Study of effects of maternal nutritional status during pregnancy and lactation period on nutrient absorption and metabolism function.
Project/Area Number |
24500990
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Eating habits, studies on eating habits
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Research Institution | University of Nagasaki |
Principal Investigator |
SURUGA KAZUHITO 長崎県立大学, 看護栄養学部, 准教授 (70315852)
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Co-Investigator(Kenkyū-buntansha) |
YAMAGUCHI Noriaki 長崎県立大学, 看護栄養学部, 助教 (80516295)
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Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 妊娠期 / 授乳期 / 脂質代謝 / ビタミンA吸収・代謝 / 小腸 / 糖質代謝 / ビタミンA代謝 / DoHad / 妊娠・授乳期 / 糖質・脂質吸収・代謝 / エピジェネティクス |
Outline of Final Research Achievements |
The offspring from dams fed a moderate caloric restricted diet in lactation period showed lower postprandial serum triglycerides levels and hepatic triglyceride levels. The offspring from dams fed a high-fat diet or caloric restricted diet in pregnancy and lactation period accelerated small intestinal vitamin A absorptive function and its hepatic storage function. These results suggested that nutritional status in pregnancy and/or lactation period influenced not only lipid but also vitamin A absorption and metabolism.
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Report
(4 results)
Research Products
(11 results)
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[Journal Article] High-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats.2015
Author(s)
Ichimura M, Kawase M, Masuzumi M, Sakaki M, Nagata Y, Tanaka K, Suruga K, Tamaru S, Kato S, Tsuneyama K, Omagari K.
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Journal Title
Hepatolgy Research.
Volume: 45
Pages: 458~469
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Abdominal subcutaneous adipose tissue accumulation is positively correlated with hepatic steatosis in Sprague-Dawley rats.2014
Author(s)
Omagari K, Yoshikawa C, Inoue S, Tanaka Y, Murayama T, Ichimura M, Miyata A, Mori S, Kamogawa M, Hirano E, Kato S, Suruga K, Tsuneyama K.
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Journal Title
Acta Medica Nagasakiensia
Volume: 59
Pages: 47~56
Related Report
Peer Reviewed / Acknowledgement Compliant
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