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Population based reference birth weights and risk factors for neonatal death in Japanese singletons and twins

Research Project

Project/Area Number 24790612
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Public health/Health science
Research InstitutionNational Research Institute for Child Health and Development (2013)
The University of Tokyo (2012)

Principal Investigator

OTA Erika  独立行政法人国立成育医療研究センター, その他部局等, その他 (40625216)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords低出生体重児 / 母子保健 / 疫学 / 疫学研究 / 人口動態 / 低出生体重 / 出生体重標準曲線 / 早期新生児死亡 / 双胎 / 単胎
Research Abstract

This study aimed to construct population-based singleton and twin birthweight reference curves, and to identify the risk factors relating to early- and neonatal death. For the birthweight reference, birthweight from birth registry data for 2008-2010 was tabulated by gestational week, and a reference curve calculated using smoothed b-splines. To assess risk factors for early- and neonatal death, multilevel Poisson regression was performed, adjusting for gestational age, maternal age, parity, sex, and birthweight discordance for twins.
The birthweight reference curve developed in this study should be used for twins in clinical settings. Young mothers (under 20 years old for singletons and under 25 years old for twins ), babies delivered before the 25th week of gestational age, and as a twin-specific factor pairs with large birthweight difference within the pairs or SGA-concordant pairs for are at high risk for early neonatal mortality.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (10 results)

All 2014 2013 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (9 results)

  • [Journal Article] Risk Factors of Pre-Eclampsia/Eclampsia and Its Adverse Outcomes in Low- and Middle-Income Countries: A WHO Secondary Analysis.2014

    • Author(s)
      Bilano VL, Ota E, Ganchimeg T, Mori R, Souza JP
    • Journal Title

      PLoS ONE

      Volume: 9(3) Issue: 3 Pages: 91198-91198

    • DOI

      10.1371/journal.pone.0091198

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 1979から2010年における日本全出生の低出生体重児および早産増加の要因分析2014

    • Author(s)
      大田えりか、米岡大輔、野内英樹、森臨太郎
    • Organizer
      第24回日本疫学会学術総会
    • Place of Presentation
      宮城県
    • Year and Date
      2014-01-24
    • Related Report
      2013 Final Research Report
  • [Presentation] 低出生体重児出生を予防するための妊娠中の栄養介入に関するオーバービューレビュー2013

    • Author(s)
      大田えりか,森臨太郎
    • Organizer
      第28回日本国際保健医療学会学術大会
    • Place of Presentation
      沖縄
    • Year and Date
      2013-11-03
    • Related Report
      2013 Final Research Report
  • [Presentation] Pre-eclapmsia risk factors and adverse outcomesin low- and middle income countries : A WHO secondary analysis2013

    • Author(s)
      Ota E, Bilano VL,Togoobaatar G, Mori R, Souza JP
    • Organizer
      The 23rd Asian & Oceanic Congress of Obstetrics & Gynaecology
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2013-10-22
    • Related Report
      2013 Final Research Report
  • [Presentation] 2008−2010年の日本全国における双胎児の出生時体重基準曲線と早期新生児の死亡のリスク因子に関する研究2013

    • Author(s)
      宮本かりん,大田えりか
    • Organizer
      日本助産学会
    • Place of Presentation
      金沢
    • Year and Date
      2013-05-02
    • Related Report
      2013 Final Research Report
  • [Presentation] 2008-2010年の日本全国における双胎児の出生時体重基準曲線2013

    • Author(s)
      宮本かりん、大田えりか
    • Organizer
      日本助産学会
    • Place of Presentation
      金沢21世紀美術館 (石川県金沢市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 2008-2010年の日本全国における双胎児の出生時体重基準曲線と生後1年未満の死亡のリスク因子 に関する研究

    • Author(s)
      宮本かりん、大田えりか
    • Organizer
      日本助産学会
    • Place of Presentation
      金沢
    • Related Report
      2013 Annual Research Report
  • [Presentation] 1979年から2010年における日本全出生の 低出生体重児および早産増加の要因分析

    • Author(s)
      大田えりか
    • Organizer
      日本疫学会
    • Place of Presentation
      仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 低出生体重児出生を予防するための妊娠中の栄養介入に関するオーバービューレビュー

    • Author(s)
      大田えりか
    • Organizer
      国際保健医療学会
    • Place of Presentation
      沖縄、明桜大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] Pre-eclapmsia risk factors and adverse outcomesin low- and middle income countries: A WHO secondary analysis.

    • Author(s)
      大田えりか
    • Organizer
      The 23rd Asian & Oceanic Congress of Obstetrics & Gynaecology
    • Place of Presentation
      タイ、バンコク
    • Related Report
      2013 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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