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Melanocyte behaviors in C57BL/6 nu/nu mice

Research Project

Project/Area Number 24791166
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dermatology
Research InstitutionNagoya City University

Principal Investigator

KATO HIROSHI  名古屋市立大学, 医学(系)研究科(研究院), 研究員 (30570709)

Research Collaborator NAKAMURA Motoki  
TAGUCHI Osamu  
MORITA Akimichi  
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsmelanocyte / melanoblast / C57B/L6 / ヌードマウス / 分化 / 誘導 / メラノブラスト / メラノサイト / C57BL/6 / mouse
Outline of Final Research Achievements

The skin color of mammal was made by color from the pigment called melanin. Melanocyte was the cell that produces melanin. In the mouse, melanocytes didn’t migrate into the skin, but into hairs. C57BL/6 nude was the black and hairless mouse. At birth, the skin color of this mouse was white. As the body grows, it changed into black and decolorized with weeks. We researched the differentiation and migration of the melanocyte with this mouse. The melanocytes which were not able to migrate into hairs, maturated in the skin and became apoptic death. These immature melanocytes had migratory ability into other tissue.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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