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Understanding of malformation and mal-pigmentation of Heterosomata, and development of prevention method for staining-type hyper-melanosis

Research Project

Project/Area Number 24580266
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General fisheries
Research InstitutionKyoto University

Principal Investigator

TAGAWA Masatomo  京都大学, (連合)農学研究科(研究院), 准教授 (20226947)

Research Collaborator MATSUDA Taihei  道立総合研究機構, 栽培水産試験場, 主査
MIYAMA Yoshifumi  千葉水総研, 種苗生産研, 主任上席研究員
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords形態異常 / カレイ類 / 二次黒化 / ホルモン / ストレス / 成長速度 / 有眼側化因子 / 着色型黒化 / コルチゾル / 種苗生産 / 有眼側化 / マツカワ / ヒラメ / 黒色素胞 / 櫛鱗 / メラニン凝集ホルモン
Outline of Final Research Achievements

In heterosomata, the frequent occurrence of malformation and mal-pigmentation of juveniles is one of the most serious obstacles for efficient seed-production. This study was aimed to clarify the fundamental nature of the malformation and staining-type hyper-melanosis of the blind side.
By detailed analysis of malformation occurrence in red halibut, it is suggested that growth speed and stress independently affect the asymmetrical formation of the body and hyper-melanosis, respectively. The responsiveness of larval-type melanophores of barfin flounder against melanin-concentrating hormone suggested the larval nature of the blind side. In Japanese flounder, we preliminary found that stress stimulates, and uneven bottom prevents, the enlargement of staining type hyper-melanosis, respectively. In addition, presence of inducing substance(s) for ocular-side characteristics was suggested by transplantation experiment of scales.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (16 results)

All 2015 2014 2013 2012

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Acknowledgement Compliant: 2 results) Presentation (10 results)

  • [Journal Article] Effects of time and duration of rearing with bottom sand on the occurrence and expansion of staining-type hypermelanosis in the Japanese flounder Paralichthys olivaceus.2014

    • Author(s)
      Toshinori Isojima, Naoshi Makino, Yoshifumi Miyama, Masatomo Tagawa
    • Journal Title

      Fisheries Science

      Volume: 80 Issue: 4 Pages: 785-794

    • DOI

      10.1007/s12562-014-0755-5

    • NAID

      120005540405

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Transplantation of pigmented and non-pigmented scales into the ocular and blind sides of the Japanese flounder Paralichthys olivaceus, suggesting the presence of ocular-side characteristic inducer in pigmented scales.2014

    • Author(s)
      Toshinori Isojima, Masatomo Tagawa
    • Journal Title

      Fisheries Science

      Volume: 80 Issue: 5 Pages: 1027-1035

    • DOI

      10.1007/s12562-014-0784-0

    • NAID

      120005540406

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Progression of staining-type hypermelanosis on the blind side in normally metamorphosed juveniles and pigmentation progression in pseudoalbino juveniles of the Japanese flounder Paralichthys olivaceus using individual identification.2013

    • Author(s)
      Toshinori Isojima, Naoshi Makino, Masato Takakusagi, Masatomo Tagawa
    • Journal Title

      Fisheries Science

      Volume: 79 Issue: 5 Pages: 787-797

    • DOI

      10.1007/s12562-013-0655-0

    • NAID

      10031191431

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Developmental changes in melanophores and their asymmetrical responsiveness to melanin-concentrating hormone during metamorphosis in barfin flounder (Verasper moseri)2013

    • Author(s)
      Yoshikawa, N., Matsuda, T., Takahashi, A., Tagawa, M.
    • Journal Title

      General and Comparative Endocrinology

      Volume: 194 Pages: 118-123

    • DOI

      10.1016/j.ygcen.2013.09.006

    • NAID

      120005341898

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Formation process of staining-type hypermelanosis in Japanese flounder juveniles revealed by examination of chromatophores and scales.2013

    • Author(s)
      Toshinori Isojima, Hirohito Tsuji, Reiji Masuda, Masatomo Tagawa
    • Journal Title

      Fisheries Science

      Volume: 79 Issue: 2 Pages: 231-242

    • DOI

      10.1007/s12562-013-0600-2

    • NAID

      10031138660

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Gonadal development of the primitive flatfish Psettodes erumei in Kota Kinabalu, Sabah, Malaysia.2012

    • Author(s)
      Naoki Yoshikawa, Thamootharan Mammaran, Elvin Michael Bavoh, Masaru Tanaka, Masatomo Tagawa
    • Journal Title

      Aquaculture Science

      Volume: 60 Pages: 475-483

    • NAID

      130005062479

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 砂敷によるヒラメ着色型黒化防除の機構―コルチゾルによる促進と凹凸面による抑制―2015

    • Author(s)
      山本一毅・深山義文・益田玲爾・田川正朋
    • Organizer
      平成27年度日本水産学会春季大会
    • Place of Presentation
      東京海洋大学品川キャンパス
    • Year and Date
      2015-03-27 – 2015-03-31
    • Related Report
      2014 Research-status Report
  • [Presentation] 飼育下アカガレイの多様な形態異常防除に向けた試みー出現機構の成長とストレスに基づく理解ー2015

    • Author(s)
      浅田憲貴・松田泰平・田川正朋
    • Organizer
      平成27年度日本水産学会春季大会
    • Place of Presentation
      東京海洋大学品川キャンパス
    • Year and Date
      2015-03-27 – 2015-03-31
    • Related Report
      2014 Research-status Report
  • [Presentation] 飼育下アカガレイの多様な形態異常防除に向けた試みー飼育密度の検討ー2014

    • Author(s)
      浅田憲貴・松田泰平・田川正朋
    • Organizer
      平成26年度日本水産学会春季大会
    • Place of Presentation
      北海道大学(函館)
    • Related Report
      2013 Research-status Report
  • [Presentation] 飼育下アカガレイの多様な形態異常防除に向けた試みー成長履歴の検討ー2014

    • Author(s)
      浅田憲貴・松田泰平・田川正朋
    • Organizer
      平成26年度日本水産学会春季大会
    • Place of Presentation
      北海道大学(函館)
    • Related Report
      2013 Research-status Report
  • [Presentation] 飼育下アカガレイの多様な形態異常防除に向けた試みー飼育水温の検討ー2013

    • Author(s)
      浅田憲貴・松田泰平・田川正朋
    • Organizer
      平成25年度日本水産学会秋季大会
    • Place of Presentation
      三重大学
    • Related Report
      2013 Research-status Report
  • [Presentation] ヒラメ無眼側黒化の程度におよぼす黒化開始時期および黒化中断の影響2013

    • Author(s)
      礒島俊実・深山義文・牧野直・田川正朋
    • Organizer
      平成25年度日本水産学会春期大会
    • Place of Presentation
      東京都 東京海洋大学
    • Related Report
      2012 Research-status Report
  • [Presentation] 飼育下のアカガレイに見られる多様な形態異常は眼と体色の組み合わせの異常によって生じる2013

    • Author(s)
      浅田憲貴・松田泰平・田川正朋
    • Organizer
      平成25年度日本水産学会春期大会
    • Place of Presentation
      東京都 東京海洋大学
    • Related Report
      2012 Research-status Report
  • [Presentation] ヒラメ無眼側における着色型黒化進行過程の個体識別による検討2012

    • Author(s)
      礒島俊実・高草木将人・牧野直・田川正朋
    • Organizer
      平成24年度日本水産学会秋期大会
    • Place of Presentation
      下関市 水産大学校
    • Related Report
      2012 Research-status Report
  • [Presentation] 底砂の有無がヒラメの無眼側傷修復部の黒化に与える影響2012

    • Author(s)
      越後はるな・藤浪祐一郎・田川正朋
    • Organizer
      平成24年度日本水産学会秋期大会
    • Place of Presentation
      下関市 水産大学校
    • Related Report
      2012 Research-status Report
  • [Presentation] マツカワにおけるメラニン凝集ホルモン(MCH)反応性は変態後期に左右差を生じる2012

    • Author(s)
      吉川尚樹・松田泰平・高橋明義・田川正朋
    • Organizer
      第37回 日本比較内分泌学会大会
    • Place of Presentation
      福井市 福井大学
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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