Development and evaluation of tricalcium phosphate-based ceramic material having osteogenesis promoting action
| Project/Area Number |
25350554
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Chiba Institute of Technology |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | バイオセラミックス / リン酸三カルシウム / 生体吸収性材料 / 置換固溶体 / β型リン酸三カルシウム / 生体必須元素 |
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| Outline of Final Research Achievements |
In this study, Ca site (cation site) in β type tricalcium phosphate (β-TCP) was substituted to monovalent， divalent or trivalent metal ions using a living body essential element and P site (anion site) was simultaneously substituted to various oxyacid salt ions． The obtained substituted solid solution was established the manufacturing method of the sintering body. In addition, the obtained sintering bodies were evaluated for solubility using various solution, for the interaction with the osteoblasts and the osteoclast cell.
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Report
(4 results)
Research Products
(33 results)
