Analysis of Sirt3 Gene and Mitochondrial Genome in Japanese Patients with Presbycusis

Research Project

Project/Area Number	24791803
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Otorhinolaryngology
Research Institution	Iwate Medical University
Principal Investigator	OHTSUKA Hisashi 岩手医科大学, 医学部, 助教 (80453299)
Project Period (FY)	2012-04-01 – 2014-03-31
Project Status	Completed (Fiscal Year 2013)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords	老人性難聴 / ミトコンドリア / Sirt3
Research Abstract	We found statistically significant associations in patients with presbycusis and in individuals with normal hearing. These data suggest that SIRT3 and IDH2 have the potential to be predisposing factors that can lead to presbycusis in the Japanese population.

Report

(3 results)