| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
This research intends to clarify the mechanisms of hearing disorders and to develop better methods of treatments, which are difficult to identify through clinical researches and specimens. Numerical cochlear models in which the active motilities of the outer hair cells and ionic flux are considered have been constructed. Simulations were performed using the models, and the vibrations of the lymph liquid and basilar membrane in the cochlea were analyzed. Through the simulations, the transmission mechanisms in the peripheral auditory systems have been clarified. As clinical applications, the mechanisms of hearing losses caused by otosclerosis and endolymphatic hydrops were investigated. In addition, optimal design of cochlear implant was studied, and the effects of the length and insert position of the electrode of the cochlear implant on residual hearing were investigated.
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