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Degrading anticancer drugs in the medical environment using a photocatalyst

Research Project

Project/Area Number 25460219
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical pharmacy
Research InstitutionIwate Medical University

Principal Investigator

KUDO Kenzo  岩手医科大学, 薬学部, 教授 (30275531)

Co-Investigator(Renkei-kenkyūsha) SATO Junya  岩手医科大学, 薬学部, 講師 (40616413)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords抗がん剤分解 / 抗がん剤被曝低減 / 光触媒 / 可視光応答型光触媒 / 紫外線応答型光触媒 / 抗がん剤 / 医療被曝 / 分解 / 可視光反応型光触媒 / 被曝 / 被爆
Outline of Final Research Achievements

Occupational exposure to anticancer drugs is recognized as a risk for healthcare workers. Reducing anticancer drugs in the environment is important to prevent the exposure of individuals to anticancer drugs. However, there are currently no effective degrading agents for all anticancer drugs used in clinical settings. In this study, we evaluated anticancer drug degradation using a photocatalyst. The visible light-driven photocatalyst as a spray agent was confirmed to degrade anticancer drugs under a fluorescent lamp. The ultraviolet-driven photocatalyst as a coating agent degraded anticancer drugs. Degradation of anticancer drugs by the visible light-driven photocatalyst as a coating agent is lesser than the ultraviolet-driven photocatalyst as a coating agent. The ability of photocatalyst is useful tool for reducing anticancer drug pollution in clinical settings.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (6 results)

All 2016 2015 2014

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 2 results) Presentation (3 results)

  • [Journal Article] 医療環境中に汚染された抗がん剤を可視光応答型光触媒にて分解する試み2014

    • Author(s)
      佐藤淳也、菊地聡美、工藤賢三
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 134 Pages: 909-914

    • NAID

      130004677650

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 抗がん剤調製時に使用する作業シートの吸着性評価2014

    • Author(s)
      佐藤淳也、菊地聡美、工藤賢三
    • Journal Title

      日本病院薬剤師会雑誌

      Volume: 50 Pages: 1040-1043

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 抗がん剤調製環境における汚染調査 ~クーポン法による5-FUモニタリングの有用性~2014

    • Author(s)
      佐藤淳也、森恵、佐々木拓也、二瓶哲、熊谷真澄、中山誠也、高橋勝雄、工藤賢三
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 134 Pages: 751-756

    • NAID

      130004427990

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] 抗がん剤汚染の低減を目的とした新規作業シートの開発と汚染低減メカニズムの検討2016

    • Author(s)
      古川美咲、佐藤淳也、吉田翔、工藤賢三
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 抗がん剤調製下に使用する新規作業シートの開発2015

    • Author(s)
      佐藤淳也、吉田翔、古川美咲、堀田靖則、工藤賢三
    • Organizer
      第25回日本医療薬学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2015-11-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] 可視光反応型光触媒を利用した抗癌剤分解の検討2014

    • Author(s)
      菊地聡美、佐藤淳也、工藤賢三
    • Organizer
      第134回日本薬学会年会
    • Place of Presentation
      熊本市
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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