| Project/Area Number |
24591602
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | The University of Tokushima |
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Principal Investigator |
SAKATA Hiromi 徳島大学, ヘルスバイオサイエンス研究部, 講師 (50294666)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUI Yoshihiro 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 (50144168)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 概日リズム / 脳発達 / 深部体温 / 明暗周期 / 母仔分離 / ラット / 摂食 / 時計遺伝子 / 視交叉上核 |
|---|
| Outline of Final Research Achievements |
Rat pups under went the maternal separation during for
12 hours a day from postnatal days 13 with a synchronized timing of separation/cohabitation with light ON or OFF, or with 3-hour delayed timing from light ON or OFF. As a result, the emergence of a transient and acute decrease in deep body temperature, which is characteristic in prewearning pups, was entrained a light and dark cycle, but not timing of maternal separation/cohabitation. A maternal separation under constant lightness revealed that if there was no in light condition as a time cue, the transient and acute decrease in the deep body temperature entrained maternal separation/cohabitation.
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