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Basic scientific research for the clinical diagnostic imaging of parametric X-ray

Research Project

Project/Area Number 24592844
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionNihon University

Principal Investigator

KANEDA Takashi  日本大学, 松戸歯学部, 教授 (40185947)

Co-Investigator(Kenkyū-buntansha) OGURA Ichiro  日本歯科大学, 新潟生命歯学部, 准教授 (30349972)
OKADA Hiroyuki  日本大学, 松戸歯学部, 教授 (70256890)
MORI Shintaro  日本大学, 松戸歯学部, 講師 (40419792)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
KeywordsパラメトリックX線 / 位相コントラストイメージング / X線吸収端 / 画像診断 / 医療応用 / パラメトリックエックス線 / パラメトリックX線
Outline of Final Research Achievements

Parametric radiation based X-ray (PXR), one of the pioneering studies using accelerator, is studied and expected for a kind of new X-ray source. In the Laboratory for Electron Beam Research and Application institute of quantum science (LEBRA). The purpose of this study was to evaluate the potential of LEBRA- parameteric X-ray as a new X-ray source for diagnostic imaging.
Compared to conventional X-ray, LEBRA-PXR images showed contrast related to different wavelengths, reflecting histological differences between tissues. Comparing histological findings, malignant tumor images with LEBRA-PXR revealed more clearly than that of conventional X-ray image. Using LEBRA-PXR, nearly perfect monochromatic X-ray source imaging, the images of malignant tumor displayed different contrasts from conventional X-ray. LEBRA-PXR produce a useful diagnostic imaging tool as a new X-ray source.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (22 results)

All 2016 2015 2014 2013 2012 Other

All Journal Article (8 results) (of which Peer Reviewed: 4 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (14 results)

  • [Journal Article] <b>Preliminary Clinical Application Study of Parametric X-rays in Diagnostic Imaging </b>2015

    • Author(s)
      Kaneda T,Sekiya K, Suemitsu M, Sakae T, Hayakawa Y, Kawashima Y, Hirahara N, Muraoka H, Ito K, Muramatsu T, Ishida M, Okada H
    • Journal Title

      International Journal of Oral-Medical Sciences

      Volume: 14 Issue: 1 Pages: 8-12

    • DOI

      10.5466/ijoms.14.8

    • NAID

      130005099989

    • ISSN
      1347-9733, 2185-4254
    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Basic study of parametric X-ray radiation for clinical diagnosis using 125MeV linear particle accelerator2015

    • Author(s)
      Okada H, Kaneda T,Sekiya K, Kawashima Y, Suemitsu M, Hayakawa Y, Sakae T.
    • Journal Title

      J Hard Tissue Biology

      Volume: 24 Issue: 3 Pages: 299-302

    • DOI

      10.2485/jhtb.24.299

    • NAID

      130005088093

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Element-sensitive computed tomography by fine tuning of PXR-based X-ray source2015

    • Author(s)
      Hayakawa Y, Hayakawa K, Inagaki M, Kaneda T, Nakao K, Nogami K, Sakae T, Sakai T, Sato I, Takahashi Y, Tanaka T.
    • Journal Title

      Nucl. Instr. and Meth. B

      Volume: 355 Pages: 251-256

    • DOI

      10.1016/j.nimb.2015.03.010

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical application of parameteric X-ray in diagnostic imaging: Preliminary study2014

    • Author(s)
      Kaneda T, Kawashima Y, Sasaki Y, Suemitsu M, Okada H, Hayakawa Y,Sakae T, Muraoka H, Hirahara N
    • Journal Title

      Journal of Oral snd Maxillofacial Surgery

      Volume: 72

    • Related Report
      2014 Research-status Report
  • [Journal Article] The clinical application of the LEBRA-PXR in imaging diagnosis.2013

    • Author(s)
      Kotaro Sekiya, Takashi Kaneda, Shintaro Mori, Masaaki Suemitsu, Yasushi Hayakawa, Toshiro Sakae.
    • Journal Title

      Key Engineering Materials.

      Volume: 529-530 Pages: 317-320

    • Related Report
      2013 Research-status Report
  • [Journal Article] Computed Tomography for Light Materials Using a Monochromatic X-ray Beam Produced by Parametric X-ray Radiation2013

    • Author(s)
      Yasushi Hayakawa, Yumiko Takahashi, et. al.
    • Journal Title

      Nucl. Instrum. Methods Phys. Res., Sect. B

      Volume: 309 Pages: 230-236

    • DOI

      10.1016/j.nimb.2013.01.025

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] The clinical application of the LEBRA-PXR in imaging diagnosis.2013

    • Author(s)
      Kotaro Sekiya, Takashi Kaneda, Shintaro Mori, Masaaki Suemitsu, Yasushi Hayakawa, Toshiro Sakae.
    • Journal Title

      Key Engineering Materials

      Volume: 529-530 Pages: 317-320

    • Related Report
      2012 Research-status Report
  • [Journal Article] Computed tomography for light materials using a monochromatic X-ray beam produced by parametric X-ray radiation2013

    • Author(s)
      Hayakawa Y, Hayakawa K, Inagaki M, Kaneda T, Nakao K, Nogami K, Sakae T, Sakai T, Sato I, Takahashi Y.
    • Journal Title

      Nuclear Instruments and Methods B

      Volume: 10 Pages: 1-5

    • Related Report
      2012 Research-status Report
  • [Presentation] テラヘルツコヒーレント光の 画像診断への臨床応用: 臨床応用への基礎実験2016

    • Author(s)
      川島雄介、金田 隆
    • Organizer
      LEBRAユーザーズミーティング
    • Place of Presentation
      日本大学理工学部船橋キャンパス テクノプレース15 (千葉県船橋市)
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] Element-sensitive computed tomography using fine tenability of PXR-based X-ray source2014

    • Author(s)
      Hayayakawa Y, Hayakawa K, Inagaki M, Kaneda T, Nakao K, Nogami K, Sakae T, Sakai T, Sato I, Takahashi Y, Tanaka T.
    • Organizer
      The 6th International conference &#8211; channeling 2014 Charged & Neutral Particles channeling phenomena
    • Place of Presentation
      Capri, Italy
    • Year and Date
      2014-10-05 – 2014-10-10
    • Related Report
      2014 Research-status Report
  • [Presentation] Clinical application of parameteric X-ray in diagnostic imaging: Preliminary study2014

    • Author(s)
      Kaneda T, Kawashima Y, Sasaki Y, Suemitsu M, Okada H, Hayakawa Y, Sakae T, Muraoka H, Hirahara N
    • Organizer
      96th Annual Meeting, Scientific Sessions and Exhibition, American Association of Oral and Maxillofacial Surgeons
    • Place of Presentation
      Honolulu, U.S.A
    • Year and Date
      2014-09-07 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Presentation] LEBRA-PXRの幾何学的特徴2014

    • Author(s)
      川島雄介,末光正昌,佐々木悠介,早川恭史,村松輝晃,平原尚久,村岡宏隆,福田大河,金田 隆
    • Organizer
      第55回日本歯科放射線学会学術大会
    • Place of Presentation
      タワーホール船堀、東京
    • Year and Date
      2014-06-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Monochromatic imaging with parametric X-ray: A basic study.2013

    • Author(s)
      Sekiya K, Kaneda T, Suemitsu M, Hayakawa Y, Sakae T
    • Organizer
      The 51th Annual Meeting American Society of Neuroradiology
    • Place of Presentation
      San Diego, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] LEBRAパラメトリックX線を用いた画像診断に関する基礎的検討2013

    • Author(s)
      金田 隆,関谷浩太郎,川島雄介,村松輝晃,末光正昌,寒河江登志朗,早川恭史,佐々木悠介,宇田川勇,岡田裕之
    • Organizer
      第54回日本歯科放射線学会総会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] LEBRA-PXRの画像診断への応用:幾何学的特徴の検討2013

    • Author(s)
      川島雄介,関谷浩太郎,佐々木悠介,村松輝晃,平原尚久,村岡宏隆,福田大河,金田隆,早川恭史,近藤信太郎
    • Organizer
      第54回日本歯科放射線学会総会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] Clinical application of parametric radiation based X-ray (PXR): Preliminary study2013

    • Author(s)
      Kotaro Sekiya, Takashi Kaneda, Masaaki Suemitsu, Yasushi Hayakawa, Toshiro Sakae, Yusuke Kawashima, Teruaki Muramatsu,
    • Organizer
      The 19th International Congress of Dento-Maxillo-Facilal Radiology
    • Place of Presentation
      Bergen, Norway
    • Related Report
      2013 Research-status Report
  • [Presentation] LEBRAパラメトリックエックス線の画像診断への応用2012

    • Author(s)
      関谷浩太郎,金田 隆,末光正昌,寒河江登志朗,森進太郎,関谷恵子,早川恭史,桑田隆生,岡田裕之,山本浩嗣
    • Organizer
      第53回日本歯科放射線学会総会
    • Place of Presentation
      いわて県民情報交流センター(岩手)
    • Related Report
      2012 Research-status Report
  • [Presentation] LEBRAパラメトリックX線を用いた位相コントラスト・イメージング:基礎的検討2012

    • Author(s)
      金田 隆,関谷浩太郎,末光正昌,寒河江登志朗,森進太郎,関谷恵子,早川恭史,桑田隆生,岡田裕之,山本浩嗣
    • Organizer
      第53回日本歯科放射線学会総会
    • Place of Presentation
      いわて県民情報交流センター(岩手)
    • Related Report
      2012 Research-status Report
  • [Presentation] LEBRA-PXRを線源とした画像診断の可能性:基礎的研究2012

    • Author(s)
      関谷浩太郎,金田 隆,森進太郎,末光正昌,原 武史,早川恭史,寒河江登志朗
    • Organizer
      第48回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Related Report
      2012 Research-status Report
  • [Presentation] A Basic Study of Parametric Radiation based X-ray for Clinical Diagnosis using 125MeV Linear Particle Accelerator2012

    • Author(s)
      Kotaro Sekiya, Takashi Kaneda, Masaaki Suemitsu, Yasushi Hayakawa, Toshiro Sakae
    • Organizer
      The 46th Annual Meeting American Society of Head & Neck Radiology
    • Place of Presentation
      the Eden Roc Renaissance Miami Beach.Florida, USA,
    • Related Report
      2012 Research-status Report
  • [Presentation] The Clinical Application of the LEBRA-PXR in Imaging Diagnosis.2012

    • Author(s)
      Kotaro Sekiya, Takashi Kaneda, Shintaro Mori, Masaaki Suemitsu, Yasushi Hayakawa, Toshiro Sakae.
    • Organizer
      Bioceramics 24
    • Place of Presentation
      The Kyushu University School of Medicine Centennial Hall .Fukuoka, Japan
    • Related Report
      2012 Research-status Report
  • [Presentation] LEBR-PXRを線源に用いた悪性腫瘍の画像診断への応用:基礎的検討

    • Author(s)
      関谷浩太郎,末光正昌,金田 隆,寒河江登志朗,森進太郎,関谷恵子,村松輝晃,川島雄介,伊東浩太郎,今井浩之,徳永悟士,原慶宜,宇田川勇,桑田隆生,岡田裕之,山本浩嗣
    • Organizer
      第12回日本大学口腔科学会学術大会
    • Place of Presentation
      日本大学松戸歯学部(千葉)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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