|Budget Amount *help
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2014: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2012: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
|Outline of Final Research Achievements
We showed the possibility that Aβ43, an essential molecule for pathological process of Alzheimer’s disease, could induce channel activity. Also, we successfully prepared Aβ oligomers by PICUP (photo-induced cross-linking of unmodified proteins) method and established the purification procedure with HPLC.