Development of nuclear decontamination procedures using a novel algal strain, Parachlorella sp binos, and its application to reduction of thyroid cancer risk
| Project/Area Number |
24651074
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental technology/Environmental materials
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| Research Institution | Fukushima Medical University (2013-2014)
University of Yamanashi (2012) |
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Principal Investigator |
SHIMURA HIROKI 福島県立医科大学, 医学部, 教授 (40303416)
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| Co-Investigator(Kenkyū-buntansha) |
FURUYA Fumihiko 山梨大学, 医学部第三内科, 講師 (90456450)
一條 昌志 山梨大学, 総合研究部, 助教 (50436854)
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| Co-Investigator(Renkei-kenkyūsha) |
ICHIJO Masashi 山梨大学, 医学部第三内科, 助教 (50436854)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 放射性物質 / 除染 / 微細緑藻類 / 甲状腺癌 / 活性酸素 / RhoB / 甲状腺ホルモン受容体 / 徐染 |
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| Outline of Final Research Achievements |
We found that a novel algal strain, Parachlorella sp binos, uptakes radioactive iodine and radioactive cations such as cesium, and strontium, which were leaked from the Fukushima Dai-ichi Nuclear Power Plant. High-resolution secondary ion mass spectrometry (SIMS) showed a localization of accumulated iodine and cations in the cytosol, and the extracellular matrix, respectively. In addtion, radioiodine was actively uptaked in the presence of superoxide generated by the photosynthesis. At present, the decontamination method using this algal strain is used for decontamination of the environment of Fukushima Prefecture.
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Report
(4 results)
Research Products
(64 results)
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[Journal Article] Effects of 3,3',5-triiodothyronine on microglial functions2015
Author(s)
Mori Y, Tomonaga D, Kalashnikova A, Furuya F, Akimoto N, Ifuku M, Okuno Y, Beppu K, Fujita K, Katafuchi T, Shimura H, Churilov LP, Noda M
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Journal Title
Glia
Volume: 63(5)
Issue: 5
Pages: 906-920
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Thyroid ultrasound findings in a follow-up survey of children from three Japanese prefectures: Aomori, Yamanashi, and Nagasaki2015
Author(s)
Naomi Hayashida, Misa Imaizumi, Hiroki Shimura, Fumihiko Furuya, Noriyuki Okubo, Yasushi Asari, Takeshi Nigawara, Sanae Midorikawa, Kazuhiko Kotani, Shigeyuki Nakaji, Akira Ohtsuru, Takashi Akamizu, Masafumi Kitaoka, Shinichi Suzuki, Nobuyuki Taniguchi, Shunichi Yamashita & Noboru Takamura
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Journal Title
SCIENTIFIC REPORTS
Volume: 5
Issue: 1
Pages: 9046-9046
DOI
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Neutrophil gelatinase-associated lipocalin levels associated with cardiovascular disease in chronic kidney disease patients.2014
Author(s)
Furuya F, Shimura H, Yokoichi H, Takahashi K, Akiyama D, Asakawa C, Okamura A, Motosugi A, Haraguchi K, Yamagata Z, Kobayashi T.
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Journal Title
Clin Exp Nephrol.
Volume: 18
Issue: 5
Pages: 778-83
DOI
Related Report
Peer Reviewed
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[Presentation] Preliminary Results in Prevalence of Thyroid Hemiagenesis and Hypoplasia: The Fukushima Health Survey2015
Author(s)
Satoshi Suzuki, Satoru Suzuki, Sanae Midorikawa, Toshihiko Fukushima, Hiroki Shimura, Tetsuya Ohira, Akira Ohtsuru, Masafumi Abe, Izumi Nakamura, Shunichi Yamashita and Shinichi Suzuki
Organizer
THE ENDOCRINE SOCIETY'S 97TH ANNUAL MEETING & EXPO
Place of Presentation
San diego, California
Year and Date
2015-03-06
Related Report
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[Presentation] Systematic Determination of Thyroid Volume By Ultrasound Examination from the Infant to Adolescence in Japan: The Fukushima Health Management Survey2015
Author(s)
Izumi Nakamura, Satoru Suzuki, Sanae Midorikawa, Toshihiko Fukushima, Hiroki Shimura, Tetsuya Ohira, Akira Ohtsuru, Masafumi Abe, Yoshisada Shibata, Satoshi Suzuki, Shunichi Yamashita and Shinichi Suzuki
Organizer
THE ENDOCRINE SOCIETY'S 97TH ANNUAL MEETING & EXPO
Place of Presentation
San diego, California
Year and Date
2015-03-05
Related Report
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[Presentation] B-Mode Ultrasonography Is a Predictor of Progression to Thyroid Dysfunction: A Prospective Study2014
Author(s)
Hiroki Shimura, Asako Miyazaki, Katsumi Taki, Fumihiko Furuya, Kazuyasu Ohta, Masato Ikeda, Kazutaka Haraguchi, Toyoshi Endo, Masahiro Takusagawa, Yuiko Ozaki, Shinichi Suzuki, Nobuhiro Fukunari, Masashi Kitaoka and Tetsuro Kobayashi
Organizer
ICE-ENDO 2014 THE ENDOCRINE SOCIETY'S 96th ANNUAL MEETING & EXPO
Place of Presentation
Chicago, USA
Year and Date
2014-06-23
Related Report
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