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Fundamental study on the modulation mechanism of orofacial pain by the taste and olfactory sensations and its application to clinical use.

Research Project

Project/Area Number 24593053
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Surgical dentistry
Research InstitutionNiigata University

Principal Investigator

TANAKA Yutaka  新潟大学, 医歯学総合病院, 講師 (50323978)

Co-Investigator(Kenkyū-buntansha) SEO Kenji  新潟大学, 医歯学系, 教授 (40242440)
TERUMITSU Makoto  新潟大学, 医歯学系, 准教授 (60401767)
YAMAMURA Kensuke  新潟大学, 医歯学系, 教授 (90272822)
KURATA Shigenobu  新潟大学, 医歯学系, 助教 (20464018)
YOSHIKAWA Hiroyuki  新潟大学, 医歯学総合病院, 医員 (20547575)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords口腔顔面痛 / 慢性疼痛 / 味覚刺激 / 嗅覚刺激 / 疼痛変調機構 / 歯科心身症
Outline of Final Research Achievements

The aim of this study was to examine the possibility of reduction of orofacial pain and to investigate the modulation mechanism of orofacial pain by the taste and olfactory stimulation.The subjects of this study were patients with chronic orofacial pain that treaded in our department.All the subjects underwent gustatory test and olfactometric tests,and were evaluated with self-answerd type pain score(VAS), various psychological tests, autonomic activity analysis, and near-infrared spectroscopy.As a result, in all the subjects, orofacial pain intensity didn’t change by olfactory test. On the other hand, gustatory test by sweet taste decreased pain intensity(VAS)transient in the glossalgia patients.This study suggest that the sweet taste stimulation may have a transient pain reduction mechanism of glossalgia among orofacial pain.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2015 2014 2013 2012

All Presentation (7 results)

  • [Presentation] PHQ-9を用いた口腔顔面痛患者の心身医学的検証2015

    • Author(s)
      田中 裕, 村松芳幸, 瀬尾憲司
    • Organizer
      日本慢性疼痛学会
    • Place of Presentation
      ローズホテル横浜(神奈川県横浜市)
    • Year and Date
      2015-02-27 – 2015-02-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Patient Health Questionnaire(PHQ-9, PHQ-15)を用いた口腔顔面痛患者の心身医学的検証2014

    • Author(s)
      田中 裕, 村松芳幸, 村松公美子, 真島一郎, 藤村健夫, 清水夏恵, 清野 洋, 吉嶺文俊, 櫻井浩治, 瀬尾憲司
    • Organizer
      日本心療内科学
    • Place of Presentation
      東京国際交流館・プラザ平成(東京都江東区)
    • Year and Date
      2014-11-29 – 2014-11-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 口腔顔面領域の病態が健康関連QOLに及ぼす影響の検討2014

    • Author(s)
      田中 裕,照光 真,弦巻 立,倉田行伸,瀬尾憲司
    • Organizer
      日本歯科麻酔学会
    • Place of Presentation
      日本歯科大学新潟生命歯学部(新潟県新潟市)
    • Year and Date
      2014-10-10 – 2014-10-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] 口腔顔面痛における抑うつ傾向の調査2014

    • Author(s)
      田中 裕, 村松芳幸, 村松公美子, 真島一郎, 藤村健夫, 清水夏恵, 清野 洋, 吉嶺文俊, 櫻井浩治, 瀬尾憲司
    • Organizer
      日本心身医学会
    • Place of Presentation
      幕張メッセ国際会議場(千葉県千葉市)
    • Year and Date
      2014-06-06 – 2014-06-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] 口腔顔面痛患者に対する心身医学的検証2013

    • Author(s)
      田中 裕, 瀬尾憲司, 村松芳幸, 村松公美子, 他
    • Organizer
      第54回日本心身医学会総会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2013 Research-status Report
  • [Presentation] SF-8を用いた慢性疼痛を有する歯科心身症患者の健康関連QOLの検討2013

    • Author(s)
      田中 裕, 瀬尾憲司, 村松芳幸, 村松公美子, 他
    • Organizer
      第18回日本心療内科学会総会
    • Place of Presentation
      愛知県名古屋市
    • Related Report
      2013 Research-status Report
  • [Presentation] 精神疾患簡易構造化面接法を用いた口腔および顔面領域に対する疼痛患者の心身医学的アプローチ2012

    • Author(s)
      田中 裕, 瀬尾憲司, 村松芳幸, 村松公美子
    • Organizer
      第27回日本歯科心身医学会
    • Place of Presentation
      埼玉県川越市
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2025-11-19  

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