The role of Life Style Modification on Physical Activity in Patients with Irritable Bowel Syndrome

• Project/Area Number: 24500597
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Saitama Prefectural University
• Principal Investigator: HAMAGUCHI Toyohiro 埼玉県立大学, 保健医療福祉学部, 教授 (80296186)
• Co-Investigator(Kenkyū-buntansha): TAYAMA Jun 長崎大学, 大学院教育学研究科, 准教授 (10468324) ; SAIGO Tatsuo 長崎大学, 保健・医療推進センター, 研究員 (50622255) ; TOMIIE Tadaaki 北海道医療大学, 心理科学部, 教授 (50336286)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 過敏性腸症候群 / ストレス / 運動療法 / 歩行量 / 生活習慣 / リハビリテーション / 交感神経 / 副交感神経 / 作業療法

Outline of Final Research Achievements

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by chronic abdominal pain and abnormal bowel habituation. The symptoms of IBS are often aggravated by stress, which alters colonic motility and visceral perception. In addition, IBS is one of the serious causes of the early social maladjustment. In the treatment guidelines on digestive organ psychosomatic disorder (Fukudo, 2006), intervention to lifestyle modification including medication, teaching to eating habits and an exercise is shown as the first treatment stage. This study have highlighted the role of an exercise and lifestyle habits in IBS. This study reveals a possible association between exercise and lifestyle habits in IBS.

Research Products

• [Journal Article] Gastrointestinal specific anxiety in irritable bowel syndrome: validation of the Japanese version of the visceral sensitivity index for university students (2014)
  • Author(s): Saigo T, Tayama J, Hamaguchi T, Nakaya N, Tomiie T, Bernick PJ, Kanazawa M, Labus JS, Naliboff BD, Shirabe S, Fukudo S.
  • Journal Title: Biopsychosoc Med Volume: 8 Pages: 1-10
  • DOI: 10.1186/1751-0759-8-10
  • NAID: 120005438975
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Preceding stimulation affects brain activation in response to colonic distention in humans. (2013)
  • Author(s): Hamaguchi T, Kano M, Kanazawa M, Itoh M, Yanai K, Fukudo S.
  • Journal Title: Psychosomatic Medicine Volume: 75 Pages: 453-462
  • DOI: 10.1097/psy.0b013e3182926682
  • Peer Reviewed
• [Journal Article] Effects of preceding stimulation on brain activation in response to colonic distention in humans (2013)
  • Author(s): Toyohiro Hamaguchi, Michiko Kano, Motoyori Kanazawa, Masatoshi Itoh, Kazuhiko Yanai, Shin Fukudo
  • Journal Title: Psychosomatic Medicine Volume: 印刷中
  • Peer Reviewed
• [Journal Article] Effects of personality traits on the manifestations of irritable bowel syndrome. (2012)
  • Author(s): Tayama J, Nakaya N, Hamaguchi T, Tomiie T, Shinozaki M, Saigo T, Shirabe S, Fukudo S.
  • Journal Title: Biopsychosoc Med Volume: 6(1) Pages: 1-18
  • DOI: 10.1186/1751-0759-6-20
  • Peer Reviewed
• [Journal Article] Effect of baseline self-efficacy on physical activity and psychological stress after a one-week pedometer intervention (2012)
  • Author(s): Jun Tayama, Hironori Yamasaki, Mami Tamai, Masaki Hayashida, Susumu Shirabe, Kazuki Nishiura, Toyohiro Hamaguchi, Tadaaki Tomiie, Naoki Nakaya
  • Journal Title: Perceptual and Motor Skills Volume: 114:2 Pages: 407-418
  • NAID: 120004664321
  • Peer Reviewed
• [Journal Article] アルツハイマー病と生活習慣・リスク要因-運動と認知症 (2012)
  • Author(s): 濱口豊太，石岡俊之
  • Journal Title: 脳21 Volume: 15:2 Pages: 45-50
• [Presentation] Preceding stimulation affects brain activation in response to visceral stimulation (2014)
  • Author(s): Hamaguchi T, Kano M, Kanazawa M, Itoh M, Yanai K and Fukudo S
  • Organizer: 13th International Congress of Behavioral Medicine
  • Place of Presentation: Groningen, The Netherlands
  • Year and Date: 2014-08-20 – 2014-08-23
• [Presentation] Neuroticism and Irritable Bowel Syndrome (2014)
  • Author(s): Jun Tayama, Naoki Nakaya, Toyohiro Hamaguchi, Tadaaki Tomiie,Masae Shinozaki, Tatsuo Saigo, Susumu Shirabe, and Shin Fukudo
  • Organizer: 13th International Congress of Behavioral Medicine
  • Place of Presentation: Groningen, The Netherlands
  • Year and Date: 2014-08-20 – 2014-08-23
• [Presentation] Effectiveness of group cognitive behavioral therapy for the prevention of depression: pilot study (2014)
  • Author(s): Jun Tayama, Tatsuo Saigo, Sayaka Ogawa, Peter Bernick, Nozomi Fukuhara, Toyohiro Hamaguchi, Tadaaki Tomiie, Naoki Nakaya, Shin Fukudo, Masaki Hayashida, Susumu Shirabe
  • Organizer: 13th International Congress of Behavioral Medicine
  • Place of Presentation: Groningen, The Netherlands
  • Year and Date: 2014-08-20 – 2014-08-23
• [Presentation] Changes in Heart Rate Variability after Physical Exercise in Patients with Irritable Bowel Syndrome (2014)
  • Author(s): Hamaguchi T, Tayama J, Saigou T, Tomiie T, Kanazawa M and Fukudo S
  • Organizer: 13th International Congress of Behavioral Medicine
  • Place of Presentation: Groningen, The Netherlands
  • Year and Date: 2014-08-20 – 2014-08-23
• [Presentation] A Controled Trial of Behavioral Therapy in Rehavilitation for Immobility in Patients with Post-Stroke Depression (2014)
  • Author(s): Takizawa H, Ishioka T, Sasao K, Nakamura H, Kayaba K, Tomiie T, Tayama J, Saigo T, and Hamaguchi T
  • Organizer: 13th International Congress of Behavioral Medicine
  • Place of Presentation: Groningen, The Netherlands
  • Year and Date: 2014-08-20 – 2014-08-23
• [Presentation] Changes in salivary physiological stress markers induced by aromatherapy and physical therapy in patients with IBS (2013)
  • Author(s): Hamaguchi T, Tayama T, Saigou T, Tomiie T, Kanazawa M, Fukudo S.
  • Organizer: World Congress on Psychosomatic Medicine
  • Place of Presentation: Lisbobn, Portgul
• [Presentation] The development of the Japanese version of the sleep hygiene index (2013)
  • Author(s): Sugakawa J, Mastin D F, Tayama T, Hamaguchi T, Tomiie T.
  • Organizer: World Congress on Psychosomatic Medicine
  • Place of Presentation: Lisbobn, Portgul
• [Presentation] Does the psycho-education of PTSD using comics promote the motivation for the clinical treatment? (2013)
  • Author(s): Tomiie T, Ohno F, Sakakibara K, Hamaguchi T, Tayama J, Fukudo S.
  • Organizer: World Congress on Psychosomatic Medicine
  • Place of Presentation: Lisbobn, Portgul
• [Presentation] Menstrual cycle phase-related change in depressive mood, attentional and cognitive function in women with PMDD (2013)
  • Author(s): Ohkubo M, Shinkawa H, Tayama T, Hamaguchi T, Tomiie T.
  • Organizer: World Congress on Psychosomatic Medicine
  • Place of Presentation: Lisbobn, Portgul
• [Presentation] Antidepressant reduces gut stimulation-induced brain activation in men (2013)
  • Author(s): Fukudo S, Itoh N, Kanazawa M, Watanabe S, Hamaguchi T, Morishita J, Kano M, Tashiro M.
  • Organizer: World Congress on Psychosomatic Medicine
  • Place of Presentation: Lisbobn, Portgul
• [Presentation] The relationship between type a behavior pattern and obesity in Japanese workers (2013)
  • Author(s): Ogawa S, Ymasaki H, Saigo T, Hattori T, Tomiie T, Hamaguchi T, Sirabe S, Munakata M, Tayama J.
  • Organizer: World Congress on Psychosomatic Medicine
  • Place of Presentation: Lisbobn, Portgul
• [Presentation] 大学生のIBS有症状者に対する運動介入効果の検証 (2013)
  • Author(s): 濱口豊太，田山淳，富家直明，西郷達雄，中谷直樹，金澤素，福土審
  • Organizer: 第19回日本行動医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 大学生のメンタルヘルスとIBS (2013)
  • Author(s): 田山淳，中谷直樹，濱口豊太，富家直明，篠崎雅江，西郷達雄，調漸，福土審
  • Organizer: 第19回日本行動医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 反証と適応的思考の思考カテゴリー分類の試み (2013)
  • Author(s): 西塚拓海，新川広樹，富家直明，田山淳，濱口豊太
  • Organizer: 第19回日本行動医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 過敏性腸症候群と機能性ディスペプシアにおけるBody Vigilanceの差の検討 (2013)
  • Author(s): 西郷達雄，田山淳，富家直明，中谷直樹，濱口豊太，坂野雄二，福土審
  • Organizer: 第19回日本行動医学会学術集会
  • Place of Presentation: 東京
• [Presentation] 高齢者の身体活動に影響を及ぼす生活習慣病と心理社会的要因 (2013)
  • Author(s): 中島愛，村椿智彦，土岐瑞貴，村上亮，濱口豊太，富家直明，中野倫仁，坂野雄二
  • Organizer: 第19回日本行動医学会学術集会
  • Place of Presentation: 東京
• [Presentation] Accelerometer and autonomic nerves response to physical exercise in patients with irritable bowel syndrome (2012)
  • Author(s): Toyihiro Hamaguchi, Kunihiko Shimizu, Jun Tayama, Tadaaki Tomiie, Tatsuo Saigou, Motoyori Kanazawa, Koji Sakurai, Shin Fukudo
  • Organizer: 12th International Congress of Behavioral Medicine
  • Place of Presentation: Budapest, Hungry
• [Presentation] The Effect of Personality on Irritable Bowel Syndrome (2012)
  • Author(s): Tayama J, Nakaya N, Hamaguchi T, Tomiie T, Shinozaki M, Saigo T, Hayashida M, Fukudo S.
  • Organizer: 12th International Congress of Behavioral Medicine
  • Place of Presentation: Budapest, Hungry
• [Presentation] Corticotropin-Releasing Hormone is Associated with Exaggerated Brain Activity and Pituitary-Adrenal Response during Colorectal Distention in IBS (2012)
  • Author(s): Yukari Tanaka, Joe Morishita, Motoyori Kanazawa, Toyohiro Hamaguchi, Manabu Tashiro, Shin Fukudo
  • Organizer: Digestive Disease Week 2012
  • Place of Presentation: San Diego, USA
• [Presentation] セロトニントランスポーター遺伝子多型が直腸刺激時の局所脳反応性に与える影響 (2012)
  • Author(s): 田代学, 福土審, 金澤素, 水野資子, 濱口豊太, 鹿野理子, 遠藤由香, 本郷道夫, 糸山泰人, 谷内一彦, 青木正志
  • Organizer: 第52回日本核医学会学術総会
  • Place of Presentation: 札幌