Evaluation of change at the time of passing thyroid ultrasound findings in general children

• Project/Area Number: 25460760
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Nagasaki University
• Principal Investigator: HAYASHIDA Naomi 長崎大学, 原爆後障害医療研究所, 教授 (00420638)
• Co-Investigator(Kenkyū-buntansha): 高村 昇 長崎大学, 原爆後障害医療研究所, 教授 (30295068) ; 鈴木 眞一 福島県立医科大学, 医学部, 教授 (70235951) ; 南 恵樹 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 (90398165)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 甲状腺 / 有所見率 / のう胞 / 結節 / 小児 / 転帰 / 経時的変化

Outline of Final Research Achievements

After the accident of Fukushima Nuclear Power Plant, thyroid ultrasound examination of children is conducted in Fukushima Prefecture. In this screening, small thyroid cysts are detected in approximately half of these children. On the other hand, there are few report about the prevalence of thyroid nodules or cysts in Japanese children. In this study, we conduct thyroid ultrasound examination in Japanese residents.
As the results, small thyroid cysts are detected in approximately half and small thyroid nodules are detected in 0.7% of the subjects. Each prevalence was same as that of Fukushima. The prevalence of nodules detected in adults was higher than children. The finding or thyroid cysts in children was changed during our four years follow up survey.

Research Products

• [Journal Article] Association between circulating CD34-positive cells and serum alkaline phosphatase in relation to body mass index for elderly Japanese men. (2016)
  • Author(s): Yuji Shimizu, Shimpei Sato, Jun Koyamatsu, Hirotomo Yamanashi, Mako Nagayoshi, Koichiro Kadota, Kazuto Tsuruda, Naomi Hayashida, Norio Abiru, Hironori Yamasaki, Noboru Takamura and Takahiro Maeda.
  • Journal Title: Journal of Physiological Anthropology Volume: 35 Issue: 1 Pages: 2-2
  • DOI: 10.1186/s40101-016-0084-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Radiocesium concentrations in wild mushrooms collected in Kawauchi Village after the accident at the Fukushima Daiichi Nuclear Power Plant (2015)
  • Author(s): Nakashima K, Orita M, Fukuda N, Taira Y, Hayashida N, Matsuda N, Takamura N
  • Journal Title: PeerJ Volume: 3 Pages: e1427-e1427
  • DOI: 10.7717/peerj.1427
  • NAID: 120006986806
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Increase in Operator’s Sympathetic Nerve Activity during Complicated Hepatobiliary Surgery: Evidence for Surgeons’ Mental Stress (2015)
  • Author(s): Kosho Yamanouchi, Naomi Hayashida, Sayaka Kuba, Chika Sakimura, Tamotsu Kuroki, Michita Togo, Noritada Katayama, Noboru Takamura, Susumu Eguchi.
  • Journal Title: The Tohoku Journal of Experimental Medicine Volume: 237 Issue: 3 Pages: 157-162
  • DOI: 10.1620/tjem.237.157
  • NAID: 130005102857
  • ISSN: 0040-8727, 1349-3329
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of the Relationship between Current Internal 137Cs Exposure in Residents and Soil (2015)
  • Author(s): Kimura Y, Okubo Y, Hayashida N, Takahashi J, Gutevich A, Chorniy S, Kudo T, Takamura N
  • Journal Title: PLoS One Volume: 10 Issue: 9 Pages: e0139007-e0139007
  • DOI: 10.1371/journal.pone.0139007
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Changes in radiological imaging frequencies in children before and after the accident at the Fukushima Daiichi Nuclear Power Plant in Fukushima Prefecture, Japan (2015)
  • Author(s): Yoshida K, Hayashida N, Fukushima Y, Ohtsuru A, Ohba T, Hasegawa A, Sato H, Shishido F, Yasui K, Kumagai A, Yusa T, Kudo T, Yamashita S, Takamura N.
  • Journal Title: Japanese Journal of Radiology Volume: 33 Issue: 10 Pages: 619-26
  • DOI: 10.1007/s11604-015-0464-8
  • NAID: 50009607231
  • Peer Reviewed / Open Access
• [Journal Article] Bipolarization of Risk Perception about the Health Effects of Radiation in Residents after the Accident at Fukushima Nuclear Power Plant. (2015)
  • Author(s): Orita M, Hayashida N, Nakayama Y, Shinkawa T, Urata H, Fukushima Y, Endo Y, Yamashita S, Takamura N
  • Journal Title: PLoS One Volume: 10 Issue: 6 Pages: e0129227-e0129227
  • DOI: 10.1371/journal.pone.0129227
  • NAID: 120006987000
  • Peer Reviewed / Open Access
• [Journal Article] Thyroid ultrasound findings in a follow-up survey of children from three Japanese prefectures: Aomori, Yamanashi, and Nagasaki (2015)
  • Author(s): Naomi Hayashida, Misa Imaizumi, Hiroki Shimura, Fumihiko Furuya, Noriyuki Okubo, Yasushi Asari, Takeshi Nigawara, Sanae Midorikawa, Kazuhiko Kotani, Shigeyuki Nakaji, Akira Ohtsuru, Takashi Akamizu, Masafumi Kitaoka, Shinichi Suzuki, Nobuyuki Taniguchi, Shunichi Yamashita & Noboru Takamura
  • Journal Title: SCIENTIFIC REPORTS Volume: 5 Issue: 1 Pages: 9046-9046
  • DOI: 10.1038/srep09046
  • NAID: 120006987130
  • Peer Reviewed / Open Access
• [Journal Article] Factors Associated with Nurses’ Intention to Leave Their Jobs after the Fukushima Daiichi Nuclear Power Plant Accident. (2015)
  • Author(s): Sato Y, Hayashida N, Orita M, Urata H, Shinkawa T, Fukushima Y, Nakashima Y, Kudo T, Yamashita S, Takamura N
  • Journal Title: PLoS One Volume: 10(3) Issue: 3 Pages: e0122389-e0122389
  • DOI: 10.1371/journal.pone.0122389
  • NAID: 120006987055
  • Peer Reviewed / Open Access
• [Journal Article] Measurement of Individual Doses of Radiation by Personal Dosimeter is Important for the Return of Residents from Evacuation Order Areas after Nuclear Disaster. (2015)
  • Author(s): Orita M, Hayashida N, Taira Y, Fukushima Y, Ide J, Endo Y, Kudo T, Yamashita S, Takamura N
  • Journal Title: PLoS One Volume: 10(3) Issue: 3 Pages: e0121990-e0121990
  • DOI: 10.1371/journal.pone.0121990
  • Peer Reviewed / Open Access
• [Journal Article] The A>T Polymorphism of the Tribbles Homolog 1 Gene Is Associated with Serum Triglyceride Concentrations in Japanese Community-Dwelling Women (2014)
  • Author(s): Ikeoka T, Hayashida N, Nakazato M, SekitaH, Murata-Mori F, Ando T, Abiru N, Yamasaki H, Kudo T, Maeda T, Kawakami A, Takamura N.
  • Journal Title: The Tohoku Journal of Experimental Medicine Volume: 233 Issue: 2 Pages: 149-153
  • DOI: 10.1620/tjem.233.149
  • NAID: 130004822418
  • ISSN: 0040-8727, 1349-3329
  • Peer Reviewed / Open Access
• [Journal Article] Uptake of aortic 18F-FDG is correlated with low-density lipoprotein cholesterol and leptin in a general population. (2014)
  • Author(s): Haraguchi A, Hayashida N, Kamasaki T, Miyamoto I, Usui T, Ando T, Abiru N, Yamasaki H, Chiba K, Kudo T, Kawakami A, Takamura N.
  • Journal Title: PLoS ONE Volume: 9
  • NAID: 120006986351
  • Peer Reviewed / Open Access
• [Journal Article] Internal radiation exposure dose in Iwaki City, Fukushima Prefecture after the accident at Fukushima Dai-ichi Nuclear Power Plant. (2014)
  • Author(s): Orita M, Hayashida N, Nukui H, Fukuda N, Kudo T, Matsuda N, Fukushima Y, Takamura N
  • Journal Title: PloS One Volume: 9(12) Issue: 12 Pages: e114407-e114407
  • DOI: 10.1371/journal.pone.0114407
  • NAID: 120006986312
  • Peer Reviewed / Open Access
• [Journal Article] Timing of drainage tube removal after thyroid surgery: a retrospective study. (2014)
  • Author(s): Minami S, Sakimura C, Hayashida N, Yamanouchi K, Kuroki T, Eguchi S.
  • Journal Title: Surgery today Volume: 44 Issue: 1 Pages: 137-141
  • DOI: 10.1007/s00595-013-0531-7
  • Peer Reviewed
• [Journal Article] PET/CT shows subjective pain in shoulder joints to be associated with uptake of (18)F-FDG. (2014)
  • Author(s): Kamasaki T, Hayashida N, Miyamoto I, Usui T, Chiba K, Kudo T, Takamura N.
  • Journal Title: Nuclear medicine communications Volume: 35 Issue: 1 Pages: 44-50
  • DOI: 10.1097/mnm.0000000000000029
  • NAID: 120006985998
  • Peer Reviewed
• [Journal Article] Evaluation of the effectiveness of warm footbath on heart rate variability in patients with profound multiple disabilities. (2014)
  • Author(s): Orita M, Hayashida N, Shinkawa T, Urata T, Kudo T, Koga M, Katayama S, Togo M, Hiramatsu K, Takamura N.
  • Journal Title: Life Science Journal Volume: 11 Pages: 88-92
  • Peer Reviewed
• [Journal Article] Clinical usefulness of 18F-FDG PET/CT for the screening of metabolic disorders. (2014)
  • Author(s): Irie S, Hayashida N, Shinkawa T, Kamasaki T, Matsunaga A, Miyamoto I, Usui T, Chiba K, Kudo T, Takamura N.
  • Journal Title: Life Science Journal Volume: 11 Pages: 99-104
  • Peer Reviewed
• [Journal Article] Urinary iodine concentrations of pregnant women in Ukraine. (2013)
  • Author(s): Sekitani Y, Hayashida N, Takahashi J, Kozlovsky AA, Rudnitskiy S, Petrova A, Gutevych OK, Chorniy SA, Yamashita S, Takamura N
  • Journal Title: Clim Chem Lab Med Volume: 51巻 Issue: 4 Pages: 811-816
  • DOI: 10.1515/cclm-2012-0397
  • NAID: 120006986785
  • Peer Reviewed
• [Journal Article] Determinants of homocysteine concentrations in mother and neonatal girl pairs (2013)
  • Author(s): Y. Sekitani, N. Hayashida, T. Ikeoka, A. Yoshida, M. Nakazato, M. Wada, A. Fujita, A. Matsuo, T. Miyamura, M. Obama, K. Nakashima, T. Maeda, H. Masuzaki, N. Takamura
  • Journal Title: Clin. Chem. Lab. Med Volume: 3 Issue: 5 Pages: 1-4
  • DOI: 10.1515/cclm-2012-0685
  • NAID: 120006986115
  • Peer Reviewed
• [Journal Article] Ultrasonographic thyroid nodular findings in Japanese children. (2013)
  • Author(s): Taniguchi N, Hayashida N, Shimura H, Okubo N, Asari Y, Nigawara T, Midorikawa S, Kotani K, Nakaji S, Imaizumi M, Ohtsuru A, Akamizu T, Kitaoka M, Suzuki S, Yamashita S, Takamura N
  • Journal Title: J Med Ultrasonics Volume: 40巻 Issue: 3 Pages: 219-224
  • DOI: 10.1007/s10396-013-0456-1
  • Peer Reviewed
• [Journal Article] Carcinomas in the remnant thyroid after thyroidectomy for Graves’ disease: report of a case. (2013)
  • Author(s): Yamanouchi K, Minami S, Hayashida N, Sakimura C, Hayashi T, Kinoshita N, Ueki I, Kuroki T, Eguchi S.
  • Journal Title: Acta medica Nagasakiensia Volume: 58 Pages: 63-66
  • NAID: 110009614188
  • Peer Reviewed
• [Journal Article] Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer. (2013)
  • Author(s): Akilzhanova A, Nurkina Z, Momynaliev K, Ramanculov E, Zhumadilov Z, Rakhypbekov T, Hayashida N, Nakashima M, Takamura N.
  • Journal Title: Anticancer Research Volume: 33 Pages: 4049-4059
  • Peer Reviewed
• [Journal Article] Determinants of the return to hometowns after the accident at Fukushima Dai－Ichi Nuclear Power Plant： a case study for the village of Kawauchi. (2013)
  • Author(s): Orita M, Hayashida N, Urata H, Shinkawa T, Endo Y, Takamura N.
  • Journal Title: Radiation protection dosimetry Volume: 156 Issue: 3 Pages: 383-385
  • DOI: 10.1093/rpd/nct082
  • NAID: 120006986799
  • Peer Reviewed
• [Journal Article] Can the use of intraoperative intact parathyroid hormone monitoring be abandoned in patients with hyperparathyroidism? (2013)
  • Author(s): Sakimura C, Minami S, Hayashida N, Uga T, Inokuchi N, Eguchi S.
  • Journal Title: American journal of surgery Volume: 206 Issue: 4 Pages: 574-577
  • DOI: 10.1016/j.amjsurg.2013.01.043
  • NAID: 120006986053
  • Peer Reviewed
• [Journal Article] Thyroid ultrasound findings in children from three Japanese prefectures: Aomori, Yamanashi and Nagasaki. (2013)
  • Author(s): Hayashida N, Imaizumi M, Shimura H, Okubo N, Asari Y, Nigawara T, Midorikawa S, Kotani K, Nakaji S, Ohtsuru A, Akamizu T, Kitaoka M, Suzuki S, Taniguchi N, Yamashita S, Takamura S
  • Journal Title: PloS One Volume: 8巻 Issue: 12 Pages: e83220-e83220
  • DOI: 10.1371/journal.pone.0083220
  • NAID: 120006986696
  • Peer Reviewed
• [Presentation] Thyroid Ultrasound Findings in Children from Nagasaki (2017)
  • Author(s): Izumi Yamaguchi
  • Organizer: The 1st International Symposium of the network-type Joint Usage/Research Center for Radiation Disaster Medical Science
  • Place of Presentation: 広仁会館（広島県・広島市）
  • Year and Date: 2017-02-21
  • Int'l Joint Research
• [Presentation] 3県の有所見率調査の結果について (2016)
  • Author(s): 林田直美
  • Organizer: 日本超音波医学会第89回学術集会
  • Place of Presentation: 国立京都国際会館（京都府・京都市）
  • Year and Date: 2016-05-27
• [Presentation] 3県調査と過剰診断 (2015)
  • Author(s): 林田直美、今泉美彩、志村浩己、大久保礼由、浅利 靖、二川原 健、緑川早苗、小谷和彦、中路重之、大津留 晶、赤水尚史、貴田岡正史、鈴木眞一、高村 昇、山下俊一、谷口信行
  • Organizer: 第35回日本乳腺甲状腺超音波医学会
  • Place of Presentation: 岩手県民情報交流センター「アイーナ」（岩手・盛岡）
  • Year and Date: 2015-09-19
• [Presentation] 小児の甲状腺超音波検査における有所見率；３県調査の結果 (2014)
  • Author(s): 林田直美，今泉美彩，志村浩己，大久保礼由，浅利 靖，二川原健，緑川早苗，小谷和彦，中路重之，大津留晶，赤水尚史，貴田岡正史，鈴木眞一，谷口信行，山下俊一，高村 昇
  • Organizer: 第57回日本甲状腺学会学術集会
  • Place of Presentation: コングレコンベンションセンター（大阪府大阪市）
  • Year and Date: 2014-11-13 – 2014-11-15
  • Invited
• [Presentation] 3 県の有所見率調査の結果について (2014)
  • Author(s): 林田直美，今泉美彩，志村浩己，大久保礼由，浅利 靖，二川原健，緑川早苗，小谷和彦，中路重之，大津留晶，赤水尚史，貴田岡正史，鈴木眞一，谷口信行，山下俊一，高村 昇
  • Organizer: 日本超音波医学会第87回学術集会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-05-09 – 2014-05-11
  • Invited
• [Presentation] 3県の有所見率調査の結果について (2014)
  • Author(s): 林田直美，今泉美彩，志村浩己，大久保礼由，浅利 靖，二川原 健，緑川早苗，小谷和彦，中路重之，大津留 晶，赤水尚史，貴田岡正史，鈴木眞一，谷口信行，山下俊一，高村 昇
  • Organizer: 日本超音波医学会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Invited
• [Presentation] 心拍間隔変動パワースペクトル解析による甲状腺手術前後の自律神経評価 (2013)
  • Author(s): 木村悠子，林田直美，南 恵樹，山之内孝彰，東郷道太，白水重憲，片山宗哲，江口 晋，高村 昇
  • Organizer: 日本内分泌学会学術総会
  • Place of Presentation: 仙台国際センター（宮城県仙台市）
• [Presentation] ネットワークシステムを利用した離島地域での被爆者健康講話開催の取り組み (2013)
  • Author(s): 林田直美，新川哲子，岩下一也，坂口真一，智多正信，浦田秀子，高村 昇
  • Organizer: 日本放射線看護学会学術集会
  • Place of Presentation: 長崎大学良順会館（長崎県長崎市）
• [Book] インナービジョン3 (2017)
  • Author(s): 林田直美
  • Total Pages: 4
  • Publisher: インナービジョン