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Physiological study regarding sleep patterns and brain function of medical residents

Research Project

Project/Area Number 25350851
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionJichi Medical University

Principal Investigator

Nishida Masaki  自治医科大学, 医学部, 講師 (10424029)

Co-Investigator(Kenkyū-buntansha) SUDA Shiro  自治医科大学, 精神医学教室, 主任教授 (40432207)
KIKUCHI Senichiro  群馬大学, 大学院保健学研究科リハビリテーション講座, 教授 (60323341)
KATO Satoshi  自治医科大学, 精神医学教室, 名誉教授 (30194814)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords疲労 / 睡眠 / 手続き記憶 / 光トポグラフィ / 活動量計 / 前頭前皮質 / 背側前頭前皮質 / 認知機能 / 認知遂行機能 / 労働環境 / 医療従事者 / 生理学 / 脳機能画像
Outline of Final Research Achievements

This study aimed to evaluate cerebral deterioration of sleep-deprived, fatigued residents using neuroimaging techniques.Six medical residents were instructed to draw blood from imitation vessels installed in the arm of a normal cooperator. They drew blood at similar times of day, before and after night duty. While they drew blood, the change in cerebral hemodynamics was measured using a wearable near-infrared spectroscopy (NIRS). Although the total sleep time and sleep efficiency did not show significant decreases, there was a significant increase in heart rate when participants drew blood after night duty. Cerebral hemodynamics represented as [oxy-Hb] and [deoxy-Hb] did not show significant differences in impairment between the pre- and post-night duty shifts; however, significant cerebral hemodynamics were significantly impaired while they drew blood after night duty. This result implies that the brains of sleep-deprived medical residents were impaired after night duty.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (16 results)

All 2015 2014 2013 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (9 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results) Book (2 results)

  • [Journal Article] Unilateral hippocampal infarction associated with an attempted suicide: a case report2014

    • Author(s)
      Nishiyori Y, Nishida M, Shioda K, Suda S Kato S.
    • Journal Title

      J Med Case Rep.

      Volume: 23 Pages: 219-219

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Topographical distribution of fast and slow sleep spindles in medicated depressive patients2014

    • Author(s)
      Nishida M, Nakashima Y, Nishikawa T.
    • Journal Title

      J Clin Neurophysiol.

      Volume: 31 Pages: 402-408

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Relation between parametric change of the workload and prefrontal cortex activity during a modified version of the 'rock, paper, scissors' task.2013

    • Author(s)
      Yamauchi Y, Kikuchi S, Miwakeichi F, Matsumoto K, Nishida M, Ishiguro M, Watanabe E, Kato S.
    • Journal Title

      Neuropsychobiology

      Volume: 68(1) Issue: 1 Pages: 24-33

    • DOI

      10.1159/000350948

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] rTMS治療前後にNIRS検査を施行した3症例2013

    • Author(s)
      齋藤陽道, 菊地千一郎, 西多昌規, 松本健二, 小林亮子, 山内芳樹, 西嶋康一, 加藤敏
    • Journal Title

      精神医学

      Volume: 55 Pages: 637-644

    • NAID

      40019709193

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] WADA規程改訂に伴うドーピング禁止物質の治療目的使用の変化2013

    • Author(s)
      鈴木智弓, 赤間高雄, 奥脇透, 川原貴, 河野一郎, 土肥美智子, 西多昌規, 山澤文裕, 渡部厚一, 和田野安良, 鈴木秀典
    • Journal Title

      日本臨床スポーツ医学会誌

      Volume: 21

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 当直後における医師の脳血流変化は低下している2015

    • Author(s)
      西多昌規 菊地千一郎 三分一史和 加藤敏
    • Organizer
      日本睡眠学会
    • Place of Presentation
      宇都宮
    • Year and Date
      2015-07-02 – 2015-07-03
    • Related Report
      2014 Research-status Report
  • [Presentation] 当直後における医師の脳血液量変化は低下しているウェアラブル光トポグラフィを用いた研究2015

    • Author(s)
      西多昌規, 菊地千一郎, 三分一史和, 田村義保, 加藤敏
    • Organizer
      第40回日本睡眠学会定期学術集会
    • Place of Presentation
      栃木県立文化センター
    • Year and Date
      2015-07-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] Impaired cerebral hemodynamics of medical residents after night duty: A wearable near-infrared spectroscopy study2015

    • Author(s)
      Masaki Nishida, Senichiro Kikuchi, Miwakeichi Fumikazu, Satoshi Kato
    • Organizer
      SLEEP 2015
    • Place of Presentation
      Washington State Convention Center
    • Year and Date
      2015-06-07
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 当直後における研修医の脳血流変化は低下している2015

    • Author(s)
      西多昌規 菊地千一郎 三分一史和 加藤敏
    • Organizer
      日本産業衛生学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-05-13 – 2015-05-15
    • Related Report
      2014 Research-status Report
  • [Presentation] 当直後における研修医の脳血液量変化は低下している2015

    • Author(s)
      西多昌規, 菊地千一郎, 三分一史和, 田村義保, 加藤敏
    • Organizer
      第88回日本産業衛生学会
    • Place of Presentation
      グランフロント大阪
    • Year and Date
      2015-05-13
    • Related Report
      2015 Annual Research Report
  • [Presentation] うつ病性障害の反復経頭蓋磁気刺激治療における行動量、睡眠状態の変化について

    • Author(s)
      西多昌規, 菊地千一郎, 齋藤陽道, 松本健二, 山内芳樹, 須田史朗, 塩田勝利, 西嶋康一, 加藤敏
    • Organizer
      第109回日本精神神経学会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] うつ病性障害の反復経磁気刺激治療における治療効果と睡眠指標との関連性

    • Author(s)
      西多昌規, 斎藤陽道, 菊地千一郎, 松本健二, 塩田勝利, 須田史朗, 西嶋康一, 加藤敏
    • Organizer
      第38回日本睡眠学会定期学術集会
    • Place of Presentation
      秋田
    • Related Report
      2013 Research-status Report
  • [Presentation] 散歩療法が奏功した回復期うつ病の3症例

    • Author(s)
      西多昌規, 福田和仁, 須田史朗, 加藤敏
    • Organizer
      第11回日本スポーツ精神医学会学会総会・学術集会
    • Place of Presentation
      犬山
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 睡眠覚醒リズム評価を用いたうつ病の病態解明と治療

    • Author(s)
      西多昌規
    • Organizer
      第43回 日本臨床神経生理学会学術大会
    • Place of Presentation
      高知
    • Related Report
      2013 Research-status Report
    • Invited
  • [Book] 隠れている軽い統合失調症を発見するには.2013

    • Author(s)
      西多昌規(共著)
    • Publisher
      羊十社
    • Related Report
      2013 Research-status Report
  • [Book] 睡眠とその障害のクリニカルクエスチョン2002013

    • Author(s)
      西多昌規(共著)
    • Publisher
      診断と治療社
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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