Regulation of axial stem cells deriving neural plate cells and mesoderm cells
| Project/Area Number |
24687029
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Developmental biology
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| Research Institution | The University of Tokushima (2013-2015)
Osaka University (2012) |
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Principal Investigator |
TKEMOTO Tatsuya 徳島大学, 藤井節郎記念医科学センター, 助教 (30443899)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥27,430,000 (Direct Cost: ¥21,100,000、Indirect Cost: ¥6,330,000)
Fiscal Year 2014: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Fiscal Year 2013: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
Fiscal Year 2012: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Keywords | 細胞運命 / 転写制御 / 細胞分化 / Wntシグナル / 体軸幹細胞 |
|---|
| Outline of Final Research Achievements |
1. I have studied the relationship between the intensity of Wnt signal and the cell fate of axial stem cells.
2. I have identified the culture condition to derive axial stem cells from epiblast stem cells, and analyzed the difference of expression patterns.
3. I have established a new method to generate genetically modified mouse using CRISPR/Cas9 system.
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Report
(5 results)
Research Products
(16 results)
