A long-term follow-up study involving randomly-selected large-scale sample cohorts to extract evidence for health guidance

• Project/Area Number: 24390505
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Community health/Gerontological nurisng
• Research Institution: Nagoya University
• Principal Investigator: KAJITA ETSUKO 名古屋大学, 医学(系)研究科(研究院), 教授 (50135373)
• Co-Investigator(Kenkyū-buntansha): NAKATANI Yoshimi 福井県立大学, 看護福祉学部, 教授 (90217753) ; IKI Masayuki 近畿大学, 医学部, 教授 (50184388) ; TAMAKI Junko 大阪医科大学, 医学部, 教授 (90326356)
• Co-Investigator(Renkei-kenkyūsha): ITO Naoko 名古屋大学, 大学院医学系研究科, 助教 (80456681) ; OKAMURA Yukiko 中部大学, 生命健康学部, 講師 (40405220)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000); Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2012: ¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000)
• Keywords: 無作為集団 / 追跡研究 / 保健指導 / エビデンス

Outline of Final Research Achievements

A follow-up survey was conducted, involving randomly-selected subjects living in two municipalities of Japan who had first participated in the study in 1998 or fifteen years before the survey, to provide findings to promote research on longevity. The survey aimed to examine lifestyle and nutritional factors that help prevent females living in the community from developing cardiovascular disorders and fractures as the causes of conditions requiring nursing care, their QOL, and factors associated with lifestyle-related diseases. Nurses who serve as health advisors in the community collaborated with us to extract the evidence required to provide health advice in relation to lifestyle-related diseases, and develop guidelines for health advice based on the evidence.

Research Products

• [Journal Article] HDL subclasses heterogeneous in their associations with body fat, as measured by dual-energy X-ray absorptiometry (2015)
  • Author(s): Katsuyasu Kouda, Harunobu Nakamura, Yuki Fujita, Masami Hamada, Etsuko Kajita, Yoshimi Nakatani, Yuho Sato, Kazuhiro Uenishi, Masayuki Iki
  • Journal Title: Clinica Chmica Acta Volume: 444 Pages: 101-105
  • Peer Reviewed / Open Access
• [Journal Article] Cohort Profile : The Japanese Population-based Osteoporosis (JPOS) Cohort Study (2014)
  • Author(s): Iki M, Tamaki J, Sato Y, Morita A, Ikeda Y, Kajita E, Nishino H, Akiba T, Matsumoto T, Kagamimori S, Kagawa Y, Yoneshima H
  • Journal Title: Int. J. Epidemiol. Volume: 84 Pages: 1-10
  • DOI: 10.1093/ije/dyu084
  • Peer Reviewed / Open Access
• [Presentation] Association between concerns for falls and QOL in elderly Japanese women: A 9-year follow-up (2015)
  • Author(s): Etsuko Kajita, Masami Hamada, Syuichi Maeda, Sumie Mitamura, Masayuki Iki
  • Organizer: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
  • Place of Presentation: Milan(Itaria)
  • Year and Date: 2015-03-26 – 2015-03-29
• [Presentation] Incident clinical fracture was associated with increased risk of death after adjustment for frailty indices in elderly Japanese men: a cohort study (2015)
  • Author(s): Masayuki Iki, Yuki Fujita, Junko Tamaki, Katsuyasu Kouda, Akiko Yura, Yuho Sato, Jong-Seong Moon, Akihiro Harano, Kan Hazaki, Etsuko Kajita, Masami Hamada, Kiyomi Arai, Kimiko Tomioka, Nozomi Okamoto, Norio Kurumatani and Fujiwara-kyo Study Group
  • Organizer: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
  • Place of Presentation: Milan(Italia)
  • Year and Date: 2015-03-26 – 2015-03-29
• [Presentation] Incident osteoporotic fracture increases the risk of death independently of frailty indices in community-dwelling elderly Japanese men (2015)
  • Author(s): Masayuki Iki, Yuki Fujita, Junko Tamaki, Katsuyasu Kouda, Akiko Yura, Yuho Sato, Jong-Seong Moon, Akihiro Harano, Kan Hazaki, Masami Hamada, Kiyomi Arai, Etsuko Kajita, Kimiko Tomioka, Nozomi Okamoto, Norio Kurumatani and Fujiwara-kyo Study Group
  • Organizer: The 25th Annual Scientific Meeting of the Japan Epidemiological Asociation
  • Place of Presentation: Nagoya(Japan)
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] 海浜農業地区住民女性の骨折と健康関連QOL(Quality of Life)の関連 (2014)
  • Author(s): 濱田昌実、梶田悦子、伊木雅之
  • Organizer: 第73回日本公衆衛生学会
  • Place of Presentation: 宇都宮（栃木）
  • Year and Date: 2014-11-05 – 2014-11-07
• [Presentation] 地域在住女性において海綿骨微細構造指標Trabecular Bone Score (TBS)はFRAX®による骨折リスク評価能を改善する－JPOS Cohort Study－ (2014)
  • Author(s): 玉置淳子、伊木雅之、佐藤裕保、Renaud Winzenrieth、梶田悦子、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第16回日本骨粗鬆症学会
  • Place of Presentation: 東京
  • Year and Date: 2014-10-23 – 2014-10-25
• [Presentation] 中高年日本人女性において低骨格筋量は低骨密度に関連する (2014)
  • Author(s): 立木隆広、伊木雅之、北川淳、高平尚伸、玉置淳子、梶田悦子、佐藤裕保、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第16回日本骨粗鬆症学会
  • Place of Presentation: 東京
  • Year and Date: 2014-10-23 – 2014-10-25
• [Presentation] Skeletal muscle index using height overestimates muscle mass in elderly women: Japanese population-based osteoporosis (JPOS) cohort study (2014)
  • Author(s): Takahiro Tachiki, Masayuki Iki, Jun Kitagawa, Naonobu Takahira, Yuho Sato, Etsuko Kajita, Sadanobu Kagamimori, Yoshiko Kagawa, Hideo Yoneshima
  • Organizer: ASBMR 2014 Annual Meeting
  • Place of Presentation: Houston(USA)
  • Year and Date: 2014-09-12 – 2014-09-15
• [Presentation] Dose Trabecular Bone Score (TBS) Improbe the Predictive Ability of FRAX®? : The Japanese population-based osteoporosis (JPOS) cohort study (2014)
  • Author(s): J Tamaki, M Iki, Y Sato, R Winzenrieth, E Kajita, S Kagamimori, Y Kagawa, H Yoneshima, for JPOS Study Group
  • Organizer: ASBMR 2014 Annual Meeting
  • Place of Presentation: Houston(USA)
  • Year and Date: 2014-09-12 – 2014-09-15
• [Presentation] Age-related changes in bone mineral density, skeletal muscle mass, and muscle function in postmenopausal Japanese women (2014)
  • Author(s): Takahiro Tachiki, Jun Kitagawa, Naonobu Takahira, Masayuki Iki, Junko Tamaki, Yuho Sato, Etsuko Kajita, Sadanobu Kagamimori
  • Organizer: 第20回米国骨髄移植学会／国際骨髄移植研究会議合同会議
  • Place of Presentation: USA
• [Presentation] Japanese Population-based Osteoporosis (JPOS) Cohort Study15年次調査完遂 (2014)
  • Author(s): 伊木雅之、玉置淳子、梶田悦子、秋葉隆、松本俊夫、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第24回日本疫学会学術総会
  • Place of Presentation: 仙台市
• [Presentation] 無作為抽出標本の1５年間追跡データを用いたFRAX®の有用性の検討-JPOS Cohort Study (2014)
  • Author(s): 玉置淳子、伊木雅之、由良晶子、梶田悦子、佐藤裕保、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第24回日本疫学会学術総会
  • Place of Presentation: 仙台市
• [Presentation] 骨折リスク予測法FRAX(R)に基づく骨粗鬆症検診のシミュレーション (2013)
  • Author(s): 伊木雅之、玉置淳子、梶田悦子、鏡森定信、香川芳子、米島秀夫、JPOS Study Group
  • Organizer: 第72回日本公衆衛生学会総会
  • Place of Presentation: 津市
• [Presentation] 骨粗鬆症予防のための長期追跡調査による骨折の発生状況－JPOS Cohort Study－ (2013)
  • Author(s): 梶田悦子、伊木雅之、玉置淳子、門脇英子、佐藤裕保、中谷芳美、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第72回日本公衆衛生学会総会
  • Place of Presentation: 津市
• [Presentation] 10年間の追跡による椎体骨折とQOLの関連 - JPOS Cohort Study - (2012)
  • Author(s): 梶田悦子, 伊木雅之, 玉置淳子 ,門脇英子, 佐藤裕保, 鏡森定信, 香川芳子, 米島秀夫
  • Organizer: 第71回日本公衆衛生学会
  • Place of Presentation: サンルート国際ホテル山口(山口)
  • Year and Date: 2012-10-25
• [Presentation] 市町村の骨折・骨粗鬆症予防対策に対する認識と今後の課題 (2012)
  • Author(s): 中谷芳美, 梶田悦子, 玉置淳子, 伊木雅之
  • Organizer: 第71回日本公衆衛生学会
  • Place of Presentation: サンルート国際ホテル山口(山口)
  • Year and Date: 2012-10-25
• [Presentation] 閉経女性における体組成と骨密度の関連 - JPOS S tudy15年次調査による閉経後年数別検討 - (2012)
  • Author(s): 玉置淳子, 伊木雅之, 冬梅, 由良晶子, 甲田勝康, 藤田裕規, 佐藤裕保, 梶田悦子, 中谷芳美, 鏡森定信, 香川芳子, 米島秀夫
  • Organizer: 第71回日本公衆衛生学会
  • Place of Presentation: サンルート国際ホテル山口(山口)
  • Year and Date: 2012-10-25
• [Presentation] 閉経後女性における握力と大腿骨頸部骨密度は骨格筋量を介して関連している (2012)
  • Author(s): 立木隆弘, 北川淳, 高平尚伸, 伊木雅之, 玉置淳子, 梶田悦子, 佐藤裕保, 鏡森定信, 香川芳子, 米島秀夫
  • Organizer: 第14回日本骨粗鬆症学会
  • Place of Presentation: 新潟コンベンションセンター(新潟)
  • Year and Date: 2012-09-27