Improvements of the catheter treatment and gene analysis for patients with pulmonary arteriovenous malformations
Project/Area Number |
25461150
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Respiratory organ internal medicine
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Research Institution | Chiba University |
Principal Investigator |
KASAHARA YASUNORI 千葉大学, 医学(系)研究科(研究院), 特任教授 (60343092)
|
Co-Investigator(Kenkyū-buntansha) |
SUGIURA Toshihiko 千葉大学, 医学部附属病院, 助教 (20527882)
SAKAO Seiichiro 千葉大学, 医学部附属病院, 講師 (80431740)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 肺動静脈奇形 / 肺動静脈瘻 / インターベンション / コイル塞栓 / 遺伝性出血性末梢血管拡張症 / コイル / 遺伝性出血性毛細血管拡張症 |
Outline of Final Research Achievements |
Pulmonary arteriovenous fistula (pAVM) is the pulmonary vascular disease which pulmonary artery and pulmonary vein shunt without passing through the capillary. We studied the clinical features of patients of pAVM and transcatheter coil embolotherapy. We estimated the rate of shrinkage of the longest diameter of the aneurysmal sac and the presence of coil recanalization using 4D dynamic contrast-enhanced 320-slice CT. All the lesions that had disappearance of the aneurysmal sac showed successful treatment. All the lesion which had < 30% reduction in sac size, showed recanalization on CT. Residual fistula that had > 30% reduction in the size of the aneurysmal sac were observed recanalization in 60% of lesions. It is important to make the fully embolization.
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Report
(4 results)
Research Products
(7 results)
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[Presentation] PAHを初発症状としたACVRL1遺伝子変異陽性HHTの一例2014
Author(s)
石綿司,寺田二郎, 田邉信宏, 安部光洋, 杉浦寿彦, 多田裕司, 津島健司, 笠原靖紀, 巽浩一郎
Organizer
第2回日本肺高血圧症学会(JPHS)第3回日本肺循環学会(JPCS)合同学術集会
Place of Presentation
東京都 千代田区 大手町サンケイプラザ
Year and Date
2014-10-03 – 2014-10-05
Related Report
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