| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
The search for new anti-trypanosomal natural products from marine organisms was performed. As a result, seventeen new natural products were isolated from marine sponges and dinoflagellates, and the structures of new compounds were elucidated. Three new compounds were analogs of anti-trypanosomal natural products previously found by us. These compounds were isolated to analyze the structure activity relationships of anti-trypanosomal natural products. The detailed investigation about anti-trypanosomal activity of new compounds were currently in progress.
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