| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
The hepatic architecture of vertebrates was classified into two types; portal triad-type with intrahepatic bile ducts running along portal veins, and non-portal triad-type with intrahepatic bile ducts independent of portal veins. The latter was observed in many actinopterygians, and the former was seen in other vertebrates, including agnathans, chondrichthyans and mammals. In a process of diversification of actinopterygians, the portal triad-type hepatic architecture gradually changed into the non-portal triad-type hepatic architecture. Fishes of Elopiformes had an intermediate hepatic architecture of both types. Amino acid sequences of Jag1, which is responsible for biliary induction in mammals, were comparatively analyzed among vertebrates with special attention paid to the hepatic architectures.
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