Investigation of organic compounds which detoxified ciguatera fish poisoning, isolated from some medical plants and marine organisms
| Project/Area Number |
24550192
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemistry related to living body
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | シガテラ解毒活性 / 化学構造 / 植物 / 海洋生物 / 構造活性相関 / マレーシア / 国際情報交換 / 海綿 / キダチトウガラシ / ザクロ / ベニスモモ / ペプチド / アルカロイド / 紅藻 / ブロモインドール |
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| Outline of Final Research Achievements |
Ciguatera fish poisoning (CFP) is usually a nonfatal illness such as fever and diarrhea, caused by ingestion of various fishes living in the tropics and subtropics. Here, we studied some organic compounds which detoxified CFP, isolated from some medical plants and marine organisms in Southern area. We also carried out the structure-activity relationship study of the related compounds about bromopyrroles, bromoindoles, and capsaicins.
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Report
(4 results)
Research Products
(14 results)
