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Electrophoretic Designer Polyesters and Application for Bone-Regeneration Scaffold

Research Project

Project/Area Number 24550132
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Polymer chemistry
Research InstitutionNagoya Institute of Technology

Principal Investigator

TAKASU AKINORI  名古屋工業大学, 工学(系)研究科(研究院), 教授 (30303697)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords電気泳動堆積(EPD) / ポリ(エステル-スルホン) / 非イオン性高分子 / 生体活性ガラス / 光触媒 / コーティング / ポリ(2-オキサゾリン) / 電気泳動 / ポリエステル / 電気泳動堆積 / チオール・エン反応 / バイオミネラリエーション / 複合材料 / 酸化チタン
Outline of Final Research Achievements

A room temperature thiol-ene click polymerization afforded a poly(ester-sulfide), which represents the first in a new class of click polyesters. Subsequent Oxone oxidation of the poly(ester-sulfide) led to the corresponding poly(ester-sulfone), which had improved thermal stability in comparison with the parent poly(ester-sulfide). A bioactive glass/poly(ester-sulfone) composite could be deposited on a stainless-steel anode by electrophoretic deposition (EPD). Hydroxyapatite was found on the surface of electrophoretically deposited bioactive glass/poly(ester-sulfone) composites that had been immersed in simulated body fluid (SBF) for 2 weeks. This bioactive glass/poly(ester-sulfone) composite might therefore find use as a surface coating for implantable medical devices on which a hydroxyapatite layer can form post implantation to strengthen the interface between the implant and host bone.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (25 results)

All 2015 2014 2013 2012 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 3 results) Presentation (19 results) (of which Invited: 1 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Design of Electrophoretic and Biocompatible Poly(2-oxazoline)s Initiated by Perfluoroalkanesulfoneimides and Electrophoretic Deposition with Bioactive Glass2015

    • Author(s)
      T. Hayashi and A. Takasu
    • Journal Title

      Biomacromolecules

      Volume: 16 Issue: 4 Pages: 1259-1266

    • DOI

      10.1021/acs.biomac.5b00043

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Anode-Selective Coating of Titanium (IV) Oxide (TiO2) Using Electrophoretic Sulfone-Containing Click Polyester2014

    • Author(s)
      T. Fukuoka and A. Takasu
    • Journal Title

      Macromolecules

      Volume: 4 Issue: 31 Pages: 15983-15994

    • DOI

      10.1039/c4ra01170h

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Synthesis of Electrophoretic Poly(ester-sulfone) Gel via Thiol-Yne Click Gelation2014

    • Author(s)
      Y. Mano, Y. Nagao, Y., and A. Takasu
    • Journal Title

      Polymer Journal

      Volume: 46 Issue: 10 Pages: 682-687

    • DOI

      10.1038/pj.2014.54

    • NAID

      40020221800

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Anodeselective Eletrophoretic Deposition of a Bioactive Glass/SulfoneContaining Click Polyester Composite2012

    • Author(s)
      Nagao, Y.; Takasu, A.; Boccaccin, A.
    • Journal Title

      Macromolecules

      Volume: (in press) Issue: 8 Pages: 3326-3334

    • DOI

      10.1021/ma300396p

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 電気泳動する非イオン性高分子の設計とスマートコーティング2014

    • Author(s)
      高須 昭則
    • Organizer
      第29回中国四国地区高分子若手研究会
    • Place of Presentation
      サンポートホール高松
    • Year and Date
      2014-10-30 – 2014-10-31
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Design of Electrophoretic Poly(2-oxazoline)s For Hybridization with Bioactive Glass2014

    • Author(s)
      林 輝成, 高須 昭則
    • Organizer
      5th International Conference on Electrophoretic Deposition: Fundamentals and Applications
    • Place of Presentation
      Hernstein, Austria
    • Year and Date
      2014-10-05 – 2014-10-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] Electrophoretic Vinyl Polymers Prepared Via Atom Transfer Radical Polymerization and Smart Coating on Metals2014

    • Author(s)
      亀山 友美, 高須 昭則
    • Organizer
      5th International Conference on Electrophoretic Deposition: Fundamentals and Applications
    • Place of Presentation
      Hernstein, Austria
    • Year and Date
      2014-10-05 – 2014-10-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 新規開始剤による2-オキサゾリン類のカチオン開環重合と 生体活性ガラスとの複合化2014

    • Author(s)
      林 輝成, 高須 昭則
    • Organizer
      第63回高分子討論会
    • Place of Presentation
      長崎大学
    • Year and Date
      2014-09-24 – 2014-09-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Design of electrophoretic poly(2-oxazoline)s using sulfoneimides as the initiator and hybridization with bioactive glass2014

    • Author(s)
      林 輝成, 高須 昭則
    • Organizer
      第248回アメリカ化学会国際会議
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2014-08-10 – 2014-08-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] Electrophoretic vinyl polymers via atom transfer radical polymerization of a methacrylate containing sulfide2014

    • Author(s)
      亀山 友美, 高須 昭則
    • Organizer
      第248回アメリカ化学会国際会議
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2014-08-10 – 2014-08-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] スルホンイミドを開始剤に用いたポリ(2-オキサゾリン)類の設計と電気泳動挙動2014

    • Author(s)
      林 輝成, 高須 昭則
    • Organizer
      第63回高分子年次大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-05-28 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 電気泳動するポリ(エステル-スルホン)の構造因子の決定と溶媒効果2014

    • Author(s)
      木村 恭敏, 高須 昭則
    • Organizer
      第63回高分子年次大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-05-28 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] スルホニル基を有するポリメタクリル酸エステルの電気泳動挙動2014

    • Author(s)
      亀山 友美, 高須 昭則
    • Organizer
      第63回高分子年次大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-05-28 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 電気泳動するビニルポリマーの設計と合成2014

    • Author(s)
      亀山 友美, 高須 昭則
    • Organizer
      第63回高分子年次大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-05-28 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] Design of Electrophoretic Poly(ester-sulfone)s and Smart Coating of Titanium Oxide2013

    • Author(s)
      Takuya Fukuoka, Akinori Takasu
    • Organizer
      Pacific Polymer Conference
    • Place of Presentation
      Kaohsiung Taiwan
    • Related Report
      2013 Research-status Report
  • [Presentation] 電気泳動するポリエステルを用いた光触媒のスマートコーティング2013

    • Author(s)
      福岡 拓也, 高須 昭則
    • Organizer
      第44回中部化学関係学協会支部連合秋季大会
    • Place of Presentation
      静岡大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 電気泳動するポリエステルと機能性無機物質との複合化2013

    • Author(s)
      福岡 拓也, 高須 昭則
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 電気泳動するポリエステルと無機ブロックの複合化2013

    • Author(s)
      福岡 拓也, 高須 昭則
    • Organizer
      第62回高分子学会年次大会
    • Place of Presentation
      国立 京都国際会館
    • Related Report
      2013 Research-status Report
  • [Presentation] 電気泳動するポリ(エステル-スルホン)を用いた生物活性ガラスのスマートコーティング2012

    • Author(s)
      福岡拓也、高須昭則
    • Organizer
      第141回東海高分子研究会
    • Place of Presentation
      榊原温泉
    • Related Report
      2012 Research-status Report
  • [Presentation] Sulfone-Containing Click Polyester for Anode-Selective Smart Coating of Bioactive Glass2012

    • Author(s)
      長尾 優、高須昭則
    • Organizer
      IUMRS-International Conference on Electronic Materials
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report
  • [Presentation] ポリ(エステル―スルホン)を用いた生物活性ガラスの電極選択的電気泳動コーティング2012

    • Author(s)
      福岡拓也, 長尾優, 高須昭則
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋工業大学
    • Related Report
      2012 Research-status Report
  • [Presentation] Design of Electrophoretic Poly(ester-sulfone) and Smart Coating of Bioactive Glass by Electrophoretic Deposition (EPD)2012

    • Author(s)
      Takuya Fukuoka, Yu Nagao, Akinori Takasu
    • Organizer
      The Socity of Polymer Science, Japan
    • Place of Presentation
      神戸
    • Related Report
      2012 Research-status Report
  • [Presentation] 電気泳動するポリエステルの設計とバイオガラスのスマートコーティング2012

    • Author(s)
      長尾 優、高須昭則
    • Organizer
      第43回中部関連学協会支部連合秋季大会
    • Place of Presentation
      名古屋工業大学
    • Related Report
      2012 Research-status Report
  • [Book] “Cationic Ring-Opening Polymerization” In Encyclopedia of Polymeric Nanomaterials2015

    • Author(s)
      A. Takasu, T. Hayashi
    • Total Pages
      8
    • Publisher
      Springer
    • Related Report
      2014 Annual Research Report
  • [Remarks] 研究室ホームページ

    • URL

      http://polychem.web.nitech.ac.jp/public_html/index.html

    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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