• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Study for risk factors and prevention of osteoporotic fractures

Research Project

Project/Area Number 25462293
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionTottori University

Principal Investigator

Hagino Hiroshi  鳥取大学, 医学部, 教授 (80208412)

Research Collaborator NAGIRA Keita  
TSUKUTANI Yasuto  
YAMASAKI Yusuke  
KOBAYASHI Eri  
MATSUDA Risa  
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords脆弱性骨折 / 骨粗鬆症 / 大腿骨近位部骨折 / リハビリテーション / 老化
Outline of Final Research Achievements

Number of patients with osteoporosis-related limb fractures has been increased and the incidence has been also increased with time in Tottori Prefecture. Less than one third in fragility fracture patients were treated by osteoporosis medication after the fracture. End stage knee osteoarthritis patients showed high fall risk and foot deformity was defined as an independent risk factor for fall. Muscle power of knee extension and gait speed correlated with fear for fall. Functional electrical stimulator was used to improve gait in healthy elderly; however, no significant change was observed. Removable stride-assist device improved step length, walking rate, and cadence in the middle-aged women. Bisphosphonate of usual dose did not reduce bone formation and newly developed active vitamin D3 of high dose elevated bone formation in a rat model using 4-point bending device.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (18 results)

All 2015 2014 2013

All Journal Article (9 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 3 results,  Open Access: 1 results) Presentation (9 results) (of which Int'l Joint Research: 2 results,  Invited: 4 results)

  • [Journal Article] Epidemiology of fragility fractures in Sakaiminato, Japan: incidence, secular trends, and prognosis2015

    • Author(s)
      Tsukutani Y, Hagino H, Ito Y, Nagashima H
    • Journal Title

      Osteoporos Int

      Volume: 26 Issue: 9 Pages: 2249-2255

    • DOI

      10.1007/s00198-015-3124-z

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effects of eldecalcitol on cortical bone response to mechanical loading in rats2015

    • Author(s)
      Yamasaki Y, Nagira K, Osaki M, Nagashima H, Hagino H
    • Journal Title

      BMC Musculoskelet Disord

      Volume: 16 Issue: 1

    • DOI

      10.1186/s12891-015-0613-3

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 大腿骨近位部骨折を予防するための薬物治療2015

    • Author(s)
      萩野 浩
    • Journal Title

      THE BONE

      Volume: 29 Pages: 39-43

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 日本における骨粗鬆症検診が骨折発生率および公衆衛生に与える影響2015

    • Author(s)
      萩野 浩,Crawford B
    • Journal Title

      日本骨粗鬆症学会雑誌

      Volume: 1 Pages: 37-48

    • NAID

      40020884880

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 橈骨遠位端骨折の疫学と予防2014

    • Author(s)
      萩野 浩
    • Journal Title

      整形・災害外科

      Volume: 57 Pages: 121-128

    • Related Report
      2013 Research-status Report
  • [Journal Article] わが国における高齢者の大腿骨近位部骨折の現状と医療者の役割2013

    • Author(s)
      萩野 浩
    • Journal Title

      医薬ジャーナル

      Volume: 49 Pages: 867-871

    • Related Report
      2013 Research-status Report
  • [Journal Article] ELDECALCITOL; Newly developed active vitamin D3 analog for the treatment of osteoporosis2013

    • Author(s)
      Hagino H
    • Journal Title

      Expert Opinion On Pharmacotherapy

      Volume: 14 Issue: 6 Pages: 817-825

    • DOI

      10.1517/14656566.2013.778825

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 骨折の二次予防を目指した治療戦略2013

    • Author(s)
      萩野 浩,奥田玲子,山本陽子
    • Journal Title

      内科

      Volume: 111 Pages: 619-625

    • Related Report
      2013 Research-status Report
  • [Journal Article] 大腿骨近位部骨折2013

    • Author(s)
      萩野 浩
    • Journal Title

      運動器リハビリテーション

      Volume: 24 Pages: 12-17

    • Related Report
      2013 Research-status Report
  • [Presentation] 非定型大腿骨骨折の疫学2015

    • Author(s)
      萩野 浩
    • Organizer
      第43回日本関節病学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] Recent Cohort of Fragile Fracture in Japan2015

    • Author(s)
      Hagino H
    • Organizer
      4th Scientific Meeting of the Asian Federation of Osteoporosis Societies
    • Place of Presentation
      マカオ(中華人民共和国)
    • Year and Date
      2015-10-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Increase in the Incidence of Femoral Neck Fractures in Tottori, Japan2015

    • Author(s)
      Hagino H, Tsukutani Y, Osaki M, Nagashima H
    • Organizer
      4th FFN Global Congress 2015
    • Place of Presentation
      ロッテルダム(オランダ)
    • Year and Date
      2015-09-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 大腿骨近位部骨折発生率の経年推移2015

    • Author(s)
      萩野 浩、築谷康人、尾崎まり、永島英樹
    • Organizer
      第88回日本整形外科学会総会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] 骨折連鎖と大腿骨近位部骨折を抑制するための予防戦略2015

    • Author(s)
      萩野 浩
    • Organizer
      第88回日本整形外科学会総会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] Japanese experiences in the use of bisphosphonates2013

    • Author(s)
      Hagino H
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research
    • Place of Presentation
      神戸(神戸国際会議場)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] The Epidemiological Challenge of Fragility Fractures in SE Asia Region2013

    • Author(s)
      Hagino H
    • Organizer
      Fragility Fracture Network Meeting Korea 2013
    • Place of Presentation
      韓国ソウル(コエックスインターコンチネンタルホテル)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Fragility Fracture Prevention - Japanese Experience and Perspectives2013

    • Author(s)
      Hagino H
    • Organizer
      4th Asia-Pacific Osteoporosis Meeting
    • Place of Presentation
      香港(香港コンベンションセンター)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 骨粗鬆症における薬剤長期治療の現状と課題2013

    • Author(s)
      萩野 浩
    • Organizer
      第15回日本骨粗鬆症学会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi