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Association between the genetic polymorphism and judo performance

Research Project

Project/Area Number 25350783
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Sports science
Research InstitutionTokai University

Principal Investigator

Agemizu Kenichiro  東海大学, 体育学部, 准教授 (40439659)

Co-Investigator(Kenkyū-buntansha) MACHIDA SHUICHI  順天堂大学, 大学院スポーツ健康科学研究科, 先任准教授 (40421226)
ARUGA SEIJI  東海大学, スポーツ医科学研究所, 教授 (90287037)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords遺伝子多型 / 柔道 / 競技力 / 形態測定 / 体力測定 / 階級 / アスリート遺伝子 / 肥満遺伝子 / 体組成 / トレーニング科学 / 武道
Outline of Final Research Achievements

The purpose of this study was to investigate the association between gene polymorphisms and judo status, body composition and muscle strength in judo athletes.
The subjects in the present study were 216 male judo athletes. Genotyping by PCR-RFLP was used to detect alpha-actinin-3 (ACTN3), Angiotensin-converting enzyme (ACE) and Insulin-like growth factor 2 (IGF2) gene polymorphisms. They were divided into three groups based on their results in national or international competitions. Body composition and muscle strength were measured. The results indicate that the IGF2 gene polymorphism may be associated with judo status. Moreover, IGF2 and ACTN3 gene polymorphisms are associated with muscle strength in judo athletes.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (16 results)

All 2016 2015 2014 2013 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 3 results,  Open Access: 1 results) Presentation (12 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] The combination of insulin-like growth factor 2, alpha-actinin-3, and angiotensin-converting enzyme gene polymorphisms in judo athletes: a pilot study2016

    • Author(s)
      Itaka T, Agemizu K, Aruga S, Machida S
    • Journal Title

      Juntendo Medical Journal

    • NAID

      130005865685

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Judo status is not associated with ACE I/D polymorphism in Japanese judo athletes2016

    • Author(s)
      Itaka T, Agemizu K, Aruga S, Machida S
    • Journal Title

      Archives of Budo

      Volume: 12 Pages: 61-67

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The G allele of the IGF2 ApaI polymorphism is associated with judo status2016

    • Author(s)
      Itaka T, Agemizu K, Aruga S, Machida S
    • Journal Title

      Journal of Strength and Conditioning Research

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Interleukin-6-induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting2013

    • Author(s)
      Kurosaka M, Machida S.
    • Journal Title

      Cell proliferation

      Volume: 46 Issue: 4 Pages: 365-373

    • DOI

      10.1111/cpr.12045

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 柔道競技力を規定する候補遺伝子の探索-CNTF、CNTFR、IL15Ra遺伝子の検討-2015

    • Author(s)
      位髙駿夫,上水研一朗,有賀誠司,町田修一
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館・ホテルアパローム紀の国(和歌山県・和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] Association between the combination of ACTN3, ACE, IGF2 gene polymorphisms and judo status.2015

    • Author(s)
      Itaka T, Agemizu K, Aruga S, Machida S.
    • Organizer
      The 2nd Congress, International Academy of Sportology
    • Place of Presentation
      順天堂大学本郷キャンパス有山登記念館講堂(順天堂大学・文京区)
    • Year and Date
      2015-09-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 柔道選手の筋力のトレーナビリティとACTN3遺伝子多型の関連性について2015

    • Author(s)
      上水研一朗,位髙駿夫,有賀誠司,町田修一
    • Organizer
      日本武道学会第48回大会
    • Place of Presentation
      日本体育大学世田谷キャンパス(東京都・世田谷区)
    • Year and Date
      2015-09-09
    • Related Report
      2015 Annual Research Report
  • [Presentation] Association between the IGF2/ACE genotype combination and judo status2015

    • Author(s)
      Itaka T, Agemizu K, Aruga S, Machida S.
    • Organizer
      20th annual Congress of the European College of Sports Science
    • Place of Presentation
      Clarion Hotel & Congress Malmo Live (Malmo,Sweden)
    • Year and Date
      2015-06-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] IGF2は柔道競技レベルを規定するアスリート遺伝子2014

    • Author(s)
      位高駿夫, 上水研一朗, 有賀誠司, 町田修一
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎県・長崎市)
    • Year and Date
      2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 日本人男子柔道トップアスリートの脱共役タンパク質遺伝子多型の特徴2014

    • Author(s)
      高木香奈, 位高駿夫, 上水研一朗, 有賀誠司, 町田修一
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学(長崎県・長崎市)
    • Year and Date
      2014-09-21
    • Related Report
      2014 Research-status Report
  • [Presentation] ACE遺伝子多型は日本人柔道選手の形態および体力に影響しない2014

    • Author(s)
      上水研一朗, 位高駿夫, 有賀誠司, 町田修一
    • Organizer
      日本武道学会第47回大会
    • Place of Presentation
      福山市立大学(広島県・福山市)
    • Year and Date
      2014-09-11
    • Related Report
      2014 Research-status Report
  • [Presentation] Polymorphism of the IGF-2 gene specifies competitive capacity of Japanese judo players2013

    • Author(s)
      Itaka T, Hirokawa S, Agemizu K, Aruga S, Machida S
    • Organizer
      18th annual Congress of the European College of Sports Science
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2013 Research-status Report
  • [Presentation] 柔道選手におけるACTN3遺伝子多型についての研究-T大学柔道部を対象として-2013

    • Author(s)
      上水研一朗, 位高駿夫, 廣川彰信, 有賀誠司, 町田修一
    • Organizer
      日本武道学会第46回大会
    • Place of Presentation
      茨城県筑波大学筑波大キャンパス
    • Related Report
      2013 Research-status Report
  • [Presentation] 柔道の競技レベルを規定するアスリート遺伝子の探索-ACEとACTN3を組み合わせた検討-2013

    • Author(s)
      位高駿夫, 廣川彰信, 上水研一朗, 有賀誠司, 町田修一
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 柔道選手におけるACE遺伝子多型と全身持久力の関連性について2013

    • Author(s)
      廣川彰信, 位高駿夫, 上水研一朗, 有賀誠司, 宮崎誠司, 町田修一
    • Organizer
      第24回日本臨床スポーツ医学会学術集会
    • Place of Presentation
      熊本
    • Related Report
      2013 Research-status Report
  • [Presentation] Association of the ACTN3 and ACE Polymorphism in Japanese judo athletes

    • Author(s)
      Agemizu K, Hirokawa S, Itaka T, Aruga S, Machida S
    • Organizer
      The VIII International Judo Research Symposium
    • Place of Presentation
      Rio de Janeiro, Brazil
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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