Scientific and Practical Approaches to Computationally Hard Problems
Project/Area Number |
24500023
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Fundamental theory of informatics
|
Research Institution | Tokyo Denki University |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
|
Keywords | 近似アルゴリズム / 固定パラメータアルゴリズム / バイオインフォマティクス / 組み合わせ最適化 / ハプロタイプアセンブリー / 網状ネットワーク / 生物系統樹のrSPR距離 / 中心列問題 / 生物系統樹のrSPR距離問題 / 最多内部頂点スパニング木問題 / scaffolding / グラフアルゴリズム / 完全マッチング / ハミルトンパス / 乱択アルゴリズム / アルゴリズムの設計と解析 / 最大一致森問題 / 網状ネットワーク問題 / ハプロタイプ組立問題 / Closest文字列問題 / 共有中心列問題 / 固有パラメータアルゴリズム / NP困難性 |
Outline of Final Research Achievements |
We mainly studied several important and fundamental combinatorial optimization problems in bioinformatics such as the rSPR distance problem of two phylogenetic trees, the reticulate network problem of multiple phylogenetic trees, and the closest string problem. All the studied problems are computationally hard and various algorithms had been designed for them before. In this project, we designed new algorithms for the problems and not only rigorously analyzed the theoretical performance of our new algorithms but also implemented them and compared their practical performance against the previous bests. Our results show that the new algorithms are the bests not only in theory but also in practice.
|
Report
(6 results)
Research Products
(22 results)
-
[Journal Article] Algorithms for Pedigree Comparison2017
Author(s)
Zhi-Zhong Chen, Q. Feng, C. Shen, J. Wang, and L. Wang
-
Journal Title
IEEE/ACM Transactions on Computational Biology and Bioinformatics
Volume: 印刷中
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-