Construction of cooperating peptide probes for tumor detection
| Project/Area Number |
24650649
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical oncology
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| Research Institution | Japanese Foundation for Cancer Research |
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Principal Investigator |
MATSUMURA Sachiko 公益財団法人がん研究会, がん研究所, 特任研究員 (90414052)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | がん / ペプチド / リガンド / ナノバイオ / 癌 / 蛍光イメージング / 分子認識 |
|---|
| Outline of Final Research Achievements |
The aim of this work is to construct peptide probes that use a cooperative interaction of molecules containing ligands on cells. Peptides with a ligand sequence were assembled to form a nano-sized structure. The assemblage containing many ligand peptides specifically bound to tumor cells that expressed the target proteins.
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Report
(4 results)
Research Products
(2 results)
