Budget Amount *help |
¥212,940,000 (Direct Cost: ¥163,800,000、Indirect Cost: ¥49,140,000)
Fiscal Year 2017: ¥23,270,000 (Direct Cost: ¥17,900,000、Indirect Cost: ¥5,370,000)
Fiscal Year 2016: ¥26,130,000 (Direct Cost: ¥20,100,000、Indirect Cost: ¥6,030,000)
Fiscal Year 2015: ¥37,180,000 (Direct Cost: ¥28,600,000、Indirect Cost: ¥8,580,000)
Fiscal Year 2014: ¥53,560,000 (Direct Cost: ¥41,200,000、Indirect Cost: ¥12,360,000)
Fiscal Year 2013: ¥72,800,000 (Direct Cost: ¥56,000,000、Indirect Cost: ¥16,800,000)
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Outline of Final Research Achievements |
We have examined the molecular basis of the long longevity of reproductive castes of social insects (termite kings and queens, and honeybee queens) and obtained the following results. 1) We identified caste-, sex- and age-specific expression of chemoreceptor genes, immune-related genes, DNA-repairing genes and epigenetic modification genes by performing a transcriptome analysis of all castes of the termite Reticulitermes speratus. 2) We found antioxidant enzymes including catalase, peroxiredoxin and superoxide dismutase underling the efficient antioxidant system of a long-lived termite queen. 3) We identified uric acid as an important antioxidant compound in termite workers. 4) We demonstrated that parental phenotypes influence the social status of offspring through genomic imprinting in termites. 5) We found that heterochromatinization through histone modification and effective energy metabolism using beta oxidation of fatty acids are related to the long longevity of honeybee queens.
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