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A novel technique for the assessment of tissue microcirculation and investigation of precise angiosome in patients with critical limb ischemia

Research Project

Project/Area Number 24591869
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General surgery
Research InstitutionTokyo Medical and Dental University

Principal Investigator

KUDO TOSHIFUMI  東京医科歯科大学, 医学部附属病院, 講師 (50431911)

Co-Investigator(Kenkyū-buntansha) INOUE Yoshinori  東京医科歯科大学, 医歯(薬)学総合研究科, 講師 (70280964)
JIBIKI Masatoshi  国際医療福祉大学, 大学病院, 准教授 (50422481)
TOYOHUKU Takahiro  東京医科歯科大学, 医学部附属病院, 助教 (20625066)
YOKOO Satoshi  群馬大学, 医学(系)研究科(研究院), 教授 (00322206)
MIYAZAKI Hidetaka  群馬大学, 医学部附属病院, 講師 (70420271)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords重症虚血肢 / アンジオサム / 微小循環 / 蛍光色素 / 末梢動脈疾患 / アンギオサム / インドシアニングリーン / 蛍光色素血管造影 / 下肢虚血
Outline of Final Research Achievements

It is very important to assess local circulation in the lower extremity in a patient with peripheral arterial disease (PAD).
In the current study, a novel technique to assess tissue microcirculation in a foot in a patient with PAD was developed and more precise angiosome was investigated.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (8 results)

All 2014 2013

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 3 results) Presentation (2 results)

  • [Journal Article] Quantitative evaluation of microvascular dysfunction in peripheral neuropathy with diabetes by indocyanine green angiography2014

    • Author(s)
      Igari K, Kudo T, Uchiyama H, Toyofuku T, Inoue Y
    • Journal Title

      Diabetes Res Clin Pract

      Volume: 104 Issue: 1 Pages: 121-5

    • DOI

      10.1016/j.diabres.2014.01.022

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Intraarterial injection of indocyanine green for evaluation of peripheral blood circulation in patients with peripheral arterial disease2014

    • Author(s)
      Igari K, Kudo T, Uchiyama H, Toyofuku T, Inoue Y
    • Journal Title

      Ann Vasc Surg

      Volume: 28 Issue: 5 Pages: 1280-5

    • DOI

      10.1016/j.avsg.2013.12.036

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Indocyanine green angiography for the diagnosis of peripheral arterial disease with isolated infrapopliteal lesions2014

    • Author(s)
      Igari K, Kudo T, Uchiyama H, Toyofuku T, Inoue Y
    • Journal Title

      Ann Vasc Surg

      Volume: 28 Issue: 6 Pages: 1479-84

    • DOI

      10.1016/j.avsg.2014.03.024

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A quantitative method for evaluating local perfusion using indocyanine green fluorescence imaging2013

    • Author(s)
      Terasaki H, Inoue Y, Sugano N, Jibiki M, Kudo T, Lepäntalo M, Venermo M
    • Journal Title

      Annals of Vascular Surgery

      Volume: 27 Issue: 8 Pages: 1154-1161

    • DOI

      10.1016/j.avsg.2013.02.011

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quantitative evaluation of the outcomes of revascularization procedures for peripheral arterial disease using indocyanine green angiography2013

    • Author(s)
      Igari K, Kudo T, Toyofuku T, Jibiki M, Inoue Y, Kawano T
    • Journal Title

      Eur J Vasc Endovasc Surg

      Volume: 46 Issue: 4 Pages: 460-465

    • DOI

      10.1016/j.ejvs.2013.07.016

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A quantitative method for evaluating local perfusion using indocyanine green fluorescence imaging2013

    • Author(s)
      Hiroaki Terasaki, Yoshinori Inoue, Norihide Sugano, Masatoshi Jibiki, Toshihumi Kudo, Mauri Lepäntalo, Maarit Venermo
    • Journal Title

      Annals of Vascular Surgery

      Volume: in press

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 末梢動脈疾患に対する血行再建術におけるICG 蛍光造影法を用いた定量的評価法の確立2014

    • Author(s)
      猪狩 公宏,工藤 敏文,中村 政宏,葛井総太郎 西澤 真人,内山 英俊,小泉 伸也,豊福 崇浩、井上 芳徳
    • Organizer
      第 42 回 日本血管外科学会学術総会
    • Place of Presentation
      青森県青森市
    • Year and Date
      2014-05-21 – 2014-05-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] 末梢循環評価におけるICG蛍光造影法を用いた定量的評価2014

    • Author(s)
      猪狩 公宏, 工藤 敏文, 中村 政宏, 葛井 総太郎, 西澤 真人, 内山 英俊, 小泉 伸也, 豊福 崇浩, 地引 政利, 井上 芳徳
    • Organizer
      第114回日本外科学会総会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2014-04-03 – 2014-04-05
    • Related Report
      2014 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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