| Project/Area Number |
25462506
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KITTA TAKEYA 北海道大学, 北海道大学病院, 講師 (40374441)
NONOMURA KATSUYA 北海道大学, 名誉教授 (60113750)
三井 貴彦 山梨大学, 総合研究部, 講師 (90421966)
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| Co-Investigator(Renkei-kenkyūsha) |
MITSUI TAKAHIKO 山梨大学, 総合研究部, 講師 (90421966)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 尿道下裂 / 内分泌 / 妊孕性 / 停留精巣 / 長期予後 |
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| Outline of Final Research Achievements |
Objectives: Actual post-pubertal penile size and factors affecting it in hypospadias patients were evaluated.Patients and methods: Hypospadias patients whose penile length was evaluated at 15 years old or older were enrolled in the present study.
Results: Multivariate analysis showed that the severity of hypospadias and endocrinological abnormality were significant factors affectingpost-pubertal penile length. Penile length in 25 patients without endocrinological abnormality was significantly longer than that in those with endocrinological abnormality. Among patients without endocrinological abnormality, penile length in 13 with severe hypospadias was significantly shorter than that in 12 with mild hypospadias.Conclusions: While the severity of hypospadias and endocrinological abnormality at post-pubertal evaluation were factors affecting post-pubertal penile size, penile length in patients with severe hypospadias was shorter even in cases without endocrinological abnormality.
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