Dose distribution during stereotactic body radiotherapy using volumetric modulated arc therapy

• Project/Area Number: 24601005
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: 医学物理学・放射線技術学
• Research Institution: The University of Tokyo
• Principal Investigator: IMAE Toshikazu 東京大学, 医学部附属病院, 診療放射線技師 (80420222)
• Co-Investigator(Renkei-kenkyūsha): NAKAGAWA Keiichi 東京大学, 医学部附属病院, 准教授 (80188896) ; YAMASHITA Hideomi 東京大学, 医学部附属病院, 講師 (70447407) ; HAGA Akihiro 東京大学, 医学部附属病院, 助教 (30448021) ; TAKENAKA Shigeharu 東京大学, 医学部附属病院, 診療放射線技師 (10623564)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 強度変調回転照射法 / 体幹部定位放射線治療 / 治療中 / 対象内構造 / 実線量分布 / 定位放射線治療 / 体幹部 / 強度変調法 / 回転型 / 線量分布 / 回転型強度変調法

Outline of Final Research Achievements

Volumetric modulated arc therapy (VMAT) is capable of acquiring respiratory signals derived from projection images and machine parameters based on logs during VMAT delivery. The purpose of this study was to reconstruct the dose distribution during stereotactic body radiotherapy (SBRT) using VMAT. The present method successfully reconstructed the dose distribution using the respiratory signals and machine parameters acquired during treatment. This is a feasible method for verifying the actual dose distribution for a moving target.

Research Products

• [Journal Article] 肺定位放射線治療中の呼吸信号および照射制御パラメータを用いた線量分布の再構成 (2014)
  • Author(s): 今江禄一，芳賀昭弘，早乙女直也，木田智士，中野正寛，竹中重治，竹内幸浩，白木尚，矢野敬一，山下英臣，中川恵一，大友邦．
  • Journal Title: 日本放射線技術学会雑誌 Volume: 70(11) Pages: 1225-1234
  • NAID: 130004713495
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Volumetric modulated arc therapy for lung stereotactic radiation therapy can achieve high local control rates. (2014)
  • Author(s): Yamashita H, Haga A, Takahashi W, Takenaka R, Imae T, Takenaka S, Nakagawa K.
  • Journal Title: Radiation Oncology Volume: 9 Issue: 1 Pages: 243-243
  • DOI: 10.1186/s13014-014-0243-1
  • Peer Reviewed / Open Access
• [Journal Article] Independent absorbed-dose calculation using the Monte Carlo algorithm in volumetric modulated arc therapy. (2014)
  • Author(s): Haga A, Magome T, Takenaka S, Imae T, Sakumi A, Nomoto A, Igaki H, Shiraishi K, Yamashita H, Ohtomo K, Nakagawa K.
  • Journal Title: Radiattion Oncology Volume: 9 Issue: 1 Pages: 1-9
  • DOI: 10.1186/1748-717x-9-75
  • Peer Reviewed / Open Access
• [Journal Article] 回転照射法を用いたWinston-Lutzテストおよび幾何学的補正テーブルの取得 (2014)
  • Author(s): 今江 禄一，芳賀 昭弘，早乙女 直也，竹中 重治，岡野 由香里，佐々木 克剛，根津 誠，三枝 茂輝，白木 尚，矢野 敬一，中川 恵一，大友 邦．
  • Journal Title: 日本放射線技術学会雑誌 Volume: In press
  • NAID: 130003393506
  • Peer Reviewed
• [Journal Article] 逐次近似再構成方法による4次元Cone beamCT画質改善． (2013)
  • Author(s): 木田智士，増谷佳孝，中野正寛，今江禄一，芳賀昭弘．
  • Journal Title: 電子情報通信学会技術研究報告 Volume: 112 Pages: 73-75
• [Journal Article] 肺定位放射線治療中における標的の移動量の評価 (2012)
  • Author(s): 今江禄一，芳賀昭弘，木田智士，早乙女直也，白木尚，矢野敬一，中川恵一，篠原広行．
  • Journal Title: Med Imag Tech Volume: 30(5) Pages: 262-267
  • NAID: 130002573587
  • Peer Reviewed
• [Journal Article] In-treatment 4D cone-beam CT with image-based respiratory phase recognition (2012)
  • Author(s): Kida S, Masutani Y, Yamashita H, Imae T, Matsuura T, Saotome N, Ohtomo K, Nakagawa K, Haga A
  • Journal Title: Radiological Physics and Technology Volume: 25 Issue: 2 Pages: 1-9
  • DOI: 10.1007/s12194-012-0146-5
  • Peer Reviewed
• [Journal Article] 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy. (2012)
  • Author(s): Nakagawa K
  • Journal Title: J Radiat Res. Volume: 53(4) Issue: 4 Pages: 628-32
  • DOI: 10.1093/jrr/rrs013
  • Peer Reviewed
• [Presentation] Dose distribution using respiratory signals and machine parameters during treatment. (2014)
  • Author(s): T Imae, A Haga , N Saotome , S Kida , M Nakano , Y Takeuchi , T Shiraki , K Yano , H Yamashita , K Nakagawa , K Ohtomo.
  • Organizer: The American Association of Physicists in Medicine
  • Place of Presentation: Austin, U.S.A.
  • Year and Date: 2014-07-20 – 2014-07-24
• [Presentation] Delivered 4D Dose Calculation for Lung-VMAT Patients Using In-Treatment CBCT and LINAC Log Data (2014)
  • Author(s): N Saotome, A Haga , T Imae , S Kida , M Nakano , H Yamashita , K Nakagawa , K Ohtomo.
  • Organizer: The American Association of Physicists in Medicine
  • Place of Presentation: Austin, U.S.A.
  • Year and Date: 2014-07-20
• [Presentation] VMATを用いた体幹部定位放射線治療中の線量評価 (2014)
  • Author(s): 今江禄一，芳賀昭弘，早乙女直也，白木尚，矢野敬一，山下英臣，中川恵一，大友邦．
  • Organizer: 第70回日本放射線技術学会総会学術大会
  • Place of Presentation: 横浜
  • Year and Date: 2014-04-12
• [Presentation] Registration Accuracy with Four‐Dimensional Cone‐Beam CT for Lung Cancer Treatment (2013)
  • Author(s): A Haga, J Kotoku, S Kida, Y Masutani, H Yamashita, W Takahashi, T Imae, K Nakagawa
  • Organizer: American Association of Physicists in Medicine
  • Place of Presentation: Indiana police, U.S.A
• [Presentation] Accuracy comparison of 3D and 4D CBCT based lung tumor registrations by way in-treatment 4D CBCT analysis (2013)
  • Author(s): K. Nakagawa, A. Haga, W. Takahashi, H. Yamashita, T. Imae, S. Kida, Y. Masutani, A. Sakumi, K. Ohtomo
  • Organizer: 2nd ESTRO Forum
  • Place of Presentation: Geneva, Switzerland
• [Presentation] Verification System for Image-Guided Radiation Therapy by Using In-Treatment 4D CBCT (2013)
  • Author(s): W. Takahashi, A. Haga, N. Yamamoto, H. Yamashita, T. Imae, S. Kida, A. Sakumi, K. Ohtomo, T. Kamada, K. Nakagawa.
  • Organizer: 2nd ESTRO Forum
  • Place of Presentation: Geneva, Switzerland
• [Presentation] 繰り返し再構成によるCone-beam CT の画質改善 (2012)
  • Author(s): 木田智士，芳賀昭弘，増谷佳孝，早乙女直也，中野正寛，作美明，今江禄一，山下英臣，中川恵一．
  • Organizer: 第104回医学物理学会学術大会
  • Place of Presentation: つくば
• [Presentation] 回転照射法を用いたWinston-Lutzテストおよび幾何学的補正テーブルの取得．
  • Author(s): 今江禄一，芳賀昭弘，竹中重治，根津誠，白木尚，矢野敬一，中川恵一．
  • Organizer: 第69回日本放射線技術学会総会学術大会．
  • Place of Presentation: 横浜
• [Presentation] 治療計画用4D-CT画像を用いた肺腫瘍の体幹部定位放射線治療(SBRT)の線量評価
  • Author(s): 三枝茂輝，芳賀昭弘，今江禄一，佐々木克剛，白木尚，矢野敬一，中川恵一．
  • Organizer: 第69回日本放射線技術学会総会学術大会．
  • Place of Presentation: 横浜
• [Presentation] ポータルイメージングシステムを用いた強度変調放射線治療における線量検証．
  • Author(s): 竹中重治，芳賀昭弘，今江禄一，岡野由香里，白木尚，矢野敬一，中川恵一．
  • Organizer: 第69回日本放射線技術学会総会学術大会
  • Place of Presentation: 横浜
• [Presentation] 治療中の呼吸信号および照射制御パラメータを用いた線量分布の構築
  • Author(s): 今江禄一，芳賀昭弘，早乙女直也，岡野由香里，兼子芳浩，根津誠，三枝茂輝，白木尚，矢野敬一，中川恵一，大友邦．
  • Organizer: 日本放射線腫瘍学会第26回学術大会
  • Place of Presentation: 青森
• [Presentation] 逐次近似再構成方法による4次元Cone beam CTの画質改善
  • Author(s): 木田智士，増谷佳孝，中野正寛，早乙女直也，今江禄一，中川恵一，芳賀昭弘．
  • Organizer: 第105回医学物理学会学術大会
  • Place of Presentation: 横浜
• [Presentation] The characteristics of EPID for in-vivo dosimetry
  • Author(s): Naoya Saotome, Satoshi Kida, Toshikazu Imae, Katsutake Sasaki, Yoshitaka Matsutani, Akihiro Haga, Keiichi Nakagawa.
  • Organizer: American Association of Physicists in Medicine
  • Place of Presentation: Indiana police, U.S.A
• [Presentation] The characteristics of EPID for in-vivo dosimetry
  • Author(s): Naoya Saotome, Satoshi Kida, Toshikazu Imae, Katsutake Sasaki, Yoshitaka Matsutani, Akihiro Haga, Keiichi Nakagawa.
  • Organizer: 第105回日本医学物理学会学術大会
  • Place of Presentation: 横浜
• [Presentation] 治療同時4D-CBCTによるVMAT- 体幹部定位放射線治療の治療位置精度評価
  • Author(s): 佐々木克剛，白木尚，今江禄一，矢野敬一，芳賀昭弘，岡野由香里，根津誠．
  • Organizer: 第68回日本放射線技術学会総会学術大会
  • Place of Presentation: 横浜
• [Presentation] VMAT（Volumetric Modulated Arc Therapy）におけるモンテカルロ治療計画装置を用いた独立線量検証方法の検討
  • Author(s): 竹中重治，芳賀昭弘，今江禄一，佐々木克剛，三枝茂輝，白木尚，矢野敬一．
  • Organizer: 第68回日本放射線技術学会総会学術大会
  • Place of Presentation: 横浜
• [Presentation] 放射線治療時の照射野外臓器における線量評価
  • Author(s): 白木尚，三枝茂輝，根津誠，今江禄一，矢野敬一，作美明．
  • Organizer: 第68回日本放射線技術学会総会学術大会
  • Place of Presentation: 横浜
• [Remarks] 東京大学医学部附属病院 放射線科 放射線治療部門 > 研究・業績
  • URL: http://www.u-tokyo-rad.jp/works/index.html
• [Remarks] 東京大学医学部附属病院 放射線科 放射線治療部門 > 研究・業績
  • URL: http://www.u-tokyo-rad.jp/works/index.html
• [Remarks] 東京大学医学部附属病院 放射線科 放射線治療部門 > 研究・業績
  • URL: http://www.u-tokyo-rad.jp/works/index.html