| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
To investigate the proteins related to bone resorption around implants caused by occlusal force, the rat implant occlusion model which the author developed before was used as the first step to prevent clinical bone resorption in future. Two kinds of implant abutment were used. One was cantilever type which caused bone resorption that eventually resulted in destruction of ossseointegration. The other was round shape type which did not caused bone resorption around the implants. Under these two different types of occlusion, the bone around implant displayed different histological reactions and some proteins which might cause the bone resorption under occlusal force were detected.
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