| Project/Area Number |
25462807
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Hyogo Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMOTO So 兵庫医科大学, 医学部, 教授 (30281124)
KAWAI Kenichiro 兵庫医科大学, 医学部, 准教授 (80423177)
SOTSUKA Yohei 兵庫医科大学, 医学部, 助教 (40437413)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 顔面神経 / 神経移植 / 端側神経縫合 / facial nerve / nerve graft / end-to-side neurorrhphy / 顔面神経麻痺 / facial palsy / end-to-side neurorrhaphy / 神経再建 |
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| Outline of Final Research Achievements |
In 10 rabbits, four branches of facial nerve were experimentally sectioned and reconstructed with cable grafts and end-to-side nerve graft with epineural suture and partial neurectomy. Morphological investigation showed that regenerating axons of the facial nerve trunk regenerate into each distal branches.
The technique was applied in 3 patients and satisfactory functional recovery was obtained.
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