The development of chrononutrition-based dietary instructions for the prevention and treatment of lifestyle-related diseases
| Project/Area Number |
24501028
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Department of Clinical Research, National Hospital Organization Kyoto Medical Center |
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Principal Investigator |
TSUZAKI Kokoro 独立行政法人国立病院機構(京都医療センター臨床研究センター), 臨床研究企画運営部, 研究員 (80450881)
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| Co-Investigator(Kenkyū-buntansha) |
SAKANE Naoki 独立行政法人国立病院機構(京都医療センター臨床研究センター), 臨床研究企画運営部, 研究室長(予防医学) (40335443)
KOTANI Kazuhiko 自治医科大学, 医学部, 准教授 (60335510)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 時間栄養学 / 脂質代謝 / 生活習慣病 / 食事指導 / 予防医学 |
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| Outline of Final Research Achievements |
We investigated the relationships among eating schedule, lipoprotein metabolisms (small dense LDL; sdLDL), and the CLOCK 3111T/C polymorphism in women with dyslipidemia. In carriers of T/T homozygotes, the area of sdLDL was slightly higher than that in carriers of the C alleles (T/C or C/C). As carriers of T/T homozygotes had breakfast earlier, their morning fasting time was shorter than carriers of the C alleles.
Interventions were performed simultaneously in rotating shift and day shift groups to assess whether the group-based lifestyle intervention affects body weight in male shift workers. There was no difference in body weight between the 2 groups before the intervention; however, weight loss was significantly smaller in the rotating shift group than that in day shift groups after the intervention.
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Report
(4 results)
Research Products
(20 results)
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[Journal Article] Circadian Rhythm Genes CLOCK and PER3 Polymorphisms and Morning Gastric Motility in Humans.2015
Author(s)
Yamaguchi M, Kotani K, Tsuzaki K, Takagi A, Motokubota N, Komai N, Sakane, N, Moritani T, Nagai, N.
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Journal Title
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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