| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Research Abstract |
Ceramide kinase produces the bioactive lipid ceramide-1-phosphate and appears as a key enzyme for regulating cell growth and arachidonic acid metabolism. In this study, to elucidate a novel physiological function, we focused on the transport of intracellular cholesterol. We showed that ceramide kinase is a negative regulator of the cholesterol transport from late endosomes to endoplasmic reticulum.
|
