Analysis of ubiquitin receptors on regulatory functions of protein degradation
| Project/Area Number |
24570160
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Functional biochemistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SEKIGUCHI Takeshi 九州大学, 医学(系)研究科(研究院), 助教 (60187846)
山本 泰 岡山大学, 自然科学研究科, 教授 (40091251)
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| Co-Investigator(Renkei-kenkyūsha) |
YAMAMOTO Yasushi (40091251)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 細胞内タンパク質分解 / ユビキチン / 塩ストレス / Gタンパク質 / 栄養ストレス / 葉緑体 / 光ストレス / タンパク質分解 / TORC1複合体 / チラコイド膜 / プロテアーゼ / UBL-UBAタンパク質 / Dsk2 / Irc22 / ユビキチンレセプター / 高塩ストレス / Gtr1-Gtr2 |
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| Outline of Final Research Achievements |
Ubiquitin-dependent protein degradation plays important roles in stress responses of extra- and intra-cellular environment. In this study, we analyzed the regulation of protein degradation in stress responses using budding yeast and chloroplast. The results indicate that UBL-UBA protein Dsk2 is involved in salt stress, Gtr1-Gtr2 complex is involved in nutrient stress, and FtsH-thylakoid structure is involved in D1 degradation in chloroplast.
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Report
(4 results)
Research Products
(18 results)
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[Journal Article] Quality control of Photosystem II: Direct imaging of the changes in the thylakoid structure and ldistribution of FRtsH proteases in spinachchloroplasts under light stress.2014
Author(s)
Yoshioka-Nishimura M, Nanba,D, Takaki, T, Ohba C, Tsumura N, Morita N, Sakamoto H, Murata K, Yamamoto Y.
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Journal Title
Plant Cell Physiol.
Volume: 55
Issue: 7
Pages: 1255-1265
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] A New Subspecies Identification and Population Study of the Asian Small-clawed Otter (Aonyx cinereus) in the Malay Peninsula and Southern Thailand Based on Fecal DNA Method.2014
Author(s)
Rosli M.K.A., Syed-Shabthar S.M.F., Abdul-Patah P., Abdul-Samad Z., Abdul S.N, Burhanuddin M.N., Zulkifli N.A., Shukor M.N., Budsabong K., Changtragoon S., Sekiguchi T, Sasaki H, Md-Zain B.M.
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Journal Title
The Scientific World Journal
Volume: 2014
Pages: 1-11
DOI
Related Report
Peer Reviewed
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