• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Improvement of MRI compatible Au-Pt-8Nb alloys through controlling the microstructure

Research Project

Project/Area Number 24500528
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokushima

Principal Investigator

HAMADA Kenichi  徳島大学, ヘルスバイオサイエンス研究部, 教授 (00301317)

Research Collaborator HONDA Eiichi  
TAKEGAWA Emi  
INUI Shihoko  
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsアーチファクト / 磁化率 / MRI / Au合金 / 強度 / 加工性 / 金合金
Outline of Final Research Achievements

Workability of Au-5Pt-8Nb alloy ingot was insufficient and they showed serious cracks after cold-rolling. However, Au-5Pt-8Nb alloy wire was successfully produced using swaging process. Since the magnetic susceptibility of wire was slightly increased from Au-5Pt-8Nb ingot due to potential impurity elements absorbed during swaging process, the alloy composition was modified to Au-5Pt-7Nb. The ultimate strength/elongation of the wire could be changed from 540 MPa/25% to 630 MPa/13% using heat treatment. A prototype aneurysm clip could be produced from annealed soft wire. After aging treatment, the prototype clip showed the closing force required. Magnetic resonance image of the clip indicated that significant artifact was occurred around coil section of the clip. This artifact suggested that improvement of coil design was required to produce an artifact free clip.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (18 results)

All 2014 2013 2012 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (15 results) (of which Invited: 1 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Magnetic susceptibility and hardness of Au-xPt-yNb alloys for biomedical applications2013

    • Author(s)
      Emi Uyama, Shihoko Inui, Kenichi Hamada, Eiichi Honda, Kenzo Asaoka
    • Journal Title

      Acta Biomaterialia

      Volume: vol 9 Issue: 9 Pages: 8449-8453

    • DOI

      10.1016/j.actbio.2013.05.028

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] MRI artifact reduction of aneurysm clip made of non-magnetic Au-7Nb-5Pt alloy for biomedical applications2014

    • Author(s)
      Kenichi HAMADA, Emi UYAMA, Shihoko INUI and Eiichi HONDA
    • Organizer
      Materials Today Asia 2014
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2014-12-09 – 2014-12-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] MRIアーチファクトフリー生体医療用合金の開発 -Au-xPt-8Nb 合金の微細組織と機械的特性-2014

    • Author(s)
      乾志帆子,宇山恵美,浜田賢一,誉田栄一
    • Organizer
      第52回日本人工臓器学会大会
    • Place of Presentation
      京王プラザホテル札幌(北海道札幌市)
    • Year and Date
      2014-10-17 – 2014-10-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dynamic Hardness Evaluation of Two Phases of Au-xPt-8Nb Alloys for MRI-artifact-free Biomedical Devices2014

    • Author(s)
      Shihoko Inui, Emi Uyama, Eiichi Honda and Kenichi Hamada
    • Organizer
      26th European Conference on Biomaterials (ESB2014)
    • Place of Presentation
      Liverpool, UK
    • Year and Date
      2014-08-31 – 2014-09-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Au-xPt-8Nb合金の各相の硬さが合金全体の硬さに及ぼす影響2014

    • Author(s)
      宇山恵美,乾志帆子,浜田賢一
    • Organizer
      第63回日本歯科理工学会学術講演会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2014-04-12 – 2014-04-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 生体用非磁性Au-Pd基合金の特性2014

    • Author(s)
      浜田賢一、宇山恵美、乾 志帆子、誉田栄一
    • Organizer
      日本金属学会2014年春季(第154回)大会
    • Place of Presentation
      東京工業大学(東京都目黒区)
    • Related Report
      2013 Research-status Report
  • [Presentation] Magnetic-resonance-imaging Artifact-free Au-7Nb-5Pt Alloy: Mechanical Properties of Wire2013

    • Author(s)
      Kenichi HAMADA, Shihoko INUI, Emi UYAMA and Eiichi HONDA
    • Organizer
      International Conference on Processing & Manufacturing of Advanced Materials 2013 (Thermec’2013)
    • Place of Presentation
      Rio Hotel, Las Vegas, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Tensile Properties of Au-7Nb-5Pt and Au-8Nb-5Pt Alloy Wire for Use in MRI-Artifact-Free Biomedical Devices2013

    • Author(s)
      Kenichi HAMADA, Emi UYAMA, Shihoko INUI and Eiichi HONDA
    • Organizer
      25th European Conference on Biomaterials (ESB2013)
    • Place of Presentation
      Hotel Melia Castilla, Madrid, Spain
    • Related Report
      2013 Research-status Report
  • [Presentation] MRI-compatible Au-Pd-based Ternary Alloy for Biomedical Applications2013

    • Author(s)
      Emi UYAMA, Shihoko INUI, Kenichi HAMADA, Eiichi HONDA, Fumiaki KAWANO
    • Organizer
      25th European Conference on Biomaterials (ESB2013)
    • Place of Presentation
      Hotel Melia Castilla, Madrid, Spain
    • Related Report
      2013 Research-status Report
  • [Presentation] Microstructure of Magnetic-resonance-imaging Compatible Au-xPt-8Nb Alloy2013

    • Author(s)
      Emi UYAMA
    • Organizer
      91st General Session and Exhibition of the International Association for Dental Research
    • Place of Presentation
      Seattle Convention Center (USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] Magnetic-resonance-imaging Artifact-free Au‒8Nb‒5Pt Alloy: Mechanical Properties of Wire2013

    • Author(s)
      Kenichi HAMADA
    • Organizer
      91st General Session and Exhibition of the International Association for Dental Research
    • Place of Presentation
      Seattle Convention Center (USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] Properties of Au‒Pd Alloy for Magnetic-resonance-imaging Compatible Biomedical Devices2013

    • Author(s)
      Shihoko INUI
    • Organizer
      91st General Session and Exhibition of the International Association for Dental Research
    • Place of Presentation
      Seattle Convention Center (USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] MRI適合医療用金合金の開発2012

    • Author(s)
      浜田賢一
    • Organizer
      日本バイオマテリアル学会シンポジウム2012
    • Place of Presentation
      仙台国際センター(宮城県)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Au-Pt合金の磁化率への組成、加工および熱処理の影響2012

    • Author(s)
      宇山恵美
    • Organizer
      第60回日本歯科理工学会学術講演会
    • Place of Presentation
      九州大学(福岡県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 医療用非磁性Au-Pd基合金の開発:Au-Pd合金の磁化率と機械的特性2012

    • Author(s)
      乾志帆子
    • Organizer
      第60回日本歯科理工学会学術講演会
    • Place of Presentation
      九州大学(福岡県)
    • Related Report
      2012 Research-status Report
  • [Presentation] AuPt合金を用いた磁化率アーチファクト低減コイルの開発と評価2012

    • Author(s)
      中井隆介
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      京都国際会館(京都府)
    • Related Report
      2012 Research-status Report
  • [Book] バイオマテリアル研究の最前線2014

    • Author(s)
      浜田賢一
    • Total Pages
      250
    • Publisher
      日本金属学会
    • Related Report
      2014 Annual Research Report
  • [Remarks] 旬の研究紹介

    • URL

      http://www.tokushima-u.ac.jp/_files/00222488/kenkyubudayori_vol1.pdf

    • Related Report
      2014 Annual Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi