Possibility of the whole body supply of hydrogen formed in large intestine and the nutritional role
Project/Area Number |
24700835
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Nayoro City University |
Principal Investigator |
TANABE Hiroki 名寄市立大学, 保健福祉学部, 助教 (60573920)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | 栄養学 / 動物 / 発酵 / 水素ガス |
Research Abstract |
The aim of this study is to clarify that a part of hydrogen derived from large intestine moved to the organs of the whole body and supplied hydrogen contributed to reduce the oxidation stress of whole bodies such as the obesity. At first we analyzed biodistribution of hydrogen derived from large intestine and found that hydrogen concentration in portal blood, liver, perirenal fat, epididimal fat rose. In addition, we proposed that it could not supply hydrogen to all organs only by the course through the portal vein. We examined the influence that a genetic background to cause the obesity of the hereditary obesity model mouse gave for hydrogen and hydrogen large intestine generation due to fructan was stronger than a wild type mouse and clarified that it was guided.
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Report
(3 results)
Research Products
(10 results)