Biosynthesis of structurally unique microbial secondary metabolites
| Project/Area Number |
24580166
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | Toyama Prefectural University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 微生物 / 二次代謝 / 生合成 / ポリケチド / 放線菌 / 糸状菌 / タイ |
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| Outline of Final Research Achievements |
Elucidation of biosynthetic mechanisms of structurally unique natural products makes it possible to understand the general principle of generation of structure diversity in natural products and utilize biosynthetic enzymes to create new natural products. Furthermore, it can provide useful information for the construction of potential compound library for drug discovery. In this study, we analyzed the biosynthetic origins and biosynthetic genes of several new secondary metabolites discovered in our laboratory from microorganisms and elucidated novel biosynthetic reactions involved in their synthesis.
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Report
(5 results)
Research Products
(11 results)
