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Development of program to enhance speech fluency of stuttering: Integration of neuroscientific understanding and therapy methods

Research Project

Project/Area Number 24680025
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Sensitivity informatics/Soft computing
Research InstitutionGunma University (2013-2016)
Tokyo Denki University (2012)

Principal Investigator

Toyomura Akira  群馬大学, 保健学研究科, 講師 (90421990)

Project Period (FY) 2012-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥26,910,000 (Direct Cost: ¥20,700,000、Indirect Cost: ¥6,210,000)
Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Keywords吃音 / 脳機能計測 / 機能的磁気共鳴画像法 / 事象関連電位 / 聴覚フィードバック / 発話流暢性 / マインドフルネス / 有症率 / 情動 / fMRI / 脳波 / 発症率 / 神経メカニズム / 流暢性促進 / 対面会話 / 対面発話 / 四肢の運動 / 発話運動制御
Outline of Final Research Achievements

This study investigated behavioral and neurological aspects of stuttering, and aimed to seek evidence-based treatments based on the understanding of mechanisms of stuttering. Eight-week practice using metronome sound had induced significant change of activity in the basal ganglia during speech production. The occurrence of stuttering under face-to-face condition was found to be related to the activity in the limbic system (amygdala). The speech performance under the delayed auditory feedback condition was related to the auditory evoked potential induced by the delayed auditory feedback sound. The auditory feedback perception was suggested to change by longitudinal mindfulness meditation practice. Rate of stuttering at 3 years of age was investigated in Japanese children. 1.4% of the children showed stuttering and 83% of them recovered.

Report

(6 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (29 results)

All 2017 2016 2015 2014 2013 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (27 results) (of which Int'l Joint Research: 1 results,  Invited: 4 results)

  • [Journal Article] Fluctuation of Lower Limb Movement in the MRI Bore: Different Contributions of the Cortical and Subcortical Locomotor Regions2017

    • Author(s)
      Toyomura A, Yokosawa K, Kuriki S
    • Journal Title

      Advanced Biomedical Engineering

      Volume: 6 Issue: 0 Pages: 15-20

    • DOI

      10.14326/abe.6.15

    • NAID

      130005402002

    • ISSN
      2187-5219
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effect of an 8-week practice of externally triggered speech on basal ganglia activity of stuttering and fluent speakers2015

    • Author(s)
      Toyomura A., Fujii T., Kuriki S.
    • Journal Title

      NeuroImage

      Volume: 109 Pages: 458-468

    • DOI

      10.1016/j.neuroimage.2015.01.024

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 口唇運動の模倣に関与する神経機構の検討2017

    • Author(s)
      豊村暁,藤井哲之進,栗城眞也
    • Organizer
      日本音響学会2017年春季研究発表会
    • Place of Presentation
      川崎市
    • Year and Date
      2017-03-15
    • Related Report
      2016 Annual Research Report
  • [Presentation] 吃音のメカニズムに関する研究の紹介2016

    • Author(s)
      豊村暁
    • Organizer
      北見吃音サロン「なんだろう?吃音 ~早期発見と早期支援の必要性,社会的支援の意義を考える」
    • Place of Presentation
      北見市
    • Year and Date
      2016-10-15
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Fluctuation of lower limb movement in the MRI Bore: Different contributions of the cortical and subcortical locomotor region.2016

    • Author(s)
      Toyomura A, Yokosawa K, Kuriki S
    • Organizer
      生体医工学シンポジウム2016
    • Place of Presentation
      旭川市
    • Year and Date
      2016-09-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] 遅延聴覚フィードバック音声に対する聴覚誘発電位の測定方法についての検討2016

    • Author(s)
      豊村暁, 宮代大輝, 栗城眞也
    • Organizer
      第4回吃音・流暢性障害学会
    • Place of Presentation
      所沢市
    • Year and Date
      2016-09-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] ヒトを対象とした神経科学研究の最前線2015

    • Author(s)
      豊村暁
    • Organizer
      群馬大学医理工GFL企画先端研究学際講演会
    • Place of Presentation
      群馬大学(桐生市)
    • Year and Date
      2015-12-22
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 吃音について2015

    • Author(s)
      豊村暁
    • Organizer
      前橋市ことばを育てる親の会
    • Place of Presentation
      前橋市総合福祉会館(前橋市)
    • Year and Date
      2015-12-07
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 遅延聴覚フィードバック音声に対する事象関連電位の測定2015

    • Author(s)
      豊村暁,栗城眞也
    • Organizer
      計測自動制御学会システム・情報部門学術講演会
    • Place of Presentation
      函館アリーナ(函館市)
    • Year and Date
      2015-11-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] 機能的磁気共鳴画像法を用いた吃音話者の神経活動の特徴2015

    • Author(s)
      豊村暁
    • Organizer
      日本吃音・流暢性障害学会第3回大会シンポジウム「吃音の脳研究の最前線」
    • Place of Presentation
      大阪保健医療大学(大阪市)
    • Year and Date
      2015-08-29
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 吃音と判断する閾値と有症率の関係についての考察2015

    • Author(s)
      豊村暁、島田美智子、鎌田美鈴、小松友紀恵、船橋ひづる、木内瑞穂、小野栄治、藤井哲之進、南孝輔
    • Organizer
      日本吃音・流暢性障害学会第3回大会
    • Place of Presentation
      大阪保健医療大学(大阪市)
    • Year and Date
      2015-08-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] 離島地区における3歳児の吃音有症率調査について2015

    • Author(s)
      島田美智子、豊村暁、鎌田美鈴、小松友紀恵、船橋ひづる、関いづみ、小野栄治、藤井哲之進、南孝輔
    • Organizer
      日本吃音・流暢性障害学会第3回大会
    • Place of Presentation
      大阪保健医療大学(大阪市)
    • Year and Date
      2015-08-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] Neural activity elicited by context-dependent speech dysfluency2015

    • Author(s)
      Toyomura A., Fujii T., Yokosawa K., Kuriki S.
    • Organizer
      8th World Congress on Fluency Disorders
    • Place of Presentation
      リスボン(ポルトガル)
    • Year and Date
      2015-07-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 吃音者が他者と会話する際の脳活動計測の試み2014

    • Author(s)
      豊村暁,藤井哲之進,横澤宏一,栗城眞也
    • Organizer
      第2 回吃音・流暢性障害学会
    • Place of Presentation
      目白大学
    • Year and Date
      2014-08-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 対面・非対面会話時の神経活動の計測2014

    • Author(s)
      豊村暁,藤井哲之進,横澤宏一,栗城眞也
    • Organizer
      第53 回日本生体医工学会大会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2014-06-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] Neural correlates of stuttering under external rhythm and face-to-face communication2014

    • Author(s)
      Toyomura A., Fujii T., Yokosawa K., Kuriki S
    • Organizer
      OHBM 2014 Annual Meeting
    • Place of Presentation
      CCH-Congress Center in Hamburg (Hamburg)
    • Year and Date
      2014-06-11 – 2014-06-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] 家庭で言語指導を行う保護者の吃音に対する態度の変化2014

    • Author(s)
      藤井哲之進,南孝輔,島田美智子,豊村暁
    • Organizer
      第40回日本コミュニケーション障害学会学術講演会
    • Place of Presentation
      金沢大学
    • Year and Date
      2014-05-10 – 2014-05-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Neural correlates of stuttering under external rhythm and face-to-face communication2014

    • Author(s)
      Akira Toyomura, Tetsunoshin Fujii, Koichi Yokosawa, Shinya Kuriki
    • Organizer
      The 20th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      Germany
    • Related Report
      2013 Annual Research Report
  • [Presentation] 対面・非対面会話時の神経活動の計測2014

    • Author(s)
      豊村暁,藤井哲之進,横澤宏一,栗城眞也
    • Organizer
      第53回日本生体医工学会大会
    • Place of Presentation
      仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 家庭で言語指導を行う保護者の吃音に対する態度の変化2014

    • Author(s)
      藤井哲之進,南孝輔,島田美智子,豊村暁
    • Organizer
      第40回日本コミュニケーション障害学会学術講演会
    • Place of Presentation
      金沢
    • Related Report
      2013 Annual Research Report
  • [Presentation] 乳幼児健診における吃音児の割合2013

    • Author(s)
      島田美智子,藤井哲之進,南孝輔,豊村暁
    • Organizer
      第14回日本言語聴覚学会
    • Place of Presentation
      札幌
    • Related Report
      2013 Annual Research Report
  • [Presentation] リッカムプログラムにより吃症状が改善した子の事例2013

    • Author(s)
      藤井哲之進,南孝輔,島田美智子,豊村暁
    • Organizer
      第39回日本コミュニケーション障害学会学術講演会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 3 歳児健診における吃音児の統計調査2013

    • Author(s)
      島田美智子,藤井哲之進,南孝輔,豊村暁
    • Organizer
      第1回日本吃音・流暢性障害学会
    • Place of Presentation
      金沢
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effect of external pacing on speech motor control : MEG/fMRI studies2012

    • Author(s)
      Akira Toyomura, Koichi Yokosawa, Tetsunoshin Fujii, Shinya Kuriki
    • Organizer
      The 18th International Conference on Biomagnetism
    • Place of Presentation
      France at Maison de la Chimie (Paris)
    • Year and Date
      2012-08-28
    • Related Report
      2012 Annual Research Report
  • [Presentation] 長期の発話流暢性促進の訓練を受けた吃音児の音声の変化2012

    • Author(s)
      藤井哲之進, 豊村暁
    • Organizer
      日本音響学会聴覚研究会
    • Place of Presentation
      北海道医療大学札幌サテライトキャンパス(札幌市)
    • Year and Date
      2012-07-19
    • Related Report
      2012 Annual Research Report
  • [Presentation] Neural plasticity of stuttering speakers by rhythmical speech training2012

    • Author(s)
      Akira Toyomura, Tetsunoshin Fujii, Shinya Kuriki
    • Organizer
      The 18th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      China National Convention Center (Beijing)
    • Year and Date
      2012-06-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] 非流暢性発話の運動制御に関する脳機能計測2012

    • Author(s)
      豊村暁, 藤井哲之進, 横澤宏一, 栗城眞也
    • Organizer
      第27回日本生体磁気学会大会
    • Place of Presentation
      東京電機大学(東京都)
    • Year and Date
      2012-06-01
    • Related Report
      2012 Annual Research Report
  • [Presentation] 日本語を母語とする吃音児を対象としたリッカムプログラムの適用2012

    • Author(s)
      藤井哲之進, 南孝輔, 島田美智子, 豊村暁
    • Organizer
      第38回日本コミュニケーション障害学会学術講演会
    • Place of Presentation
      県立広島大学(三原市)
    • Year and Date
      2012-05-12
    • Related Report
      2012 Annual Research Report
  • [Presentation] 両手指協調運動に見られる吃音者と非吃音者のパフォーマンスの違い2012

    • Author(s)
      藤井哲之進, 豊村暁, 島田美智子, 南孝輔
    • Organizer
      第38回日本コミュニケーション障害学会学術講演会
    • Place of Presentation
      県立広島大学(三原市)
    • Year and Date
      2012-05-12
    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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