| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Outline of Final Research Achievements |
DNA-immobilized Fe3O4 particles (DNA-Fe-particles) were prepared by mixing DNA, magnetic Fe3O4 particles, and the silane coupling reagent. These DNA-Fe-particles were stable in water. Additionally, we could simply collect the DNA-Fe-particles by a magnet from an aqueous solution. In addition, we demonstrated the accumulation of various metal ions, such as heavy and rare-earth metal ions, by the DNA-Fe-particles. As a result, although these DNA-Fe-particles could selectively accumulate heavy and rare-earth metal ions, these materials could not accumulate the light metal ions, such as Mg(II) and Ca(II) ions. Furthermore, the metal ion-accumulated DNA-Fe-particles could be recycled by washing them with an aqueous EDTA solution. Therefore, the DNA-Fe-particles may have potential use for biomedical application, such as the removal of harmful heavy metal ion in human body, and environmental applications, such as the accumulation of rare-earth metals from industrial waste.
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