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long term changes of vascular endothelial function in young healthy subjects

Research Project

Project/Area Number 24500855
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionOsaka Kyoiku University

Principal Investigator

MATSUMOTO Tetsuya  大阪教育大学, 教育学部, 教授 (70273406)

Co-Investigator(Kenkyū-buntansha) NAKAE Ichiro  滋賀医科大学, 医学部, 助教 (20314148)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords血管内皮機能 / 生活習慣 / 若年者 / 血管機能 / 若年
Outline of Final Research Achievements

Endothelial dysfunction is a key step in the initiation and progression of atherosclerosis. Few data with effects of lifestyle on endothelial function are available in healthy university students. Thus, we evaluated prospectively the association of lifestyle with endothelial function in university students. Endothelial function was assessed by digital reactive hyperemia peripheral arterial tonometry (RH-PAT), utilizing Endo-PAT 1500 (Itamar Medical, Caesarea). All subjects (18.5±0.5 years) underwent questionnaires and reactive hyperemia index (RHI) measurements at the start of university life and after a 1-year and 2-year follow-up. No significant correlation between RHI values and physical activity, sleeping hours, skipping breakfast, current cigarette use, alcohol consumption, or body mass index was observed. In conclusion, poor lifestyle behaviors may be related to endothelial dysfunction in future postgraduate days.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (6 results)

All 2015 2014 Other

All Journal Article (2 results) Presentation (4 results)

  • [Journal Article] 若年健常者の血管内皮機能と生活習慣の関係2015

    • Author(s)
      松本鉄也
    • Journal Title

      大阪教育大学紀要

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 心拍変動に対する精油の効果2014

    • Author(s)
      下村奈々子、黒田圭子、松本鉄也
    • Journal Title

      大阪教育大学紀要

      Volume: 62 Pages: 57-64

    • NAID

      120005400144

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
  • [Presentation] Relationship between ventilatory efficacy and visceral adiposity: mechanistic insights into obesity paradox2014

    • Author(s)
      Hayashi H, Kawaguchi T, Matsumoto T, Fujita M, Horie M
    • Organizer
      第20回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-07-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 運動耐容能における血管内皮機能の役割2014

    • Author(s)
      林秀樹、岩井宏治、飛田良、木下妙子、川口民郎、松本鉄也、藤田正俊、堀江稔
    • Organizer
      第20回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-07-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 心臓リハビリテーションと関連他領域との接点を改めて探る

    • Author(s)
      松本鉄也
    • Organizer
      第18回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      埼玉
    • Related Report
      2012 Research-status Report
  • [Presentation] Passive whole-body exercise training with periodic acceleration improves endothelial function in sedentary subjects

    • Author(s)
      Tetsuya Matsumoto
    • Organizer
      European society of cardiology congress 2012
    • Place of Presentation
      munich
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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