Clinical application of transcorneal retinal electrical stimulation
Project/Area Number |
25462735
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Ophthalmology
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Research Institution | Saitama Medical University (2016) Teikyo University (2013-2015) |
Principal Investigator |
Shinoda Kei 埼玉医科大学, 医学部, 教授 (60245561)
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Co-Investigator(Kenkyū-buntansha) |
今村 裕 帝京大学, 医学部, 准教授 (20276215)
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Project Period (FY) |
2013-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 電気刺激 / 網膜治療 / 角膜コンタクトレンズ電極 / 皮膚電極 / 網膜電図 / 視覚誘発電位 / パターン刺激 / 液晶モニター / 有機ELモニター / 網膜電気刺激 / 経角膜電気刺激 / EER / Phosphene / パターンERG / パターンVEP / CRTモニター / 視覚刺激装置 / 経角膜網膜電気刺激 |
Outline of Final Research Achievements |
The CRT monitor has been used as a visual stimulation device for multifocal electroretinogram (mfERG) and visual evoked potentials (VEP) recordings. mf ERG and VEP are usuful clinical testings for evaluating safety and effectiveness of the transcorneal retinal electrical stimulation (TES). However,the CRT monitor is not available any more. Therefore we looked for other monitor instead. We evaluated liquid crystal display and organic EL display as a stimulation device for mfERG and VEP and found that each device can be used for such testings when some different aspects of each monitor can be understood and considered. We investigated some kinds of electrodes and their positions for TES by recording electrically evoked response (EER) and found that skin electrode is effective as corneal contact electrode (Brian-Allen electrode). The effective position is thought to be on the upper and lower lid. And for the recordings, bipolar recording is reccomended.
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Report
(5 results)
Research Products
(68 results)
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[Journal Article] Novel RP1L1 Variants and Genotype-Photoreceptor Microstructural Phenotype Associations in Cohort of Japanese Patients With Occult Macular Dystrophy.2016
Author(s)
Fujinami K, Kameya S, Kikuchi S, Ueno S, Kondo M, Hayashi T, Shinoda K, Machida S, Kuniyoshi K, Kawamura Y, Akahori M, Yoshitake K, Katagiri S, Nakanishi A, Sakuramoto H, Ozawa Y, Tsubota K, Yamaki K, Mizota A, Terasaki H, Miyake Y, Iwata T, Tsunoda K.
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Journal Title
Invest Ophthalmol Vis Sci.
Volume: 57
Pages: 4837-46
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Electroretinographic evaluations of retinal function before, just after, and after intravitreal injections.2016
Author(s)
Yagura K, Shinoda K, Matsumoto S, Terauchi G, Kawashima M, Watanabe E, Matsumoto H, Iwata T, Mizota A, Miyake Y.
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Journal Title
Sci Rep.
Volume: 6
Pages: 31104-31104
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Clinical and Genetic Findings of Autosomal Recessive Bestrophinopathy in Japanese Cohort.2016
Author(s)
Nakanishi A, Ueno S, Hayashi T, Katagiri S, Kominami T, Ito Y, Gekka T, Masuda Y, Tsuneoka H, Shinoda K, Hirakata A, Inoue M, Fujinami K, Tsunoda K, Iwata T, Terasaki H.
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Journal Title
Am J Ophthalmol.
Volume: 168
Pages: 86-94
NAID
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Detailed analysis of family with autosomal recessive bestrophinopathy associated with new BEST1 mutation.2016
Author(s)
Kubota D, Gocho K, Akeo K, Kikuchi S, Sugahara M, Matsumoto CS, Shinoda K, Mizota A, Yamaki K, Takahashi H, Kameya S.
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Journal Title
Doc Ophthalmol.
Volume: 132
Pages: 233-43
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Presentation] Japan whole exome project for inherited retinal diseases 2014.2015
Author(s)
Fujinami K, Hayashi T, Kuniyoshi K, Kondo M, Ueno S, Shinoda K, Tsubota K, Miyake Y, Tsunoda K, Iwata T.
Organizer
International Society for Clinical Electrophysiology of Vision
Place of Presentation
Ljubljana, Slovenia
Year and Date
2015-06-24
Related Report
Int'l Joint Research
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[Presentation] Vitrectomy and Electroretinogram2014
Author(s)
Kei Shinoda, Soiti Matsumoto, Atsushi Mizota, Yozo Miyake
Organizer
The 112th KOS Clinical Electrophysiology of Vision Symposium
Place of Presentation
Seoul
Year and Date
2014-11-01 – 2014-11-03
Related Report
Invited
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[Presentation] Flicker ERG recording in premature baby2014
Author(s)
Hiroyuki Sakai, Haruka Minoda, Masao Yoshikawa, Emiko Watanabe, Takamasa Tsuboi, Celso Soiti Matsumoto, Kei Shinoda, Atsushi Mizota
Organizer
52nd International Society for Clinical Electrophysiology of Vision
Place of Presentation
Boston
Year and Date
2014-07-20 – 2014-07-24
Related Report
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[Presentation] Pattern visually evoked potentials elicited by2014
Author(s)
Celso Soiti Matsumoto, Kei Shinoda, Harue Matsumoto, Hideaki Funada, Kakeru Sasaki, Haruka Minoda, Takeshi Iwata, Atsushi Mizota
Organizer
52nd International Society for Clinical Electrophysiology of Vision
Place of Presentation
Boston
Year and Date
2014-07-20 – 2014-07-24
Related Report
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