The effect of carnosic acid on cancer induced by psychological stress

Research Project

Project/Area Number	24700832
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Eating habits, studies on eating habits
Research Institution	Saga University
Principal Investigator	KAYASHIMA Tomoko 佐賀大学, 文化教育学部, 准教授 (90452599)
Project Period (FY)	2012-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	カルノシン酸 / 精神的ストレス / 血管新生 / ガン / ローズマリー / 卵巣腫瘍 / ストレス / 卵巣腫瘍細胞 / ノルエピネフリン / カルノソール / ストレスホルモン / 血管内皮細胞
Outline of Final Research Achievements	In this study, the effect of carnosic acid from rosemary leaves on cancer induced by psychological stress was examined using ovarian cancer cells. Carnosic acid suppressed cell growth and VEGF mRNA and protein expressions induced by norepinephrin. These results suggest that carnosic acid may be useful for cancer treatment through inhibition of angiogenesis that is important target of cancer induced by psychological stress.

Report

(4 results)