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Effects of a Renal Rehabilitation Exercise Program in Patients with CKD

Research Project

Project/Area Number 24500638
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionTsukuba University of Technology (2013-2014)
Tohoku University (2012)

Principal Investigator

MIURA Misa  筑波技術大学, 保健科学部, 准教授 (30612014)

Co-Investigator(Kenkyū-buntansha) ITO Osamu  東北大学, 医学(系)研究科(研究院), 准教授 (00361072)
KOHZUKI Masahiro  東北大学, 医学(系)研究科(研究院), 教授 (70234698)
NAGASAKA Makoto  東北大学, 医学(系)研究科(研究院), 臨床准教授 (70375062)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords腎機能障害 / 血液透析 / 有酸素運動 / 微弱下肢電気刺激 / 身体機能改善 / エルゴメータ運動 / 運動耐容能 / 筋力 / 腎臓リハビリテーション / 透析中の運動 / 透析中の微弱電気刺激 / 筋力改善 / 透析効率改善 / 糖尿病性腎症 / 慢性糸球体腎炎 / 慢性腎不全 / 心臓交感神経活動 / 人工透析 / 電気刺激 / 心臓自律神経機能 / 安全性の確認 / 副交感神経機能改善
Outline of Final Research Achievements

Hemodialysis patients show reduced physical function and greater risk of arteriosclerosis because of hypertension, metabolic disturbances, and vascular calcification. Meanwhile, exercise training in hemodialysis patients improves fitness, physical function, quality of life. This study aimed to determine whether aerobic training and electrical stimulation to skeletal muscles for 12 weeks could improve physical function and dialysis efficacy in patients with end-stage renal disease (ESRD).A total of 30 ESRD patients (18 males, 12 females; age: 72.9±7.7 years) were randomized to receive 12 weeks of aerobic training exercise , electrical stimulation to the lower limbs , or no specific intervention. In this study, the safety and efficacy of training and electrical stimulation were confirmed without sudden drop of blood pressure or any other side effects. Therefore, training might improve physical function with specific whole-body effects as well as local effects in ESRD patients.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (33 results)

All 2015 2014 2013 2012

All Journal Article (13 results) (of which Peer Reviewed: 8 results,  Open Access: 1 results) Presentation (16 results) (of which Invited: 6 results) Book (4 results)

  • [Journal Article] Effects of electrical stimulation of the abdomen in inactive elderly patients with chronic indwelling urinary catheters.2014

    • Author(s)
      Miura M, Tanaka N, Nagasaka M, Iguchi M, Ito O, Kohzuki M.
    • Journal Title

      NTUT Education of Disabilities

      Volume: 12 Pages: 11-13

    • NAID

      120005397327

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Classification of the physical disabilities and actual conditions of visceral impairment in Japan.2014

    • Author(s)
      Kohzuki M.
    • Journal Title

      Asian Journal of Human Services

      Volume: 6 Pages: 125-137

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高血圧自然発症ラットの血圧と腎 Nitric oxide 合成酵素に対する Pitavastatin 長期投与の効果.2014

    • Author(s)
      伊藤 修,胡 丐尊,戎 栄,徐 斌,作山晃裕,坂田佳子,伊藤大亮,上 月正博.
    • Journal Title

      Therapeutic Research

      Volume: 35 Pages: 987-988

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 血行再建術の適応外と判断された PAD 患者の歩行能力と 健康関連 QOL に対する運動療法の効果.2014

    • Author(s)
      金 珉智,伊藤 修,三浦美佐,柿花隆昭,森 信芳,長坂 誠,海老原覚, 赤松大二朗, 上月正博.
    • Journal Title

      Asian Journal of Human Services

      Volume: 6 Pages: 47-58

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Short term and long term effects of lower body positive pressure (LBPP) exercise for late elderly patients.2013

    • Author(s)
      Miura M, Nagasaka M, Ito O, Kawai Y, Kohzuki M.
    • Journal Title

      Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine.

      Volume: 1 Pages: 139-140

    • Related Report
      2013 Research-status Report
  • [Journal Article] Effects of electrical stimulation to skeletal muscle and exercise on the autonomic nervous activity.2013

    • Author(s)
      Miura M, Ito O, Nagasaka M, Kohzuki M.
    • Journal Title

      Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine.

      Volume: 1 Pages: 192-192

    • Related Report
      2013 Research-status Report
  • [Journal Article] Effect of music therapy and combination therapy on the autonomic nervous activity.2013

    • Author(s)
      Jia T, Miura M, Ito O, Nagasaka M, Rong R, Kohzuki M.
    • Journal Title

      Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine.

      Volume: 1 Pages: 209-209

    • Related Report
      2013 Research-status Report
  • [Journal Article] Acute and Chronic Effects of Lower Body Positive Pressure Exercise on the Very Elderly: A Pilot Study.2013

    • Author(s)
      Misa Miura, Masahiro Kohzuki, Osamu Ito, Makoto Nagasaka, Hiroaki Kinoshita,Yasuaki Kawai.
    • Journal Title

      Int J Phys Med Rehabil

      Volume: 1 Issue: 09 Pages: 9-13

    • DOI

      10.4172/2329-9096.1000173

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Renal rehabilitation in patients with chronic kidney disease.2013

    • Author(s)
      Kohzuki M, Sakata Y, Mori N, Ebihara S, Ito O
    • Journal Title

      Proceedings of the 7th World Congress of the International Society

      Volume: 1 Pages: 5-6

    • Related Report
      2013 Research-status Report
  • [Journal Article] 透析患者における生活習慣対策 運動不足2012

    • Author(s)
      三浦美佐、伊藤修
    • Journal Title

      臨床透析

      Volume: 28 Pages: 45-50

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 透析中の運動療法2012

    • Author(s)
      三浦美佐、上月正博
    • Journal Title

      透析フロンテイア

      Volume: 22 Pages: 20-22

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 透析中の運動療法と問題点2012

    • Author(s)
      上月正博
    • Journal Title

      理学療法

      Volume: 29 Pages: 1092-1099

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 新たな内部障害リハビリテーション2012

    • Author(s)
      伊藤修
    • Journal Title

      東北医学会雑誌

      Volume: 124 Pages: 30-32

    • Related Report
      2012 Research-status Report
  • [Presentation] Effects of a Renal Rehabilitation Exercise Program in Patients with CKD: Controlled Trial2015

    • Author(s)
      Miura M, Oowada S, Hirayama A, Ito O, Kohzuki M.
    • Organizer
      52nd ERA-EDTA Congress
    • Place of Presentation
      London(England)
    • Year and Date
      2015-05-28 – 2015-05-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] 腎機能障 害者の心臓自律神経活動と運動耐容能の比較.2014

    • Author(s)
      三浦美佐, 上月正博, 松下昌之助, 平山 暁, 坂田佳子, 伊藤 修.
    • Organizer
      第 1 回呼吸・心血管・糖尿病理学療 法学会合同学術集会
    • Place of Presentation
      JA共済ビル(東京都、千代田区)
    • Year and Date
      2014-12-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] Effects of aerobic training on exercise tolerance and the autonomic nervous activity in patients with chronic kidney disease.2014

    • Author(s)
      Miura M, Kohzuki M, Sakata Y, Ito O, Hirayama A, Matsushita S.
    • Organizer
      Asian Preventive Cardiology & Cardiac Rehabilitation Conference
    • Place of Presentation
      Hong Kong (China)
    • Year and Date
      2014-11-06 – 2014-11-09
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Effect of comprehensive rehabilitation in non-alcoholic fatty liver disease (NAFLD).2014

    • Author(s)
      Ito O, Sakata Y, Mori N, Kohzuki M.
    • Organizer
      8th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Cancun (Mexico)
    • Year and Date
      2014-06-01 – 2014-06-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Effects of music and exercise combination on cardiac autonomix nervous system.2014

    • Author(s)
      Jia T, Sakata Y, Miura M, Kohzuki M.
    • Organizer
      8th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Cancun (Mexico)
    • Year and Date
      2014-06-01 – 2014-06-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Benefical effects of exercise training in cardio-renal syndrome.2014

    • Author(s)
      Ito O.
    • Organizer
      International Symposium for 50th Aniversary of Japanese Association of Rehabilitation Medicine
    • Place of Presentation
      東京フォーラム(東京都、千代田区)
    • Year and Date
      2014-04-19
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 血液透析患者と非血液透析者での運動耐容能と心臓自律神経活動の比較2014

    • Author(s)
      三浦美佐,櫻庭陽,松下昌之助,平山暁,石塚和重,伊藤修,上月正博.
    • Organizer
      第4回日本腎臓リハビリテーション学会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 血液透析中の患者に対する灸治療の試み~電子温灸器を用いた一症例~.2014

    • Author(s)
      櫻庭陽, 三浦美佐,近藤宏,森山朝正,平山暁,石津隆
    • Organizer
      第4回日本腎臓リハビリテーション学会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Related Report
      2013 Research-status Report
  • [Presentation] Renal Rehabilitation in Japan.2013

    • Author(s)
      Kohzuki M, Ito O.
    • Organizer
      7th World Congress of the International
    • Place of Presentation
      National Convention Center (Beijing,China)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Effects of exercise therapy on walking ability and health-related quality of life in patients with severe peripheral arterial disease.2013

    • Author(s)
      Ito O, Kim MJ, Miura M, Kakihana T, Mori N, Nagasaka M, Ebihara S, Kohzuki M.
    • Organizer
      7th World Congress of the International
    • Place of Presentation
      National Convention Center (Beijing,China)
    • Related Report
      2013 Research-status Report
  • [Presentation] Electrical stimulation of skeletal muscles in patients with heart failure: analternative to aerobic training?2013

    • Author(s)
      Kohzuki M.
    • Organizer
      7th World Congress of the International
    • Place of Presentation
      National Convention Center (Beijing,China)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Effect of music therapy and combination therapy on the autonomic nervous activity.2013

    • Author(s)
      Jia T, Miura M, Ito O, Rong R, Kohzuki M
    • Organizer
      7th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      China,Beijing
    • Related Report
      2012 Research-status Report
  • [Presentation] Short-term and long-term effects by the exercise using lower body positive pressure-bearing walking machine for late-stage elderly patients2013

    • Author(s)
      Miura M, Nagasaka M, Ito O, Kawai Y, Kohzuki M
    • Organizer
      7th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      China,Beijing
    • Related Report
      2012 Research-status Report
  • [Presentation] Surface Electrical stimulation to the abdomen improves motor performances in the inactive elderly.2013

    • Author(s)
      Miura M, Kohzuki M, Ito O, Nagasaka M, Seki K, Handa
    • Organizer
      7th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      China,Beijing
    • Related Report
      2012 Research-status Report
  • [Presentation] 中等症以上のPAD 患者における歩行能力と健康関連QOL に対する運動療法の効果2012

    • Author(s)
      伊藤修、上月正博
    • Organizer
      第18 回日本心臓リハビリテーション学会
    • Place of Presentation
      さいたま
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 腹筋運動と腹部表面電気刺激が自律神経活動に与える影響2012

    • Author(s)
      三浦美佐、長坂誠、伊藤修、上月正博
    • Organizer
      第32回日本リハビリテーション医学会東北地方会
    • Place of Presentation
      山形
    • Related Report
      2012 Research-status Report
    • Invited
  • [Book] 呼吸リハビリテーションの実際.包括的呼吸リハビリテーションポケットマニュアル(上月正博、海老原覚編)2013

    • Author(s)
      三浦美佐
    • Total Pages
      252
    • Publisher
      診断と治療社
    • Related Report
      2013 Research-status Report
  • [Book] 付録 病態サマリ,リハ記録など書類の書き方.包括的呼吸リハビリテーションポケットマニュアル(上月正博、海老原覚編)2013

    • Author(s)
      三浦美佐
    • Total Pages
      252
    • Publisher
      診断と治療社
    • Related Report
      2013 Research-status Report
  • [Book] 腎疾患.今日のリハビリテーション指針(伊藤利之,江藤文夫,木村章男編集)2013

    • Author(s)
      上月正博
    • Total Pages
      599
    • Publisher
      医学書院
    • Related Report
      2013 Research-status Report
  • [Book] 高齢社心血管疾患における運動療法の意義.心臓リハビリテーション(上月正博編集)2013

    • Author(s)
      上月正博
    • Total Pages
      506
    • Publisher
      医歯薬出版
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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