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rapid screening of anti-allergic substances in vegetables and fruits and evaluation of it during cooking process

Research Project

Project/Area Number 25350096
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits
Research InstitutionKagawa University

Principal Investigator

Tamura Hirotoshi  香川大学, 農学部, 教授 (00188442)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords抗アレルギー活性 / QuEChERS / サツマイモ / 玉ねぎ / 調理効果 / 抗アレルギー成分 / QuEChERS法 / フラボノイド類 / ミント / ケルセチン-4'-グルコシド / 活性相関 / RBL-2H3 細胞 / QuEChERS簡易抽出法 / アレルギー抑制成分
Outline of Final Research Achievements

For rapid screening of anti-allergic substances from edible plants, QuEChERS method for extraction and Peason's correlation coefficient for selection of important target compounds were newly developed. Using these kinds of new techniques, sweet potatoes, Naruto kintoki, and onions were found to have great activities. Quercetin 4’-glucoside was responsible for anti-allergy of onions. During cooking of onions and sweet potatoes, Anti-allergy activity did not decrease. Moreover, in some cases, activity was increased during the processing and boiling. These results indicate the importance of cooking process in our daily life and also useful evidence for reduction of chemical drugs and keeping of our healthy life.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (10 results)

All 2016 2015 2014 Other

All Int'l Joint Research (1 results) Journal Article (6 results) (of which Peer Reviewed: 5 results,  Open Access: 4 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Int'l Joint Research] 浙江工商大学(中国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Antiallergic activity of rosmarinic acid esters is modulated by hydrophobicity, and bulkiness of alkyl side chain2015

    • Author(s)
      Fengxian ZHU, Zhongming XU, Ronghua YANG, Lina YONEKURA, Hirotoshi TAMURA
    • Journal Title

      Biochemistry, Biotechnology and Biosciences

      Volume: 79(7) Issue: 7 Pages: 1178-1182

    • DOI

      10.1080/09168451.2015.1010478

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] High antiallergic activity of 5,6,4'-trihydroxy-7,8,3'-trimethoxyflavone and 5,6-dihydroxy-7,8,3',4'-tetramethoxyflavone from Eau de Cologne mint (Mentha × piperita citrata)2015

    • Author(s)
      Akihiko Sato, Hirotoshi Tamura
    • Journal Title

      Fitoterapia

      Volume: 102 Pages: 74-83

    • DOI

      10.1016/j.fitote.2015.02.003

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Antiallergic activities of eleven onions (Allium cepa) were attributed to quercetin 4'-glucoside using QuEChERS method and Pearson's correlation coefficient2015

    • Author(s)
      Akihiko Sato, Ting Zhang, Lina Yonekura, Hirotoshi Tamura
    • Journal Title

      Journal of Functional Foods

      Volume: 14 Pages: 581-589

    • DOI

      10.1016/j.jff.2015.02.029

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Secoiridoid Type of Antiallergic Substances in the Pomace, Wasting Materials in Three Varieties of Japanese Olive (Olea europaea)2014

    • Author(s)
      Akihiko Sato, Noboru Shinozaki and Hirotoshi Tamura
    • Journal Title

      J. Agric. Food Chem., 62(31), 7787-7795 (2014).

      Volume: 62(31) Issue: 31 Pages: 7787-7795

    • DOI

      10.1021/jf502151b

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] ANTIALLERIC ACTIVITY OF VARIOUS KINDS OF VEGETABLES AND FRUITS IN JAPAN AND THAILAND2014

    • Author(s)
      Akihiko Sato, Vipa Surojanametakul, Ting Zhang, Sayuri Tanaka, Shiori Okabe, Lina Yonekura, Toshiya Masuda, Warunee Varanyanond, Hirotoshi Tamura
    • Journal Title

      Journal of Science and Technology (Vietnam Academy of Science and Technology),

      Volume: 52(B) Pages: 726-735

    • Related Report
      2014 Research-status Report
  • [Journal Article] Rosmarinic Acid Extract for Antioxidant, Antiallergic and α-Glucosidase Inhibitory Activities, Isolated by Supramolecular Technique and Solvent Extraction from Perilla Leaves,2014

    • Author(s)
      Fengxian Zhu, Takayuki Asada, Akihiko Sato, Yoriko Koi, Hisashi Nishiwaki, and Hirotoshi Tamura
    • Journal Title

      Journal of Agricultural and. Food Chemistry

      Volume: 62 Issue: 4 Pages: 885-892

    • DOI

      10.1021/jf404318j

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] A role of phytochemicals in foods in aging society2016

    • Author(s)
      Hirotoshi Tamura
    • Organizer
      FOOD INNOVATION ASIA CONFERENCE 2016. Food Research and Innovation for Sustainable Global Prosperity
    • Place of Presentation
      Bangkok
    • Year and Date
      2016-06-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ロズマリン酸ヘキシル化体のα-グルコシダーゼ阻害活性と抗菌活性に関する研究2015

    • Author(s)
      朱鳳仙,徐忠明,西脇寿,高野隼人,米倉リナ,楊栄華,田村啓敏
    • Organizer
      日本食品科学工学会2015年度大会
    • Place of Presentation
      京都
    • Year and Date
      2015-08-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] Antialleric activity of various kinds of vegetables and fruits in Japan and Thailand2014

    • Author(s)
      179)Akihiko Sato, Vipa Surojanametakul, Ting Zhang, Sayuri Tanaka, Shiori Okabe, Lina Yonekura, Toshiya Masuda, Warunee Varanyanond and Hirotoshi Tamura
    • Organizer
      2014 International symposium on Natural products R & D
    • Place of Presentation
      Da Lat, Vietnam
    • Year and Date
      2014-11-14 – 2014-11-15
    • Related Report
      2014 Research-status Report
    • Invited

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Published: 2014-07-25   Modified: 2022-02-07  

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