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cortical local circuit with network motifs and cluster structure

Research Project

Project/Area Number 25430028
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurophysiology / General neuroscience
Research InstitutionOsaka University

Principal Investigator

Teramae Jun-nosuke  大阪大学, 情報科学研究科, 准教授 (50384722)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords大脳皮質 / ゆらぎ / ノイズ / 確率 / ネットワークモチーフ / スモールワールド / 脳 / 抑制性神経細胞 / 複雑ネットワーク / クラスター / 同期 / 受容野 / 局所回路 / 確率的推定 / 神経 / 不均一性 / 抑制 / フィードバック / ネットワーク / クラスタ構造
Outline of Final Research Achievements

Cortical networks sustain asynchronous irregular firing with low firing rate. Recent theoretical studies have revealed that coexistence of many weak and a few extremely strong excitatory synapses, plays an essential role in realizing the self-sustained activity. However, highly nonrandom features of the synaptic connectivity, i.e. cluster structure or bidirectional connections between cortical neurons have not been considered. The positive correlation of synaptic connections destabilize asynchronous activity Here, we show that the synchronization can be efficiently suppressed by highly heterogeneous distribution, typically a lognormal distribution, of inhibitory-to-excitatory connection in a recurrent network model of cortical neurons. We also found that clusters are not isolated in cortical network independently. Rather, they connected each other and globally they form so-called a small world network in local cortical network.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (37 results)

All 2015 2014 Other

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Open Access: 2 results,  Acknowledgement Compliant: 4 results) Presentation (31 results) (of which Int'l Joint Research: 2 results,  Invited: 19 results) Remarks (1 results)

  • [Journal Article] Synchronized Firing Induced by Correlated Bidirectional Couplings in a Neural Network Model for Spontaneous Activity2015

    • Author(s)
      Hisashi Kada, Jun-Nosuke Teramae, and Isao T. Tokuda
    • Journal Title

      Journal of Signal Processing

      Volume: 19 Pages: 107-110

    • NAID

      130005090470

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Brain-inspired communication technologies: Information networks with continuing internal dynamics and fluctuation2015

    • Author(s)
      J. Teramae, N. Wakamiya
    • Journal Title

      IEICE Trans. Commun

      Volume: E98 Pages: 153-159

    • NAID

      130004841603

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Computational Implications of Lognormally Distributed Synaptic Weights2014

    • Author(s)
      Jun-nosuke Teramae, Tomoki Fukai
    • Journal Title

      Proceedings of the IEEE

      Volume: 102 Issue: 4 Pages: 500-512

    • DOI

      10.1109/jproc.2014.2306254

    • Related Report
      2013 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Lessons from spontaneous neural noise genesis on neuromorphic engineering2014

    • Author(s)
      Tomoki Fukai, Jun-nosuke Teramae
    • Journal Title

      Proceedings of the IEEE

      Volume: 102 Issue: 4 Pages: 513-513

    • DOI

      10.1109/jproc.2014.2307019

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dense neuron clustering explains connectivity statistics in cortical microcircuits2014

    • Author(s)
      Vladimir V Klinshov, Jun-nosuke Teramae, Vladimir I Nekorkin, Tomoki Fukai
    • Journal Title

      PLoS One

      Volume: 9 Issue: 4 Pages: 1-12

    • DOI

      10.1371/journal.pone.0094292

    • Related Report
      2013 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Fluctuation in the brain and a possible application to ICT2015

    • Author(s)
      Jun-nosuke Teramae, Naoki Wakamiya
    • Organizer
      The Second International Workshop on Brain-Inspired Information Communication Technologies
    • Place of Presentation
      Columbia University (NY, USA)
    • Year and Date
      2015-12-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 脳と学習の情報理論2015

    • Author(s)
      寺前順之介
    • Organizer
      数理モデリング研究会
    • Place of Presentation
      大津(滋賀)
    • Year and Date
      2015-11-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] 中枢神経系のネットワーク特性と情報処理2015

    • Author(s)
      寺前順之介
    • Organizer
      国際高等研究所ネットワークの科学研究会
    • Place of Presentation
      熱海(静岡)
    • Year and Date
      2015-10-01
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 揺らぎと非線形性による大脳皮質の確率的情報処理と学習則2015

    • Author(s)
      寺前順之介
    • Organizer
      ランダム力学系理論とその応用
    • Place of Presentation
      数理解析研究所(京都)
    • Year and Date
      2015-09-30
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Origin and functional roles of ongoing fluctuation in the brain2015

    • Author(s)
      寺前順之介
    • Organizer
      22世紀創造のための数学
    • Place of Presentation
      アキバホール(東京)
    • Year and Date
      2015-09-29
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Long-tailed distribution of synaptic strength reveals origin and functional roles of ongoing fluctuation in cortical circuit2015

    • Author(s)
      Jun-nosuke Teramae
    • Organizer
      13TH INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS (ICNAAM 2015)
    • Place of Presentation
      Rhodes (Greece)
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 大脳皮質自発揺らぎの回路構造と非線形ダイナミクス2015

    • Author(s)
      寺前順之介
    • Organizer
      第28回回路とシステムワークショップ
    • Place of Presentation
      淡路島(兵庫)
    • Year and Date
      2015-08-04
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 大脳皮質局所回路の結合不均一性と自発発火活動2015

    • Author(s)
      寺前順之介
    • Organizer
      脳のセミナー
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2015-04-19
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 神経システムにおける「むだ」と「あそび」:疎構造の多重性2015

    • Author(s)
      寺前順之介
    • Organizer
      日本物理学会第70回年次大会
    • Place of Presentation
      早稲田大学(東京・新宿)
    • Year and Date
      2015-03-22
    • Related Report
      2014 Research-status Report
  • [Presentation] 抑制性結合の不均一性による神経発火活動の脱同期と安定化2015

    • Author(s)
      嘉田久嗣,寺前順之介,徳田功
    • Organizer
      日本物理学会第70回年次大会
    • Place of Presentation
      早稲田大学(東京・新宿)
    • Year and Date
      2015-03-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 神経細胞モデル集団の周波数応答2015

    • Author(s)
      梅原広明,寺前順之介,成瀬康
    • Organizer
      日本物理学会第70回年次大会
    • Place of Presentation
      早稲田大学(東京・新宿)
    • Year and Date
      2015-03-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 発火ニューロンモデルから組むニューラルマス要素モデル2015

    • Author(s)
      梅原広明,寺前順之介,成瀬康
    • Organizer
      電子情報通信学会ニューロコンピューティング研究会
    • Place of Presentation
      玉川大学(東京・町田)
    • Year and Date
      2015-03-17
    • Related Report
      2014 Research-status Report
  • [Presentation] 複雑コミュニケーションサイエンスに向けた理論研究からのアプローチ2015

    • Author(s)
      寺前順之介
    • Organizer
      電子情報通信学会総合大会,複雑コミュニケーションサイエンス
    • Place of Presentation
      立命館大学(滋賀・草津)
    • Year and Date
      2015-03-11
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Stability of Asynchronous Firing Induced by Lognormally Distributed Inhibitory Connection2015

    • Author(s)
      Hisashi Kada, Jun-nosuke Teramae, Isao T. Tokuda
    • Organizer
      RISP International Workshop on Nonlinear Circuits, Communications and Signal Processing (NCSP'15)
    • Place of Presentation
      Kuala Lumpur (Malaysia)
    • Year and Date
      2015-03-01
    • Related Report
      2014 Research-status Report
  • [Presentation] Liquid State Machine with Heterogeneous Connections for Information Networks2014

    • Author(s)
      Kaku Yamaguchi, Jun-nosuke Teramae, Naoki Wakamiya
    • Organizer
      International Symposium on Nonlinear Theory and its Applications (NOLTA 2014)
    • Place of Presentation
      Luzern (Switzerland)
    • Year and Date
      2014-09-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Intrinsic fluctuation in the cortical network and its application for neural computation2014

    • Author(s)
      Jun-nosuke Teramae
    • Organizer
      International Symposium on Nonlinear Theory and its Applications (NOLTA 2014)
    • Place of Presentation
      Luzern (Switzerland)
    • Year and Date
      2014-09-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Origin and computational roles of intrinsic heterogeneity and spontaneous fluctuation in cortical networks2014

    • Author(s)
      Jun-nosuke Teramae
    • Organizer
      AIMS Conference on Dynamical Systems, Differential Equations and Applications
    • Place of Presentation
      Madrid (Spain)
    • Year and Date
      2014-07-08
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 大脳皮質の自発発火モデルにおける抑制性神経回路の役割2014

    • Author(s)
      嘉田久嗣,寺前順之介,徳田功
    • Organizer
      第10回電子情報通信学会複雑コミュニケーションサイエンス時限研究会
    • Place of Presentation
      大阪大学(大阪・吹田)
    • Year and Date
      2014-05-15
    • Related Report
      2014 Research-status Report
  • [Presentation] Optimal Spike-Based Communication with Internal Fluctuation in Cortical Networks

    • Author(s)
      Jun-nosuke Teramae
    • Organizer
      International Symposium on Nonlinear Theory and its Applications
    • Place of Presentation
      Santa Fe, USA
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Origin and functional roles of spontaneous noise in the brain: Self-organized stochastic resonance and memory states

    • Author(s)
      Jun-nosuke Teramae
    • Organizer
      Modeling Neural Activity: Statistics, Dynamical Systems, and Networks
    • Place of Presentation
      Lihue, USA
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Noise-Induced Order and Computation in the Brain

    • Author(s)
      Jun-nosuke Teramae
    • Organizer
      Progress of Mathematical Studies in Neuroscience
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 脳情報通信におけるゆらぎの機能的役割

    • Author(s)
      寺前 順之介
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      新潟大学
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 大脳皮質局所回路網におけるゆらぎと確率性の理論研究

    • Author(s)
      寺前 順之介
    • Organizer
      視覚科学統合研究センターシンポジウム 「視覚情報処理の新展開-局所回路から認知へ」
    • Place of Presentation
      立命館大学
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 大脳皮質における揺らぎの起源と神経情報処理における機能

    • Author(s)
      寺前 順之介
    • Organizer
      日本学術振興会 分子系の複合電子機能第181委員会
    • Place of Presentation
      国際高等研究所
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 神経活動と大規模システムにおける揺らぎの意義

    • Author(s)
      寺前 順之介
    • Organizer
      ランダム力学系理論とその応用
    • Place of Presentation
      京都大学数理解析研究所
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 大脳皮質における自発揺らぎの理論的解明

    • Author(s)
      寺前 順之介
    • Organizer
      視覚科学の統合的研究センターセミナー
    • Place of Presentation
      立命館大学
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 神経情報処理における自発揺らぎの起源と機能

    • Author(s)
      寺前 順之介
    • Organizer
      日本時間生物学会シンポジウム「生物リズム現象の数理フロンティア」
    • Place of Presentation
      近畿大学
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 揺らぎをつくり活かす大脳皮質の情報処理メカニズム

    • Author(s)
      寺前 順之介
    • Organizer
      高等研究所「脳をシステムとして理解する-神経回路の動作原理と機能創発-」
    • Place of Presentation
      早稲田大学
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 脳皮質自発発火活動と確率的記憶状態

    • Author(s)
      寺前 順之介, 坪 泰宏, 平谷 直輝, 深井 朋樹
    • Organizer
      第36回日本神経科学会
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 大規模システムとしての大脳皮質ゆらぎの効果

    • Author(s)
      寺前順之介
    • Organizer
      日本物理学会第69回年次大会
    • Place of Presentation
      東海大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 大脳皮質の自発発火モデルにみられる同期現象の抑制性神経回路による制御

    • Author(s)
      嘉田久嗣,寺前順之介,徳田功
    • Organizer
      日本物理学会第69回年次大会
    • Place of Presentation
      東海大学
    • Related Report
      2013 Research-status Report
  • [Remarks] Jun-nosuke Teramaeのホームページ

    • URL

      http://www-waka.ics.es.osaka-u.ac.jp/~teramae/index.html

    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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