acknowledgement Compliant: 4 results) Presentation (22 results) (of which Invited: 1 results)

  • [Journal Article] Numerical simulation of piezoelectric effect of bone under ultrasound irradiation2015

    • Author(s)
      Atsushi Hosokawa
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: in press

    • NAID

      210000145437

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effects of microstructure and water on the electrical potentials in bone induced by ultrasound irradiation2015

    • Author(s)
      Hiroko Tsuneda, Sayaka Matsukawa, Shinji Takayanagi, Katsunori Mizuno, Takahiko Yanagigatani, Mami Matsukawa
    • Journal Title

      Applied Physics Letters

      Volume: 106 Issue: 7 Pages: 0737041-4

    • DOI

      10.1063/1.4909546

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Influence of the circumferential wave on the fast and slow wave propagation in small distal radius bone2014

    • Author(s)
      Isao Mano, kaoru Horii, Fuminori Fujita, Yoshiki Nagatani, Mami Matsukawa, Takahiko Otani
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 53 Issue: 7S Pages: 07KF07-07KF07

    • DOI

      10.7567/jjap.53.07kf07

    • NAID

      210000144258

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Fast and slow wave detection in bovine cancellous bone in vitro using bandlimited deconvolution and Prony's method2014

    • Author(s)
      Keith Wear, Yoshiki Nagatani, Katsunori Mizuno, Mami Matsukawa
    • Journal Title

      Journal of the Acoustical Society of America

      Volume: 136 Issue: 4 Pages: 2015-2024

    • DOI

      10.1121/1.4895668

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Local ultrasonic wave velocities in trabeculae measured by micro-Brillouin scattering2014

    • Author(s)
      R.Tsubota, K.Fukui, M.Matsukawa
    • Journal Title

      Journal of the acoustical society of America

      Volume: Vol.135 Issue: 2 Pages: EL109-EL114

    • DOI

      10.1121/1.4862883

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between ultrasonic backscatter and trabecular anisotropic microstructure in cancellous bone2014

    • Author(s)
      C. Liu, D. Ta, F. Fujita, T. Hachiken, M. Matsukawa, K. Mizuno, W. Wang
    • Journal Title

      Journal of Applied Physics

      Volume: Vol.115 Issue: 6

    • DOI

      10.1063/1.4865173

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Trial of human cross-sectional imaging In vivo, using ultrasonic echo waves2013

    • Author(s)
      I.Mano, M.Matsukawa, T.Otani
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 52 Issue: 7S Pages: 07HF05-07HF05

    • DOI

      10.7567/jjap.52.07hf05

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electrical potentials in bone induced by ultrasound irradiation in the megahertz range2013

    • Author(s)
      M. Okino, S. Coutelou, K. Mizuno, T. Yanagitani, M. Matsukawa
    • Journal Title

      Applied Physics Letters

      Volume: Vol. 103 Issue: 10 Pages: 103701-103701

    • DOI

      10.1063/1.4819853

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An experimental study on the ultrasonic wave propagation in cancellous bone: Waveform changes during propagation2013

    • Author(s)
      F. Fujita, K. Mizuno, M. Matsukawa
    • Journal Title

      Journal of the acoustical society of America

      Volume: Vol.134 Issue: 6 Pages: 4775-4781

    • DOI

      10.1121/1.4824970

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Measurement of wave velocity in cortical bone by micro-Brillouin scattering technique : effect of bone tissue properties2012

    • Author(s)
      Kenji Fukui, Shinji Takayanagi, Daisuke Suga, Mami Matsukawa
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 51 Issue: 7S Pages: 07GF20-07GF20

    • DOI

      10.1143/jjap.51.07gf20

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative investigation of elastic properties in a trabecula usingmicro-Brillouin scattering and scanning acoustic microscopy2012

    • Author(s)
      Kawabe, Fukui, Matsukawa, Granke, Saied, Grimal, Laugier
    • Journal Title

      Journal of Acoustical Society of America, Express letter

      Volume: 132 Issue: 1 Pages: EL54-EL60

    • DOI

      10.1121/1.4730329

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two-wave propagation imaging to evaluate the structure of cancellous bone2012

    • Author(s)
      Yamashita, Fujita, Mizuno, Mano, Matsukawa
    • Journal Title

      IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency control

      Volume: 59 Issue: 6 Pages: 1160-1166

    • DOI

      10.1109/tuffc.2012.2306

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Numerical simulation of change in trabecular structure due to boneremodeling under ultrasound propagation2012

    • Author(s)
      Hosokawa
    • Journal Title

      J. Mech. Med. Biol.

      Volume: 13 Issue: 01 Pages: 13500031-14

    • DOI

      10.1142/s0219519413500036

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of cortical bone layer on fast and slow waves in cancellous bone: Investigations using stratified models2012

    • Author(s)
      Hosokawa, Nagatani
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 51 Issue: 7S Pages: 07GF19-07GF19

    • DOI

      10.1143/jjap.51.07gf19

    • NAID

      210000140991

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 超音波照射によって生じる圧電効果の数値シミュレーション2015

    • Author(s)
      細川 篤
    • Organizer
      電子情報通信学会2015年総合大会
    • Place of Presentation
      草津市、立命館大学
    • Year and Date
      2015-03-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 骨トランスデューサから放射されるMHz域の超音波測定2015

    • Author(s)
      松川沙弥果, 常田裕子, 眞野功, 高柳真司, 松川真美
    • Organizer
      第62回応用物理学会春季学術講演会
    • Place of Presentation
      東海大学湘南キャンパス
    • Year and Date
      2015-03-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 超音波照射による骨中誘発電位の極性について2015

    • Author(s)
      常田裕子, 松川沙弥果, 真野功, 水野勝紀, 柳谷隆彦, 松川真美
    • Organizer
      圧電材料・デバイスシンポジウム2015
    • Place of Presentation
      東北大学
    • Year and Date
      2015-02-18 – 2015-02-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 骨の微細構造が超音波帯域の圧電性に与える影響2014

    • Author(s)
      常田裕子, 松川沙弥果, 眞野功, 水野勝紀, 柳谷隆彦, 高柳真司, 松川真美
    • Organizer
      第35回超音波エレクトロニクスの基礎と応用に関するシンポジウム
    • Place of Presentation
      明治大学御茶ノ水キャンパス
    • Year and Date
      2014-12-03 – 2014-12-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 超音波により励起される骨中電位の極性について2014

    • Author(s)
      常田裕子, 松川沙弥果, 眞野功, 水野勝紀, 柳谷隆彦, 高柳真司, 松川真美
    • Organizer
      電子情報通信学会超音波研究会
    • Place of Presentation
      山形大学
    • Year and Date
      2014-09-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] Induced electric potentials in bone by ultrasonic irradiation2014

    • Author(s)
      Mami Matsukawa
    • Organizer
      Ultrasonics 2014 -Ultrasonic-based applications: from analysis to synthesis-
    • Place of Presentation
      Caparica (Lisbon, Portugal)
    • Year and Date
      2014-09-15 – 2014-09-17
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Polarity of piezoelectric properties in bone induced by ultrasound irradiation2014

    • Author(s)
      Hiroko Tsuneda, Isao Mano, Elena Hernanz, Katsunori Mizuno, Takahiko Yanagitani, Shinji Takayanagi, Mami Matsukawa
    • Organizer
      2014 IEEE International Ultrasonics Symposium
    • Place of Presentation
      Chicago USA
    • Year and Date
      2014-09-03 – 2014-09-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] 海綿骨の超音波スペクトロスコピー2013

    • Author(s)
      松川真美
    • Organizer
      2013年第60回応用物理学会春季学術講演会(Invited)
    • Place of Presentation
      神奈川理工科大学
    • Year and Date
      2013-03-29
    • Related Report
      2012 Annual Research Report
  • [Presentation] Ultrasonic wave properties of human bone marrow in femur or tibia, European Symposium on Ultrasonic Characterization of Bone2013

    • Author(s)
      S. Kawasaki, K. Fujimori, T. Kawakami, T. Mihata, M. Matsukawa
    • Organizer
      European Symposium on Ultrasonic Characterization of Bone 2013
    • Place of Presentation
      University of Granada
    • Related Report
      2013 Annual Research Report
  • [Presentation] Electrical potentials in wet induced by ultrasound irradiatio2013

    • Author(s)
      H. Tsuneda, M. Okino, K. Mizuno, T. Yanagitani, S. Takayanagi, M. Matsukawa
    • Organizer
      European Symposium on Ultrasonic Characterization of Bone 2013
    • Place of Presentation
      University of Granada
    • Related Report
      2013 Annual Research Report
  • [Presentation] Clinical usefulness of the fast and slow wave system to discriminate fractures at the proximal femur2013

    • Author(s)
      I. Mano, M. Matsukawa, T. Otani, Y. Yoneda, K. Horii, K. Etoh, M. Sugimoto, H. Yokota, Y. Murakami, Y. Kotoura
    • Organizer
      European Symposium on Ultrasonic Characterization of Bone 2013
    • Place of Presentation
      University of Granada
    • Related Report
      2013 Annual Research Report
  • [Presentation] of fast wave in the initial state of wave propagation in cancellous bone2013

    • Author(s)
      F. Fujita, K. Mizuno, I. Mano, M. MatsukawaObservation
    • Organizer
      European Symposium on Ultrasonic Characterization of Bone 2013
    • Place of Presentation
      University of Granada
    • Related Report
      2013 Annual Research Report
  • [Presentation] Two wave phenomenon in a child radius model2013

    • Author(s)
      F. Fujita, K. Mizuno, I. Mano, M. Matsukawa
    • Organizer
      2013 Joint UFFC, EFTF and PFM symposium
    • Place of Presentation
      Prague Congress Centre
    • Related Report
      2013 Annual Research Report
  • [Presentation] Estimation of Wave Propagation inside Human Body while Walking and Running-Measurement of Vibration on Body Surface and 3-D Simulation2013

    • Author(s)
      Y. Nagatani, I. Mano, M. Matsukawa
    • Organizer
      2013 Joint UFFC, EFTF and PFM symposium
    • Place of Presentation
      Prague Congress Centre
    • Related Report
      2013 Annual Research Report
  • [Presentation] Assessment of bone quality by quantitative ultrasound measurement2013

    • Author(s)
      I. Mano, K. Horii, M. Matsukawa
    • Organizer
      The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      大阪国際会議場
    • Related Report
      2013 Annual Research Report
  • [Presentation] MHz域の超音波照射による骨の誘発電位2013

    • Author(s)
      常田裕子, 沖野正裕, 水野勝紀, 柳谷隆彦, 高柳真司, 松川真美
    • Organizer
      第33回日本骨形態計測学会
    • Place of Presentation
      アクトシティ浜松コングレスセンター
    • Related Report
      2013 Annual Research Report
  • [Presentation] 模擬ヒト橈骨中を伝搬する縦波超音波の実験的検討2013

    • Author(s)
      藤田文理, 八軒卓磨, 長谷芳樹, 眞野功, 水野勝紀, 松川真美
    • Organizer
      第34回超音波エレクトロニクスの基礎と応用に関するシンポジウム
    • Place of Presentation
      同志社大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] MHz域における骨の電気機械変換特性2012

    • Author(s)
      沖野、水野、柳谷、クテル、松川
    • Organizer
      第33回超音波エレクトロニクスの基礎と応用に関するシンポジウム
    • Place of Presentation
      千葉大学
    • Year and Date
      2012-11-15
    • Related Report
      2012 Annual Research Report
  • [Presentation] Numerical investigation of reflections of fast and slow longitudinal waves at a boundary between cancellous bone and cortical bone2012

    • Author(s)
      Hosokawa
    • Organizer
      2012 IEEE International Ultrasonics Symposium
    • Place of Presentation
      Dresden Conference Center(Germany)
    • Year and Date
      2012-10-10
    • Related Report
      2012 Annual Research Report
  • [Presentation] Behaviour of Ultrasonic Wave Propagation in Inferior Limb of Human Body -Experimental and Numerical Investigation using 3-D Elastic Human Model2012

    • Author(s)
      Nagatani
    • Organizer
      2012 IEEE International Ultrasonics Symposium
    • Place of Presentation
      Dresden Conference Center(Germany)
    • Year and Date
      2012-10-10
    • Related Report
      2012 Annual Research Report
  • [Presentation] Bone ultrasound transducer in the MHz range2012

    • Author(s)
      Okino, Mizuno, Takayanagi, Suga, Yanagitani, Matsukawa
    • Organizer
      2012 IEEE International Ultrasonics Symposium
    • Place of Presentation
      Dresden Conference Center(Germany)
    • Year and Date
      2012-10-09
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of boundary conditions on the two wave phenomenon in cancellous bone2012

    • Author(s)
      Matsukawa, Mizuno, Nagatani
    • Organizer
      Acoustics 2012 (Invited)
    • Place of Presentation
      HongKong conference center(Hong Kong)
    • Year and Date
      2012-05-17
    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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