Optimal timing of Clopidogrel cessation before cardiac surgeries assessed by VerifyNow system.
| Project/Area Number |
24592077
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 血小板 / 血小板機能 / 心臓手術 / 出血量 / 硫酸クロピドグレル / チエノピリジン / 抗血小板剤 / VerifyNowシステム / クロピドグレル / 術前血小板機能 / 術後出血量 / 抗血小板薬 / 国際情報交換 |
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| Outline of Final Research Achievements |
The optimal timing of Clopidogrel cessation was studied by means of the VerifyNow platelet function evaluation system. The platelet function had already recovered above cut-off line by 3-5 days after stopping Clopidogrel. The interval, fourteen days, which was recommended in the ‘instruction for use’, can be shortened after this research results.
The postoperative drainage volume was higher in cases with low preoperative platelet function with no statistical significance.
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Report
(5 results)
Research Products
(10 results)
