Study on element-sensitive tomography using parametric X-ray radiation

• Project/Area Number: 25286087
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Quantum beam science
• Research Institution: Nihon University
• Principal Investigator: HAYAKAWA Yasushi 日本大学, 理工学部, 教授 (40307799)
• Co-Investigator(Kenkyū-buntansha): KANEDA Takashi 日本大学, 歯学部, 教授 (40185947) ; TAKAHASHI Yumiko 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 研究員 (70339258) ; SAKAI Takeshi 日本大学, 理工学部, 助手 (20409147)
• Co-Investigator(Renkei-kenkyūsha): SAKAE Toshiro 日本大学, 歯学部, 教授 (20112948)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000); Fiscal Year 2015: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2014: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000); Fiscal Year 2013: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
• Keywords: 量子ビーム測定手法 / PXR / 単色X線 / CT / 元素分析 / 量子ビーム

Outline of Final Research Achievements

Detecting a three-dimensional (3D) distribution of a specific element has been experimentally demonstrated using the parametric X-ray (PXR) source at Nihon University. Based on the K-shell edge subtraction (KES) method, the 3D-distributions of Sr element in the samples were obtained as computed tomography (CT) images. First, 2-color CT experiments were independently carried out at the X-ray energies above and below the Sr K-shell absorption edge using tunability of the PXR source. The Sr distribution was obtained from the subtraction between these CT images. Next, the experiment for simultaneous KES-CT was performed using dual-energy crossing beams based on the spectral property of the PXR beam. The result shows that the Sr distribution can be obtained by this unique method.

Research Products

• [Journal Article] Element-sensitive computed tomography by fine tuning of PXR-based X-ray source (2015)
  • Author(s): Hayakawa Y, Hayakawa K, Inagaki M, Kaneda T, Nakao K, Nogami K, Sakae T, Sakai T, Sato I, Takahashi Y, Tanaka T.
  • Journal Title: Nucl. Instr. and Meth. B Volume: 355 Pages: 251-256
  • DOI: 10.1016/j.nimb.2015.03.010
  • Peer Reviewed
• [Journal Article] <b>Preliminary Clinical Application Study of Parametric X-rays in Diagnostic Imaging </b> (2015)
  • Author(s): Kaneda T,Sekiya K, Suemitsu M, Sakae T, Hayakawa Y, Kawashima Y, Hirahara N, Muraoka H, Ito K, Muramatsu T, Ishida M, Okada H
  • Journal Title: International Journal of Oral-Medical Sciences Volume: 14 Issue: 1 Pages: 8-12
  • DOI: 10.5466/ijoms.14.8
  • NAID: 130005099989
  • ISSN: 1347-9733, 2185-4254
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Basic study of parametric X-ray radiation for clinical diagnosis using 125MeV linear particle accelerator (2015)
  • Author(s): Okada H, Kaneda T,Sekiya K, Kawashima Y, Suemitsu M, Hayakawa Y, Sakae T.
  • Journal Title: J Hard Tissue Biology Volume: 24 Issue: 3 Pages: 299-302
  • DOI: 10.2485/jhtb.24.299
  • NAID: 130005088093
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] X-ray Imaging Based on Small-angle X-ray Scattering Using Spatial Coherence of Parametric X-ray Radiation (2014)
  • Author(s): Y. Hayakawa, K. Hayakawa, M. Inagaki, T. Kaneda, K. Nakao, K. Nogami, T. Sakae, T. Sakai, I. Sato, Y. Takahashi, T. Tanaka
  • Journal Title: Journal of Physics: Conference Series Volume: 517 Pages: 0120171-6
  • DOI: 10.1088/1742-6596/517/1/012017
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Clinical application of parameteric X-ray in diagnostic imaging: Preliminary study (2014)
  • Author(s): T. Kaneda, Y. Kawashima , Y. Sasaki , M. Suemitsu , H. Okada , Y. Hayakawa , T. Sakae , H. Muraoka , N. Hirahara
  • Journal Title: Journal of Oral and Maxillofacial Surgery Volume: 72 Issue: 9 Pages: e173-e174
  • DOI: 10.1016/j.joms.2014.06.312
• [Journal Article] X-ray imaging using a tunable coherent X-ray source based on parametric X-ray radiation (2013)
  • Author(s): Yasushi Hayakawa, Yumiko Takahashi, et. al.
  • Journal Title: Journal of Instrumentation Volume: 8 Issue: 08 Pages: 1-13
  • DOI: 10.1088/1748-0221/8/08/c08001
  • Peer Reviewed
• [Journal Article] Design Optimization of 100 Kv DC Gun Wehnelt Electrode for FEL Linac at LEBRA (2013)
  • Author(s): T. Sakai, K. Hayakawa, Y. Hayakawa, M. Inagaki, K. Nakao, K. Nogami, T. Tanaka
  • Journal Title: Proceedings of FEL2013 (The 35th International Free-Electron Laser Conference) (August 26-30, 2013, New York, USA) Volume: Web Pages: 387-390
• [Journal Article] Monochromatic imaging with parametric X-ray: A basic study (2013)
  • Author(s): Sekiya K, Kaneda T, Suemitsu M, Hayakawa Y, Sakae T
  • Journal Title: Proceeding of the 51th Annual Meeting American Society of Neuroradiology Volume: Web
  • Peer Reviewed
• [Presentation] 角度分解トポグラフィーと局所ロッキングカーブ法によるAlイオン注入SiC基 板の歪状態の観察 (2016)
  • Author(s): 高橋 由美子
  • Organizer: 第63回応用物理学会春季学術講演会
  • Place of Presentation: 東京工業大学大岡山キャン パス (東京都目黒区)
  • Year and Date: 2016-03-19
• [Presentation] Novel Imaging Techniques Using an Exotic X-Ray Source with Spatial Chirp (2016)
  • Author(s): Y. Hayakawa
  • Organizer: The 10th Asian Meeting on Biomedical Synchrotron Radiation Imaging (AMSI2015)
  • Place of Presentation: 山形大学医学部 (山形県山形市)
  • Year and Date: 2016-02-19
  • Int'l Joint Research
• [Presentation] SiC基板の角度分解トポグラフィーによる評価 (2016)
  • Author(s): 高橋 由美子
  • Organizer: 第29回日本放射光学会年会・合同シンポジウム
  • Place of Presentation: 東京大学柏の葉 キャンパス駅前サテライト (千葉県柏市)
  • Year and Date: 2016-01-09
• [Presentation] Dual energy computed tomography for element analysis based on K-shell absorption edge using the LEBRA PXR (2015)
  • Author(s): Y. Hayakawa
  • Organizer: MASR 2015 (8th International Symposium on Medical Applications of Synchrotron Radiation)
  • Place of Presentation: Villard de Lans, France
  • Year and Date: 2015-10-05
  • Int'l Joint Research
• [Presentation] Project on the superposition of beamlines for parametric X-ray radiation and coherent transition radiation in the THz region at LEBRA (2015)
  • Author(s): Y. Hayakawa
  • Organizer: The XI International Symposium "Radiation from Relativistic Electrons in Periodic Structures" (RREPS-15)
  • Place of Presentation: Saint Petersburg, Russia
  • Year and Date: 2015-09-06
  • Int'l Joint Research / Invited
• [Presentation] Element-sensitive Computed Tomography by Fine Tuning of PXR-based X-ray Source (2014)
  • Author(s): Y. Hayakawa, K. Hayakawa, M. Inagaki, T. Kaneda, K. Nakao, K. Nogami, T. Sakae, T. Sakai, I. Sato, Y. Takahashi, T. Tanaka
  • Organizer: The 6 th International Conference Channeling 2014 - Charged & Neutral Particles Channeling Phenomena
  • Place of Presentation: Capri (イタリア)
  • Year and Date: 2014-10-05 – 2014-10-10
• [Presentation] Clinical application of parameteric X-ray in diagnostic imaging: Preliminary study (2014)
  • Author(s): Kaneda T, Kawashima Y, Sasaki Y, Suemitsu M, Okada H, Hayakawa Y, Sakae T, Muraoka H, Hirahara N
  • Organizer: 96th Annual Meeting, Scientific Sessions and Exhibition, American Association of Oral and Maxillofacial Surgeons
  • Place of Presentation: Honolulu (米国)
  • Year and Date: 2014-09-07 – 2014-09-12
• [Presentation] エネルギー回収型クライオ電子リニアックを基盤とするコンパクト空間干渉X線源: X線放射源の基本設計 (2014)
  • Author(s): 早川 恭史,佐藤 勇,竹中 久貴,玄 知奉,遠藤 克己
  • Organizer: 第11回日本加速器学会年会
  • Place of Presentation: 青森市文化会館 (青森)
  • Year and Date: 2014-08-09 – 2014-08-11
• [Presentation] LEBRA-PXRの幾何学的特徴 (2014)
  • Author(s): 川島雄介，末光正昌，佐々木悠介，早川恭史，村松輝晃，平原尚久，村岡宏隆，福田大河，金田隆
  • Organizer: 第55回日本歯科放射線学会学術大会
  • Place of Presentation: タワーホール船堀 (東京)
  • Year and Date: 2014-06-09
• [Presentation] PXR円錐ビームを用いた極小角散乱イメージング (2014)
  • Author(s): 早川恭史
  • Organizer: 第20回FELとHigh-Power Radiation研究会
  • Place of Presentation: 日本大学理工学部 (東京)
• [Presentation] X-ray Imaging Based on Small-angle X-ray Scattering Using Spatial Coherence of Parametric X-ray Radiation (2013)
  • Author(s): Y. Hayakawa, K. Hayakawa, M. Inagaki, T. Kaneda, K. Nakao, K. Nogami, T. Sakae, T. Sakai, I. Sato, Y. Takahashi, T. Tanaka
  • Organizer: The X International Symposium "Radiation from Relativistic Electrons in Periodic Structures" (RREPS-13)
  • Place of Presentation: Lake Sevan (アルメニア)
  • Invited
• [Presentation] 2結晶型パラメトリックX線源におけるダイヤモンド単結晶の試験 (2013)
  • Author(s): 早川 恭史，雫石 崇，石橋 直也，早川 建，稲垣 学，中尾 圭佐，野上 杏子，境 武志，佐藤 勇，田中 俊成
  • Organizer: 第10回日本加速器学会年会
  • Place of Presentation: 名古屋大学豊田講堂 (名古屋)
• [Presentation] Design Optimization of 100 Kv DC Gun Wehnelt Electrode for FEL Linac at LEBRA (2013)
  • Author(s): 境 武志，田中 俊成，早川 建，早川 恭史，中尾 圭佐，野上 杏子，稲垣 学
  • Organizer: FEL 2013 (The 35th International Free Electron Laser Conference)
  • Place of Presentation: New York (米国)
• [Presentation] Monochromatic imaging with parametric X-ray: A basic study (2013)
  • Author(s): Sekiya K, Kaneda T, Suemitsu M, Hayakawa Y, Sakae T
  • Organizer: The 51th Annual Meeting American Society of Neuroradiology
  • Place of Presentation: San Diego (米国)
• [Presentation] LEBRAパラメトリックＸ線を用いた画像診断に関する基礎的検討 (2013)
  • Author(s): 金田 隆，関谷浩太郎，川島雄介，村松輝晃，末光正昌，寒河江登志朗，早川恭史， 佐々木悠介，宇田川勇，岡田裕之
  • Organizer: 第54回日本歯科放射線学会総会
  • Place of Presentation: 福岡県立ももち文化センター(博多)
• [Presentation] LEBRA-PXRの画像診断への応用：幾何学的特徴の検討 (2013)
  • Author(s): 川島雄介，関谷浩太郎，佐々木悠介，村松輝晃，平原尚久，村岡宏隆，福田大河，金田隆，早川恭史，近藤信太郎
  • Organizer: 第54回日本歯科放射線学会総会
  • Place of Presentation: 福岡県立ももち文化センター(博多)